chr1 : 45,216,712 – 45,217,234
522 bp 42 TFs 8 linked genes
This 522 bp open chromatin element is linked to 8 target genes and is bound by 42 transcription factors.
Linked Genes
8 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ZSWIM5 10.4 kb Distal Multiome
TOE1 123.2 kb Distal Multiome
MUTYH 123.4 kb Distal Multiome
UROD 204.8 kb Distal Multiome+HiCAR
HECTD3 205.7 kb Distal Multiome+HiCAR
EIF2B3 230.4 kb Distal Multiome
TESK2 274.1 kb Distal Multiome
MMACHC 283.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:45,211,712 – 45,222,234
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
42 transcription factors
Source
Cell type
ASCL1 1 dataset
Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 251 bp overlap
EGR1 1 dataset
Motif DE_72h DE_72h-EGR1_MA0162.5 10 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 277 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 1 dataset
ChIP DND41 ENCSR000ASW.EZH2.DND41 118 bp overlap
FIGLA 1 dataset
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 522 bp overlap
ChIP DE DE-FOXA2-2 500 bp overlap
GATA2 1 dataset
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 122 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 522 bp overlap
ChIP DE DE-GATA4-2 522 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 337 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 319 bp overlap
GATA5 1 dataset
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 522 bp overlap
ChIP DE DE-GATA6-2 522 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 409 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 461 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 366 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 494 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 480 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 421 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 396 bp overlap
ChIP foregut GSE117136.GATA6.foregut 365 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 311 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 312 bp overlap
IKZF2 1 dataset
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
MYB 1 dataset
Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap
NFATC3 1 dataset
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NR1H4::RXRA 1 dataset
Motif DE_72h DE_72h-NR1H4RXRA_MA1146.2 13 bp overlap
NR2F1 1 dataset
Motif DE_72h DE_72h-NR2F1_MA1538.1 15 bp overlap
Nfat5 2 datasets
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 1 dataset
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap
POU4F2 1 dataset
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 95 bp overlap
PPARG 1 dataset
Motif DE_72h DE_72h-PPARG_MA0066.2 19 bp overlap
PRDM9 1 dataset
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
RORA 2 datasets
Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap
Motif DE_72h DE_72h-RORA_MA0072.2 11 bp overlap
RORB 1 dataset
Motif DE_72h DE_72h-RORB_MA1150.2 10 bp overlap
RORC 1 dataset
Motif DE_72h DE_72h-RORC_MA1151.2 10 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 354 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 512 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 471 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 397 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 362 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 445 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 365 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 522 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 447 bp overlap
SMAD3 2 datasets
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 162 bp overlap
ChIP endoderm GSE29422.SMAD3.endoderm 377 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 329 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 360 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 365 bp overlap
STAT3 1 dataset
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
Six3 1 dataset
Motif DE_72h DE_72h-Six3_MA0631.2 11 bp overlap
Stat4 1 dataset
Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap
TCF4 1 dataset
Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap
YY1AP1 1 dataset
ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 107 bp overlap
ZBTB18 1 dataset
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZEB1 1 dataset
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF143 2 datasets
ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 157 bp overlap
ChIP HeLa GSE39263.ZNF143.HeLa 258 bp overlap
ZNF8 1 dataset
Motif DE_72h DE_72h-ZNF8_MA1718.1 20 bp overlap
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