chr1 : 18,896,434 – 18,896,684
250 bp 57 TFs 1 linked gene
This 250 bp open chromatin element is linked to ALDH4A1 and is bound by 57 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ALDH4A1 5.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:18,891,434 – 18,901,684
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
57 transcription factors
Source
Cell type
ADNP 1 dataset
ChIP K562 ENCFF492SKF 250 bp overlap
ARID1B 1 dataset
ChIP K562 ENCFF938UXQ 250 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 143 bp overlap
ChIP K562 ENCFF673OEZ 250 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF031ISE 111 bp overlap
ChIP BLaER1 ENCFF460KDD 138 bp overlap
DNMT3B 1 dataset
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 69 bp overlap
E2F6 1 dataset
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
EOMES 2 datasets
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 161 bp overlap
ESRRA 1 dataset
ChIP K-562 ENCSR486IFJ.ESRRA.K-562 161 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 193 bp overlap
EZH2 1 dataset
ChIP hepatocyte ENCFF118DKH 127 bp overlap
EZH2_phosphoT487 1 dataset
ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 250 bp overlap
FIGLA 1 dataset
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 250 bp overlap
ChIP DE DE-FOXA2-2 250 bp overlap
GATA1 5 datasets
ChIP K-562 ENCSR000EFT.GATA1.K-562 167 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 162 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 152 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 174 bp overlap
ChIP K562 ENCFF094CMK 216 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 250 bp overlap
ChIP DE DE-GATA4-2 250 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 191 bp overlap
ChIP foregut GSE117136.GATA4.foregut 250 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 250 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 119 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 203 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 193 bp overlap
ChIP DE DE-GATA6-1 250 bp overlap
ChIP DE DE-GATA6-2 250 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 179 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 250 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 250 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 250 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 250 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 196 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 234 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 155 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 250 bp overlap
ChIP foregut GSE117136.GATA6.foregut 250 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 250 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 250 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 245 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 111 bp overlap
HDAC2 1 dataset
ChIP K-562 ENCSR893WSB.HDAC2.K-562 177 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 174 bp overlap
KLF3 1 dataset
Motif DE_72h DE_72h-KLF3_MA1516.2 10 bp overlap
MGA 1 dataset
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
NEUROD1 1 dataset
ChIP K-562 ENCSR986CDX.NEUROD1.K-562 73 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_72h DE_72h-Nr1h3Rxra_MA0494.2 16 bp overlap
PKNOX2 1 dataset
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
POLR2G 1 dataset
ChIP HepG2 ENCFF241AEG 232 bp overlap
PRDM1 1 dataset
Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap
Ptf1A 1 dataset
Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap
RORA 1 dataset
Motif DE_72h DE_72h-RORA_MA0072.2 11 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 250 bp overlap
SNAI2 1 dataset
Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap
SNAI3 1 dataset
Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 239 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 250 bp overlap
TAL1 3 datasets
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 142 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 191 bp overlap
ChIP K562 ENCFF661CCK 249 bp overlap
TBR1 1 dataset
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX21 1 dataset
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 1 dataset
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TFAP2A 1 dataset
Motif DE_72h DE_72h-TFAP2A_MA0810.2 11 bp overlap
TGIF1 1 dataset
Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap
TGIF2 1 dataset
Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap
Tbx6 1 dataset
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
ZBTB18 1 dataset
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZBTB24 1 dataset
Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap
ZEB1 1 dataset
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF213 1 dataset
Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap
ZNF331 1 dataset
Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap
ZNF454 1 dataset
Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap
ZNF675 1 dataset
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF692 1 dataset
Motif DE_72h DE_72h-ZNF692_MA1986.2 8 bp overlap
ZNF708 1 dataset
Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap
ZNF768 1 dataset
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
Zfx 2 datasets
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
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