chr2:61,157,943–61,158,813

chr2 : 61,157,943 – 61,158,813

870 bp 49 TFs 6 linked genes

This 870 bp open chromatin element is linked to 6 target genes and is bound by 49 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
C2orf74		13.4 kb	Distal	Multiome
C2orf74-DT		13.6 kb	Distal	Multiome
SANBR		92.7 kb	Distal	Multiome
PUS10		140.3 kb	Distal	Multiome
PEX13		140.8 kb	Distal	Multiome
REL		277.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

ChIP THP-1_R1881 GSE131381.AR.THP-1_R1881 171 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD2.K-562_dilution-6-100 129 bp overlap

BRD3 3 datasets

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 89 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 141 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 151 bp overlap

BRD4 2 datasets

ChIP THP-1_DMSO GSE138084.BRD4.THP-1_DMSO 276 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 189 bp overlap

CDK9 2 datasets

ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 177 bp overlap

ChIP MV4-11_DMSO GSE82116.CDK9.MV4-11_DMSO 218 bp overlap

CREBBP 1 dataset

ChIP monocyte_IFNg-LPS GSE131294.CREBBP.monocyte_IFNg-LPS 185 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF093OYK 75 bp overlap

ChIP ProEs GSE59087.EED.ProEs 148 bp overlap

EGR1 3 datasets

ChIP fibroblast_DOX-24h GSE134924.EGR1.fibroblast_DOX-24h 193 bp overlap

ChIP macrophage_D3 GSE136216.EGR1.macrophage_D3 165 bp overlap

ChIP macrophage_D4 GSE136216.EGR1.macrophage_D4 212 bp overlap

ChIP K-562 ENCSR502OEK.ELF1.K-562 239 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 426 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 187 bp overlap

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 102 bp overlap

ChIP induced-endothelial-cell_Veh GSE123906.ETV2.induced-endothelial-cell_Veh 181 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 612 bp overlap

ChIP DE DE-FOXA2-2 611 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 256 bp overlap

FOXP1 1 dataset

ChIP SU-DHL-6 ERP010999.FOXP1.SU-DHL-6 87 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 685 bp overlap

ChIP DE DE-GATA4-2 697 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 750 bp overlap

ChIP DE DE-GATA6-2 662 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 295 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 460 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 367 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 659 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 526 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 273 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 478 bp overlap

IRF4 2 datasets

ChIP OCI-Ly3 GSE142493.IRF4.OCI-Ly3 137 bp overlap

ChIP OCI-Ly3_SHCTR GSE56857.IRF4.OCI-Ly3_SHCTR 199 bp overlap

ChIP THP-1 GSE123872.IRF8.THP-1 180 bp overlap

JMJD1C 1 dataset

ChIP THP-1 GSE63484.JMJD1C.THP-1 148 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 285 bp overlap

KMT2A 1 dataset

ChIP THP-1 GSE79899.KMT2A.THP-1 232 bp overlap

ChIP liver ENCFF584QGB 50 bp overlap

MLLT1_FKB 1 dataset

ChIP MV4-11 GSE82116.MLLT1_FKB.MV4-11 179 bp overlap

NCOA2 1 dataset

ChIP MCF-7 ERP000901.NCOA2.MCF-7 91 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 96 bp overlap

NR4A1 1 dataset

ChIP MOLM-14_DHE GSE124963.NR4A1.MOLM-14_DHE 161 bp overlap

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 166 bp overlap

RUNX1 1 dataset

ChIP THP-1 GSE79899.RUNX1.THP-1 205 bp overlap

ChIP macrophage ERP008801.RXR.macrophage 240 bp overlap

SETDB1 4 datasets

ChIP HEK293 ENCFF676PLV 582 bp overlap

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 430 bp overlap

ChIP K-562 ENCSR000EWI.SETDB1.K-562 201 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 430 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 677 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 585 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 304 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 502 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 666 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 556 bp overlap

ChIP monocyte_IFNg-LPS GSE120943.SMC1.monocyte_IFNg-LPS 239 bp overlap

SMC1A 1 dataset

ChIP monocyte_INFg GSE98367.SMC1A.monocyte_INFg 184 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 208 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 399 bp overlap

SPI1 18 datasets

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 215 bp overlap

ChIP DC GSE123347.SPI1.DC 234 bp overlap

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 252 bp overlap

ChIP DC_LPS GSE123347.SPI1.DC_LPS 171 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 196 bp overlap

ChIP GM12878 ENCFF134LCP 87 bp overlap

ChIP GM12891 ENCFF563IUT 116 bp overlap

ChIP GM12891 ENCSR000BIJ.SPI1.GM12891 157 bp overlap

ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 204 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 150 bp overlap

ChIP THP-1_DIFF GSE25426.SPI1.THP-1_DIFF 140 bp overlap

ChIP macrophage_D7_donorP GSE128834.SPI1.macrophage_D7_donorP 225 bp overlap

ChIP monocyte GSE31621.SPI1.monocyte 155 bp overlap

ChIP monocyte_MACROPHAGE GSE31621.SPI1.monocyte_MACROPHAGE 223 bp overlap

ChIP primary-B-cell_donorA GSE128834.SPI1.primary-B-cell_donorA 135 bp overlap

ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 230 bp overlap

ChIP primary-monocyte_4h_donorO GSE128834.SPI1.primary-monocyte_4h_donorO 184 bp overlap

ChIP primary-monocyte_LPS-4h_donorO GSE128834.SPI1.primary-monocyte_LPS-4h_donorO 203 bp overlap

ChIP OCI-Ly3_SHCTR GSE56857.SPIB.OCI-Ly3_SHCTR 203 bp overlap

STAT1 2 datasets

ChIP CD14_INFG GSE43036.STAT1.CD14_INFG 154 bp overlap

ChIP CD14_INFG_LPS GSE43036.STAT1.CD14_INFG_LPS 179 bp overlap

STAT3 4 datasets

ChIP monocyte_IFNg-LPS GSE120943.STAT3.monocyte_IFNg-LPS 247 bp overlap

ChIP monocyte_IL10 GSE120943.STAT3.monocyte_IL10 189 bp overlap

ChIP monocyte_LPS GSE120943.STAT3.monocyte_LPS 232 bp overlap

ChIP monocyte_resting GSE120943.STAT3.monocyte_resting 150 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 230 bp overlap

TEAD4 1 dataset

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 175 bp overlap

TRIM24 1 dataset

ChIP MOLM-13_IACS-9571 GSE100571.TRIM24.MOLM-13_IACS-9571 324 bp overlap

TRIM28 1 dataset

ChIP K-562 ENCSR474CVP.TRIM28.K-562 296 bp overlap

ZNF143 5 datasets

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 127 bp overlap

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 137 bp overlap

ChIP K-562 GSE39263.ZNF143.K-562 217 bp overlap

ChIP MCF-7 GSE76454.ZNF143.MCF-7 211 bp overlap

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 158 bp overlap

ZNF799 1 dataset

ChIP HEK293T GSE78099.ZNF799.HEK293T 230 bp overlap