chr4 : 38,286,978 – 38,287,846

868 bp 64 TFs 1 linked gene

This 868 bp open chromatin element is linked to ENSG00000251642 and is bound by 64 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000251642		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

AR 1 dataset

ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 163 bp overlap

ASCL1 2 datasets

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BRD4 2 datasets

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 154 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-pos 273 bp overlap

BRF1 1 dataset

ChIP H9 GSE94418.BRF1.H9 136 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 377 bp overlap

CTCFL 1 dataset

Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 220 bp overlap

ELF1 1 dataset

ChIP A-549 GSE122203.ELF1.A-549 122 bp overlap

EP300 2 datasets

ChIP neural ENCSR843ZUP.EP300.neural 270 bp overlap

ChIP neural cell ENCFF442QNK 517 bp overlap

ERF::NHLH1 1 dataset

Motif DE_12h DE_12h-ERFNHLH1_MA1938.2 16 bp overlap

ESR1 1 dataset

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 100 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

GATA6 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 557 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 275 bp overlap

GTF2B 1 dataset

ChIP IMR-90_TERT GSE38303.GTF2B.IMR-90_TERT 114 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 153 bp overlap

JUN 1 dataset

ChIP 786-O GSE86092.JUN.786-O 104 bp overlap

MED26 1 dataset

ChIP U2OS_SHCTR GSE73742.MED26.U2OS_SHCTR 108 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYOD1 1 dataset

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 410 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 320 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 701 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 353 bp overlap

ChIP hESC GSE18292.NANOG.hESC 139 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

NR3C1 1 dataset

ChIP HeLa-B2_GRKD_TA_TNFA GSE24518.NR3C1.HeLa-B2_GRKD_TA_TNFA 98 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 167 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU5F1 5 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 394 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 271 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 408 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 148 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 77 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RARA 1 dataset

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 411 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 329 bp overlap

ChIP neural cell ENCFF882LXX 505 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 139 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 152 bp overlap

SMARCA4 3 datasets

ChIP NSC GSE125033.SMARCA4.NSC 783 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 677 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 273 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 283 bp overlap

SMARCC1 3 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 280 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 321 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 266 bp overlap

SNAI1 1 dataset

Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap

SNAI2 1 dataset

Motif DE_12h DE_12h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap

SOX13 1 dataset

Motif DE_12h DE_12h-SOX13_MA1120.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 271 bp overlap

SOX2 5 datasets

Motif DE_12h DE_12h-SOX2_MA0143.5 7 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 498 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 183 bp overlap

ChIP RENVM_SHSOX2 GSE49404.SOX2.RENVM_SHSOX2 131 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 315 bp overlap

Sox1 1 dataset

Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap

Sox17 1 dataset

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Sox3 1 dataset

Motif DE_12h DE_12h-Sox3_MA0514.3 7 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

TCF12 1 dataset

Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap

TCF3 1 dataset

Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap

TCF4 1 dataset

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

USF1 7 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 113 bp overlap

ChIP HepG2 ENCFF807KYJ 201 bp overlap

ChIP K-562 ENCSR000BKT.USF1.K-562 133 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 111 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 191 bp overlap

ChIP WTC11 ENCFF699QGS 397 bp overlap

USF2 1 dataset

ChIP WTC11 ENCFF139JAW 417 bp overlap

YY2 1 dataset

Motif DE_12h DE_12h-YY2_MA0748.3 7 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 298 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 215 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 77 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

ZNF76 1 dataset

Motif DE_12h DE_12h-ZNF76_MA1716.2 17 bp overlap

Zfp335 1 dataset

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap