chr4 : 133,253,004 – 133,253,430
426 bp 80 TFs 1 linked gene
This 426 bp open chromatin element is linked to ENSG00000286467 and is bound by 80 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000286467 9.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:133,248,004 – 133,258,430
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
80 transcription factors
Source
Cell type
ALX3 3 datasets
Motif DE_48h DE_48h-ALX3_MA0634.2 6 bp overlap
Motif DE_48h DE_48h-ALX3_MA0634.2 6 bp overlap
Motif DE_48h DE_48h-ALX3_MA0634.2 6 bp overlap
DRGX 3 datasets
Motif DE_48h DE_48h-DRGX_MA1481.2 6 bp overlap
Motif DE_48h DE_48h-DRGX_MA1481.2 6 bp overlap
Motif DE_48h DE_48h-DRGX_MA1481.2 6 bp overlap
EMX1 3 datasets
Motif DE_48h DE_48h-EMX1_MA0612.3 6 bp overlap
Motif DE_48h DE_48h-EMX1_MA0612.3 6 bp overlap
Motif DE_48h DE_48h-EMX1_MA0612.3 6 bp overlap
EMX2 3 datasets
Motif DE_48h DE_48h-EMX2_MA0886.2 6 bp overlap
Motif DE_48h DE_48h-EMX2_MA0886.2 6 bp overlap
Motif DE_48h DE_48h-EMX2_MA0886.2 6 bp overlap
EN1 3 datasets
Motif DE_48h DE_48h-EN1_MA0027.3 6 bp overlap
Motif DE_48h DE_48h-EN1_MA0027.3 6 bp overlap
Motif DE_48h DE_48h-EN1_MA0027.3 6 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 257 bp overlap
EVX1 3 datasets
Motif DE_48h DE_48h-EVX1_MA0887.2 6 bp overlap
Motif DE_48h DE_48h-EVX1_MA0887.2 6 bp overlap
Motif DE_48h DE_48h-EVX1_MA0887.2 6 bp overlap
EVX2 3 datasets
Motif DE_48h DE_48h-EVX2_MA0888.2 6 bp overlap
Motif DE_48h DE_48h-EVX2_MA0888.2 6 bp overlap
Motif DE_48h DE_48h-EVX2_MA0888.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 426 bp overlap
ChIP DE DE-FOXA2-2 415 bp overlap
FOXB1 2 datasets
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Foxn1 1 dataset
Motif DE_48h DE_48h-Foxn1_MA1684.1 6 bp overlap
GATA3 1 dataset
ChIP Kelly GSE94822.GATA3.Kelly 166 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 426 bp overlap
ChIP DE DE-GATA4-2 418 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 377 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 277 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 385 bp overlap
ChIP DE DE-GATA6-2 426 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 377 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 426 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 426 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 426 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 426 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 426 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 350 bp overlap
GSX1 3 datasets
Motif DE_48h DE_48h-GSX1_MA0892.2 6 bp overlap
Motif DE_48h DE_48h-GSX1_MA0892.2 6 bp overlap
Motif DE_48h DE_48h-GSX1_MA0892.2 6 bp overlap
GSX2 3 datasets
Motif DE_48h DE_48h-GSX2_MA0893.3 7 bp overlap
Motif DE_48h DE_48h-GSX2_MA0893.3 7 bp overlap
Motif DE_48h DE_48h-GSX2_MA0893.3 7 bp overlap
HOXA1 3 datasets
Motif DE_48h DE_48h-HOXA1_MA1495.2 6 bp overlap
Motif DE_48h DE_48h-HOXA1_MA1495.2 6 bp overlap
Motif DE_48h DE_48h-HOXA1_MA1495.2 6 bp overlap
HOXA2 3 datasets
Motif DE_48h DE_48h-HOXA2_MA0900.3 6 bp overlap
Motif DE_48h DE_48h-HOXA2_MA0900.3 6 bp overlap
Motif DE_48h DE_48h-HOXA2_MA0900.3 6 bp overlap
HOXA3 3 datasets
Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap
Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap
Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap
HOXA6 3 datasets
Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap
Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap
Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap
HOXB1 3 datasets
Motif DE_48h DE_48h-HOXB1_MA2093.1 7 bp overlap
Motif DE_48h DE_48h-HOXB1_MA2093.1 7 bp overlap
Motif DE_48h DE_48h-HOXB1_MA2093.1 7 bp overlap
HOXB2 3 datasets
Motif DE_48h DE_48h-HOXB2_MA0902.3 6 bp overlap
Motif DE_48h DE_48h-HOXB2_MA0902.3 6 bp overlap
Motif DE_48h DE_48h-HOXB2_MA0902.3 6 bp overlap
HOXB3 3 datasets
Motif DE_48h DE_48h-HOXB3_MA0903.2 6 bp overlap
Motif DE_48h DE_48h-HOXB3_MA0903.2 6 bp overlap
Motif DE_48h DE_48h-HOXB3_MA0903.2 6 bp overlap
HOXB5 3 datasets
Motif DE_48h DE_48h-HOXB5_MA0904.3 6 bp overlap
Motif DE_48h DE_48h-HOXB5_MA0904.3 6 bp overlap
Motif DE_48h DE_48h-HOXB5_MA0904.3 6 bp overlap
HOXB6 3 datasets
Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap
Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap
Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap
HOXB7 3 datasets
Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap
Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap
Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap
HOXB8 3 datasets
Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap
Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap
Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap
HOXC8 3 datasets
Motif DE_48h DE_48h-HOXC8_MA1505.2 6 bp overlap
Motif DE_48h DE_48h-HOXC8_MA1505.2 6 bp overlap
Motif DE_48h DE_48h-HOXC8_MA1505.2 6 bp overlap
HOXD8 3 datasets
Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap
Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap
Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap
Hmx2 1 dataset
Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 222 bp overlap
ISX 3 datasets
Motif DE_48h DE_48h-ISX_MA0654.2 6 bp overlap
Motif DE_48h DE_48h-ISX_MA0654.2 6 bp overlap
Motif DE_48h DE_48h-ISX_MA0654.2 6 bp overlap
LHX5 3 datasets
Motif DE_48h DE_48h-LHX5_MA1519.2 7 bp overlap
Motif DE_48h DE_48h-LHX5_MA1519.2 7 bp overlap
Motif DE_48h DE_48h-LHX5_MA1519.2 7 bp overlap
Lef1 1 dataset
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Lhx3 2 datasets
Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap
Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap
Lhx4 3 datasets
Motif DE_48h DE_48h-Lhx4_MA0704.2 6 bp overlap
Motif DE_48h DE_48h-Lhx4_MA0704.2 6 bp overlap
Motif DE_48h DE_48h-Lhx4_MA0704.2 6 bp overlap
Lhx8 3 datasets
Motif DE_48h DE_48h-Lhx8_MA0705.2 6 bp overlap
Motif DE_48h DE_48h-Lhx8_MA0705.2 6 bp overlap
Motif DE_48h DE_48h-Lhx8_MA0705.2 6 bp overlap
MEOX1 3 datasets
Motif DE_48h DE_48h-MEOX1_MA0661.2 7 bp overlap
Motif DE_48h DE_48h-MEOX1_MA0661.2 7 bp overlap
Motif DE_48h DE_48h-MEOX1_MA0661.2 7 bp overlap
MEOX2 3 datasets
Motif DE_48h DE_48h-MEOX2_MA0706.2 7 bp overlap
Motif DE_48h DE_48h-MEOX2_MA0706.2 7 bp overlap
Motif DE_48h DE_48h-MEOX2_MA0706.2 7 bp overlap
MIXL1 3 datasets
Motif DE_48h DE_48h-MIXL1_MA0662.2 6 bp overlap
Motif DE_48h DE_48h-MIXL1_MA0662.2 6 bp overlap
Motif DE_48h DE_48h-MIXL1_MA0662.2 6 bp overlap
MNX1 3 datasets
Motif DE_48h DE_48h-MNX1_MA0707.3 6 bp overlap
Motif DE_48h DE_48h-MNX1_MA0707.3 6 bp overlap
Motif DE_48h DE_48h-MNX1_MA0707.3 6 bp overlap
NKX2-2 3 datasets
Motif DE_36h DE_36h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
NKX2-5 3 datasets
Motif DE_36h DE_36h-NKX2-5_MA0063.3 7 bp overlap
Motif DE_48h DE_48h-NKX2-5_MA0063.3 7 bp overlap
Motif DE_60h DE_60h-NKX2-5_MA0063.3 7 bp overlap
NKX6-2 3 datasets
Motif DE_48h DE_48h-NKX6-2_MA0675.2 6 bp overlap
Motif DE_48h DE_48h-NKX6-2_MA0675.2 6 bp overlap
Motif DE_48h DE_48h-NKX6-2_MA0675.2 6 bp overlap
NR1D1 2 datasets
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
Motif DE_60h DE_60h-NR1D1_MA1531.2 14 bp overlap
NR1D2 2 datasets
Motif DE_48h DE_48h-NR1D2_MA1532.2 15 bp overlap
Motif DE_60h DE_60h-NR1D2_MA1532.2 15 bp overlap
Nr2F6 2 datasets
Motif DE_48h DE_48h-Nr2F6_MA0728.1 15 bp overlap
Motif DE_60h DE_60h-Nr2F6_MA0728.1 15 bp overlap
OSR1 1 dataset
Motif DE_48h DE_48h-OSR1_MA1542.2 8 bp overlap
PDX1 3 datasets
Motif DE_48h DE_48h-PDX1_MA0132.3 6 bp overlap
Motif DE_48h DE_48h-PDX1_MA0132.3 6 bp overlap
Motif DE_48h DE_48h-PDX1_MA0132.3 6 bp overlap
PHOX2A 2 datasets
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
POU6F1 3 datasets
Motif DE_48h DE_48h-POU6F1_MA0628.2 6 bp overlap
Motif DE_48h DE_48h-POU6F1_MA0628.2 6 bp overlap
Motif DE_48h DE_48h-POU6F1_MA0628.2 6 bp overlap
PRDM1 1 dataset
ChIP fetal_testis GSE100639.PRDM1.fetal_testis 95 bp overlap
PRRX1 3 datasets
Motif DE_48h DE_48h-PRRX1_MA0716.2 6 bp overlap
Motif DE_48h DE_48h-PRRX1_MA0716.2 6 bp overlap
Motif DE_48h DE_48h-PRRX1_MA0716.2 6 bp overlap
Prdm4 1 dataset
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
RARA 4 datasets
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
Motif DE_60h DE_60h-RARA_MA0729.1 18 bp overlap
ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 230 bp overlap
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 239 bp overlap
RAX2 3 datasets
Motif DE_48h DE_48h-RAX2_MA0717.2 6 bp overlap
Motif DE_48h DE_48h-RAX2_MA0717.2 6 bp overlap
Motif DE_48h DE_48h-RAX2_MA0717.2 6 bp overlap
RFX2 1 dataset
Motif DE_48h DE_48h-RFX2_MA0600.3 14 bp overlap
RFX5 1 dataset
Motif DE_48h DE_48h-RFX5_MA0510.3 14 bp overlap
RXRA::VDR 2 datasets
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
Rarb 2 datasets
Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap
Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap
SATB1 4 datasets
Motif DE_48h DE_48h-SATB1_MA1963.2 7 bp overlap
Motif DE_60h DE_60h-SATB1_MA1963.2 7 bp overlap
ChIP MCF-10A_CP GSE123292.SATB1.MCF-10A_CP 187 bp overlap
ChIP MCF-10A_N-term_CUT1 GSE123292.SATB1.MCF-10A_N-term_CUT1 194 bp overlap
SHOX 3 datasets
Motif DE_48h DE_48h-SHOX_MA0630.2 6 bp overlap
Motif DE_48h DE_48h-SHOX_MA0630.2 6 bp overlap
Motif DE_48h DE_48h-SHOX_MA0630.2 6 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 359 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 253 bp overlap
SMAD2_3 2 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 236 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 345 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 284 bp overlap
Shox2 3 datasets
Motif DE_48h DE_48h-Shox2_MA0720.2 6 bp overlap
Motif DE_48h DE_48h-Shox2_MA0720.2 6 bp overlap
Motif DE_48h DE_48h-Shox2_MA0720.2 6 bp overlap
TCF7 1 dataset
Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap
TCF7L1 1 dataset
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
TLX2 3 datasets
Motif DE_48h DE_48h-TLX2_MA1577.2 6 bp overlap
Motif DE_48h DE_48h-TLX2_MA1577.2 6 bp overlap
Motif DE_48h DE_48h-TLX2_MA1577.2 6 bp overlap
UNCX 3 datasets
Motif DE_48h DE_48h-UNCX_MA0721.2 6 bp overlap
Motif DE_48h DE_48h-UNCX_MA0721.2 6 bp overlap
Motif DE_48h DE_48h-UNCX_MA0721.2 6 bp overlap
VAX2 3 datasets
Motif DE_48h DE_48h-VAX2_MA0723.3 6 bp overlap
Motif DE_48h DE_48h-VAX2_MA0723.3 6 bp overlap
Motif DE_48h DE_48h-VAX2_MA0723.3 6 bp overlap
ZBTB24 1 dataset
Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap
ZIM3 1 dataset
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
ZNF214 1 dataset
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
ZNF324 1 dataset
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
ZNF528 1 dataset
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
ZNF652 2 datasets
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
mix-a 3 datasets
Motif DE_48h DE_48h-mix-a_MA0621.2 7 bp overlap
Motif DE_48h DE_48h-mix-a_MA0621.2 7 bp overlap
Motif DE_48h DE_48h-mix-a_MA0621.2 7 bp overlap
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