chr4 : 177,593,780 – 177,594,263

483 bp 76 TFs 1 linked gene

This 483 bp open chromatin element is linked to AGA-DT and is bound by 76 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
AGA-DT		2.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

76 transcription factors

ALX3 1 dataset

Motif DE_60h DE_60h-ALX3_MA0634.2 6 bp overlap

AR 2 datasets

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 138 bp overlap

ChIP prostate_1816_T GSE130408.AR.prostate_1816_T 256 bp overlap

BARX2 1 dataset

Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap

BCL6B 1 dataset

Motif DE_60h DE_60h-BCL6B_MA0731.1 17 bp overlap

CDX2 1 dataset

Motif DE_60h DE_60h-CDX2_MA0465.3 8 bp overlap

CREB5 1 dataset

ChIP LNCaP GSE137775.CREB5.LNCaP 188 bp overlap

DRGX 1 dataset

Motif DE_60h DE_60h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif DE_60h DE_60h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_60h DE_60h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_60h DE_60h-EN1_MA0027.3 6 bp overlap

EVX1 1 dataset

Motif DE_60h DE_60h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_60h DE_60h-EVX2_MA0888.2 6 bp overlap

FOXA1 7 datasets

ChIP HEK293_i176m_TFS GSE123618.FOXA1.HEK293_i176m_TFS 95 bp overlap

ChIP HEK293_r261g_TFS GSE123618.FOXA1.HEK293_r261g_TFS 193 bp overlap

ChIP HEK293_v5_TFS GSE123618.FOXA1.HEK293_v5_TFS 100 bp overlap

ChIP LNCaP GSE64656.FOXA1.LNCaP 253 bp overlap

ChIP LNCaP_M253K GSE133386.FOXA1.LNCaP_M253K 105 bp overlap

ChIP LNCaP_SHFOXA1_R1881 GSE37345.FOXA1.LNCaP_SHFOXA1_R1881 132 bp overlap

ChIP prostate_P7_T GSE130408.FOXA1.prostate_P7_T 157 bp overlap

FOXA2 8 datasets

ChIP BJ1-hTERT GSE90454.FOXA2.BJ1-hTERT 110 bp overlap

ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 154 bp overlap

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 130 bp overlap

ChIP BJ1-hTERT_Mimo GSE90454.FOXA2.BJ1-hTERT_Mimo 76 bp overlap

ChIP BJ1-hTERT_MimosineRelease GSE90454.FOXA2.BJ1-hTERT_MimosineRelease 53 bp overlap

ChIP DE DE-FOXA2-1 470 bp overlap

ChIP DE DE-FOXA2-2 392 bp overlap

ChIP KerCT GSE90454.FOXA2.KerCT 89 bp overlap

GATA2 2 datasets

ChIP LNCaP GSE38391.GATA2.LNCaP 56 bp overlap

ChIP LNCaP GSE52725.GATA2.LNCaP 56 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 477 bp overlap

ChIP DE DE-GATA4-2 483 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 428 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 441 bp overlap

ChIP DE DE-GATA6-2 483 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 202 bp overlap

GSX1 1 dataset

Motif DE_60h DE_60h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_60h DE_60h-GSX2_MA0893.3 7 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

HOXA1 1 dataset

Motif DE_60h DE_60h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_60h DE_60h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_60h DE_60h-HOXA3_MA2119.1 7 bp overlap

HOXA6 1 dataset

Motif DE_60h DE_60h-HOXA6_MA1497.2 7 bp overlap

HOXB1 1 dataset

Motif DE_60h DE_60h-HOXB1_MA2093.1 7 bp overlap

HOXB13 6 datasets

ChIP prostate-cancer_PDX_170-2 GSE130408.HOXB13.prostate-cancer_PDX_170-2 64 bp overlap

ChIP prostate_2078_T GSE130408.HOXB13.prostate_2078_T 165 bp overlap

ChIP prostate_2480_T GSE130408.HOXB13.prostate_2480_T 156 bp overlap

ChIP prostate_2483_T GSE130408.HOXB13.prostate_2483_T 183 bp overlap

ChIP prostate_P25 GSE130408.HOXB13.prostate_P25 168 bp overlap

ChIP prostate_P7_T GSE130408.HOXB13.prostate_P7_T 187 bp overlap

HOXB2 1 dataset

Motif DE_60h DE_60h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_60h DE_60h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_60h DE_60h-HOXB5_MA0904.3 6 bp overlap

HOXB6 1 dataset

Motif DE_60h DE_60h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_60h DE_60h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_60h DE_60h-HOXB8_MA1502.2 7 bp overlap

HOXC8 1 dataset

Motif DE_60h DE_60h-HOXC8_MA1505.2 6 bp overlap

HOXD8 1 dataset

Motif DE_60h DE_60h-HOXD8_MA0910.3 7 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap

ISX 1 dataset

Motif DE_60h DE_60h-ISX_MA0654.2 6 bp overlap

LHX5 1 dataset

Motif DE_60h DE_60h-LHX5_MA1519.2 7 bp overlap

Lhx4 1 dataset

Motif DE_60h DE_60h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_60h DE_60h-Lhx8_MA0705.2 6 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 173 bp overlap

MEIS2 1 dataset

Motif DE_60h DE_60h-MEIS2_MA1640.2 9 bp overlap

MEOX1 1 dataset

Motif DE_60h DE_60h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_60h DE_60h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif DE_60h DE_60h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_60h DE_60h-MNX1_MA0707.3 6 bp overlap

NFIB 1 dataset

Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap

NKX6-2 1 dataset

Motif DE_60h DE_60h-NKX6-2_MA0675.2 6 bp overlap

PDX1 1 dataset

Motif DE_60h DE_60h-PDX1_MA0132.3 6 bp overlap

POU1F1 1 dataset

Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap

POU3F1 1 dataset

Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_60h DE_60h-POU3F4_MA0789.1 9 bp overlap

POU5F1B 1 dataset

Motif DE_60h DE_60h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 1 dataset

Motif DE_60h DE_60h-POU6F1_MA0628.2 6 bp overlap

PRRX1 1 dataset

Motif DE_60h DE_60h-PRRX1_MA0716.2 6 bp overlap

RAX2 1 dataset

Motif DE_60h DE_60h-RAX2_MA0717.2 6 bp overlap

SHOX 1 dataset

Motif DE_60h DE_60h-SHOX_MA0630.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 152 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 483 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 179 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 146 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 100 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 295 bp overlap

Shox2 1 dataset

Motif DE_60h DE_60h-Shox2_MA0720.2 6 bp overlap

TBP 1 dataset

Motif DE_60h DE_60h-TBP_MA0108.3 7 bp overlap

TFAP4 1 dataset

ChIP LNCaP GSE28857.TFAP4.LNCaP 173 bp overlap

TLE3 1 dataset

ChIP LNCaP GSE94682.TLE3.LNCaP 166 bp overlap

TLX2 1 dataset

Motif DE_60h DE_60h-TLX2_MA1577.2 6 bp overlap

UNCX 1 dataset

Motif DE_60h DE_60h-UNCX_MA0721.2 6 bp overlap

VAX2 1 dataset

Motif DE_60h DE_60h-VAX2_MA0723.3 6 bp overlap

ZNF354A 1 dataset

Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap

mix-a 1 dataset

Motif DE_60h DE_60h-mix-a_MA0621.2 7 bp overlap