chr2 : 165,707,538 – 165,708,219

681 bp 57 TFs 1 linked gene

This 681 bp open chromatin element is linked to ENSG00000293576 and is bound by 57 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000293576		7.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

57 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

CREB1 1 dataset

Motif ES_0h ES_0h-CREB1_MA0018.5 8 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

ELK1::HOXB13 1 dataset

Motif DE_12h DE_12h-ELK1HOXB13_MA1932.2 15 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_12h DE_12h-ETV5HOXA2_MA1948.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

GATA6 5 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 436 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 559 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 264 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 214 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 174 bp overlap

HIC2 2 datasets

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HIF1A 1 dataset

Motif DE_12h DE_12h-HIF1A_MA1106.2 6 bp overlap

HMBOX1 1 dataset

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

JUN 7 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 68 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 279 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 472 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 488 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 483 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 458 bp overlap

Motif ES_0h ES_0h-JUN_MA0488.2 10 bp overlap

MAFF 1 dataset

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MGA::EVX1 1 dataset

Motif ES_0h ES_0h-MGAEVX1_MA1960.2 11 bp overlap

Mafb 1 dataset

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

NANOG 5 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 180 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 367 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 146 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 84 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

NRL 1 dataset

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

Nr1h3::Rxra 1 dataset

Motif DE_12h DE_12h-Nr1h3Rxra_MA0494.2 16 bp overlap

Nr2f6 1 dataset

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU4F2 1 dataset

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 272 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 404 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

Prdm4 2 datasets

Motif DE_12h DE_12h-Prdm4_MA1647.3 11 bp overlap

Motif ES_0h ES_0h-Prdm4_MA1647.3 11 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 272 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

TEAD1 2 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

TEAD2 2 datasets

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

Motif ES_0h ES_0h-TEAD2_MA1121.2 7 bp overlap

TEAD3 2 datasets

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

THAP1 1 dataset

Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap

THRA 1 dataset

Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap

THRB 1 dataset

Motif DE_12h DE_12h-THRB_MA1574.2 13 bp overlap

Wt1 2 datasets

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

ZBTB6 1 dataset

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZIC1 1 dataset

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF341 1 dataset

Motif ES_0h ES_0h-ZNF341_MA1655.2 8 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF449 1 dataset

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF684 1 dataset

Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap

ZNF707 2 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap