chr2:37,443,019–37,443,805

chr2 : 37,443,019 – 37,443,805

786 bp 55 TFs 7 linked genes

This 786 bp open chromatin element is linked to 7 target genes and is bound by 55 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
QPCT		98.7 kb	Distal	Multiome
PRKD3		118.6 kb	Distal	Multiome
NDUFAF7		211.8 kb	Distal	Multiome
CEBPZ		211.8 kb	Distal	Multiome
CDC42EP3		228.2 kb	Distal	Multiome
CEBPZOS		246.9 kb	Distal	Multiome
EIF2AK2		286.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 229 bp overlap

BHLHE41 3 datasets

Motif DE_48h DE_48h-BHLHE41_MA0636.1 10 bp overlap

Motif DE_60h DE_60h-BHLHE41_MA0636.1 10 bp overlap

Motif DE_72h DE_72h-BHLHE41_MA0636.1 10 bp overlap

CASZ1 1 dataset

ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 244 bp overlap

CREBBP_M768 1 dataset

ChIP NCI-H3396_E2 GSE32349.CREBBP_M768.NCI-H3396_E2 96 bp overlap

ChIP GM20000 ENCFF217HWJ 165 bp overlap

DMRTC2 3 datasets

Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap

Motif DE_60h DE_60h-DMRTC2_MA1479.2 11 bp overlap

Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap

ChIP ProEs GSE59087.EED.ProEs 141 bp overlap

EGR4 2 datasets

Motif DE_60h DE_60h-EGR4_MA0733.2 11 bp overlap

Motif DE_72h DE_72h-EGR4_MA0733.2 11 bp overlap

EOMES 4 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 228 bp overlap

ChIP hESC GSE26097.EOMES.hESC 332 bp overlap

ERF::FOXO1 3 datasets

Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap

Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap

Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 2 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 190 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 65 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 786 bp overlap

ChIP DE DE-FOXA2-2 786 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 786 bp overlap

ChIP DE DE-GATA4-2 786 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 311 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 263 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 358 bp overlap

GATA6 14 datasets

ChIP AGS GSE51705.GATA6.AGS 132 bp overlap

ChIP DE DE-GATA6-1 786 bp overlap

ChIP DE DE-GATA6-2 786 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 786 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 786 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 664 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 786 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 786 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 786 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 765 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 322 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 274 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 335 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 351 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

MEIS1 3 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 2 datasets

Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

MITF 8 datasets

ChIP 501-mel GSE137522.MITF.501-mel 430 bp overlap

ChIP 501-mel GSE61965.MITF.501-mel 286 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 360 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 322 bp overlap

Motif DE_48h DE_48h-MITF_MA0620.4 10 bp overlap

Motif DE_60h DE_60h-MITF_MA0620.4 10 bp overlap

Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap

ChIP K-562 ENCSR797SWM.MITF.K-562 239 bp overlap

MXI1 3 datasets

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

MYOD1 1 dataset

ChIP RH4 GSE83726.MYOD1.RH4 169 bp overlap

Msgn1 2 datasets

Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap

Motif DE_72h DE_72h-Msgn1_MA1524.3 10 bp overlap

NR1H2::RXRA 3 datasets

Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap

Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap

Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2F1 3 datasets

Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap

Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap

Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap

Rarg 3 datasets

Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap

Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap

Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 786 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 643 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 536 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 727 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 715 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 313 bp overlap

SOX10 2 datasets

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX15 3 datasets

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap

Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 478 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 628 bp overlap

SOX4 2 datasets

Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

SREBF2 5 datasets

Motif DE_48h DE_48h-SREBF2_MA0828.3 10 bp overlap

Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap

Motif DE_60h DE_60h-SREBF2_MA0828.3 10 bp overlap

Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap

Motif DE_72h DE_72h-SREBF2_MA0828.3 10 bp overlap

Motif DE_48h DE_48h-SRF_MA0083.3 16 bp overlap

Motif DE_60h DE_60h-SRF_MA0083.3 16 bp overlap

Motif DE_72h DE_72h-SRF_MA0083.3 16 bp overlap

Stat2 3 datasets

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TBR1 2 datasets

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX18 2 datasets

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TBX2 2 datasets

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 2 datasets

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 2 datasets

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

TBX3 2 datasets

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TFE3 4 datasets

Motif DE_48h DE_48h-TFE3_MA0831.3 10 bp overlap

Motif DE_60h DE_60h-TFE3_MA0831.3 10 bp overlap

Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap

ChIP K562 ENCFF697ABG 317 bp overlap

TFEB 3 datasets

Motif DE_48h DE_48h-TFEB_MA0692.2 8 bp overlap

Motif DE_60h DE_60h-TFEB_MA0692.2 8 bp overlap

Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap

TFEC 3 datasets

Motif DE_48h DE_48h-TFEC_MA0871.3 8 bp overlap

Motif DE_60h DE_60h-TFEC_MA0871.3 8 bp overlap

Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap

Tbx6 2 datasets

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

USF1 5 datasets

Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap

Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap

Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 111 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 164 bp overlap

USF2 3 datasets

Motif DE_48h DE_48h-USF2_MA0526.5 10 bp overlap

Motif DE_60h DE_60h-USF2_MA0526.5 10 bp overlap

Motif DE_72h DE_72h-USF2_MA0526.5 10 bp overlap

VEZF1 2 datasets

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

ZNF317 2 datasets

ChIP HEK293 GSE76494.ZNF317.HEK293 224 bp overlap

ChIP WTC11 ENCFF537KXI 357 bp overlap

ZNF530 3 datasets

Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap

Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF677 3 datasets

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap

ZNF740 2 datasets

Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap

Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap