chr7 : 112,427,876 – 112,428,687

811 bp 61 TFs 1 linked gene

This 811 bp open chromatin element is linked to IFRD1 and is bound by 61 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
IFRD1		4.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

ATF7 1 dataset

ChIP MCF-7 ENCFF578WKB 78 bp overlap

Arid3a 1 dataset

Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap

CBX8 1 dataset

ChIP K-562 ENCSR000ATW.CBX8.K-562 228 bp overlap

CRX 3 datasets

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 134 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 232 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 517 bp overlap

CTCF 2 datasets

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 409 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 114 bp overlap

DPRX 1 dataset

Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 239 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 407 bp overlap

ChIP DE DE-FOXA2-2 467 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_36h DE_36h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA1::TAL1 1 dataset

Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 255 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 601 bp overlap

ChIP DE DE-GATA4-2 611 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 651 bp overlap

ChIP DE DE-GATA6-2 455 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 459 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 600 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 419 bp overlap

HOXB4 1 dataset

Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap

ISL1 1 dataset

ChIP SK-N-SH ENCFF285GEQ 101 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 384 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 432 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 431 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 453 bp overlap

JUND 2 datasets

Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap

Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap

MED1 1 dataset

ChIP RH4 GSE83726.MED1.RH4 414 bp overlap

MEF2D 1 dataset

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 222 bp overlap

MEIS1 4 datasets

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

MGA 1 dataset

Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap

MXI1 1 dataset

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

NEUROD1 2 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 192 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 234 bp overlap

NKX6-1 1 dataset

Motif DE_36h DE_36h-NKX6-1_MA0674.2 7 bp overlap

Nr2e3 1 dataset

Motif DE_36h DE_36h-Nr2e3_MA0164.2 6 bp overlap

OTX2 1 dataset

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 301 bp overlap

PAX5 1 dataset

ChIP fetal_testis GSE100639.PAX5.fetal_testis 195 bp overlap

PKNOX2 1 dataset

Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap

POU4F2 1 dataset

Motif DE_36h DE_36h-POU4F2_MA0683.2 15 bp overlap

RORB 1 dataset

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 141 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 334 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 264 bp overlap

SOX10 2 datasets

Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 354 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 402 bp overlap

SOX4 2 datasets

Motif DE_36h DE_36h-SOX4_MA0867.3 8 bp overlap

Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 186 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 189 bp overlap

TBX1 1 dataset

Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap

TBX18 2 datasets

Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap

TBX5 6 datasets

ChIP G296S GSE85628.TBX5.G296S 433 bp overlap

ChIP G296S_2 GSE85628.TBX5.G296S_2 433 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 355 bp overlap

ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 402 bp overlap

ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 397 bp overlap

ChIP hiPSC GSE81585.TBX5.hiPSC 285 bp overlap

TBXT 2 datasets

Motif DE_36h DE_36h-TBXT_MA0009.2 16 bp overlap

Motif DE_48h DE_48h-TBXT_MA0009.2 16 bp overlap

TGIF2 1 dataset

Motif DE_36h DE_36h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_36h DE_36h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_36h DE_36h-TGIF2LY_MA1572.1 12 bp overlap

Tbx6 1 dataset

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

USF1 1 dataset

Motif DE_36h DE_36h-USF1_MA0093.4 10 bp overlap

YY2 1 dataset

ChIP HEK293 ENCSR692HSE.YY2.HEK293 248 bp overlap

ZNF28 1 dataset

ChIP HEK293T GSE78099.ZNF28.HEK293T 133 bp overlap

ZNF460 1 dataset

Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap

ZNF558 1 dataset

Motif DE_36h DE_36h-ZNF558_MA2335.1 29 bp overlap

ZNF707 1 dataset

Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap

Zbtb2 1 dataset

Motif DE_36h DE_36h-Zbtb2_MA2340.1 10 bp overlap

Zfx 1 dataset

Motif DE_36h DE_36h-Zfx_MA0146.3 10 bp overlap