Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF799. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF799 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF799, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:12,139,827–12,140,825 | 261.0 kb | Distal (>10kb) Multiome | 594 | |
| chr19:12,156,210–12,156,965 | 244.6 kb | Distal (>10kb) Multiome | 638 | |
| chr19:12,162,692–12,163,608 | 238.2 kb | Distal (>10kb) Multiome | 697 | |
| chr19:12,365,585–12,366,054 | 35.5 kb | Distal (>10kb) Multiome | 577 | |
| chr19:12,400,090–12,401,657 | 80 bp | At TSS Multiome | 671 | |
| chr19:12,440,217–12,441,483 | 39.8 kb | Distal (>10kb) Multiome | 565 | |
| chr19:12,484,131–12,485,387 | 83.5 kb | Distal (>10kb) Multiome | 664 | |
| chr19:12,495,009–12,495,882 | 94.2 kb | Distal (>10kb) Multiome | 824 | |
| chr19:12,550,951–12,551,971 | 150.3 kb | Distal (>10kb) Multiome | 976 | |
| chr19:12,610,516–12,611,613 | 209.6 kb | Distal (>10kb) Multiome | 925 | |
| chr19:12,639,899–12,640,614 | 239.0 kb | Distal (>10kb) Multiome | 454 | |
| chr19:12,647,538–12,648,022 | 246.5 kb | Distal (>10kb) Multiome | 126 | |
| chr19:12,656,871–12,657,566 | 256.0 kb | Distal (>10kb) Multiome | 254 | |
| chr19:12,666,317–12,667,225 | 265.5 kb | Distal (>10kb) Multiome | 495 | |
| chr19:12,681,003–12,682,117 | 280.1 kb | Distal (>10kb) Multiome | 994 | |
| chr19:12,696,035–12,696,970 | 295.3 kb | Distal (>10kb) Multiome | 806 |
Genomic view of the ZNF799 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.