chr15 : 45,585,157 – 45,585,433

276 bp 53 TFs 2 linked genes

This 276 bp open chromatin element is linked to ENSG00000260170 and BLOC1S6 and is bound by 53 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000260170		1.9 kb	Proximal	Proximity
BLOC1S6		1.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

53 transcription factors

BHLHE40 2 datasets

ChIP GM12878 ENCFF521IZR 276 bp overlap

ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 230 bp overlap

CDX1 1 dataset

Motif DE_24h DE_24h-CDX1_MA0878.3 10 bp overlap

CDX4 1 dataset

Motif DE_24h DE_24h-CDX4_MA1473.2 9 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 143 bp overlap

DUXA 1 dataset

Motif DE_24h DE_24h-DUXA_MA0884.2 13 bp overlap

E2F6 1 dataset

Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 236 bp overlap

ETV5::DRGX 1 dataset

Motif DE_24h DE_24h-ETV5DRGX_MA1944.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_24h DE_24h-EWSR1-FLI1_MA0149.1 18 bp overlap

GATA1::TAL1 1 dataset

Motif DE_24h DE_24h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 276 bp overlap

ChIP DE DE-GATA4-2 276 bp overlap

Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 275 bp overlap

ChIP DE DE-GATA6-2 276 bp overlap

Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 276 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 276 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 276 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 276 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 276 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 276 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 276 bp overlap

Gata3 1 dataset

Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap

HOXA10 1 dataset

Motif DE_24h DE_24h-HOXA10_MA0899.2 9 bp overlap

HOXB13 1 dataset

Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap

HOXD9 1 dataset

Motif DE_24h DE_24h-HOXD9_MA0913.3 9 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_24h DE_24h-Hand1Tcf3_MA0092.2 9 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 260 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 194 bp overlap

NFIB 1 dataset

Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 185 bp overlap

NFKB2 1 dataset

ChIP L1236 GSE63736.NFKB2.L1236 180 bp overlap

Nr5A2 1 dataset

Motif DE_24h DE_24h-Nr5A2_MA0505.3 9 bp overlap

POU1F1 1 dataset

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_24h DE_24h-POU3F4_MA0789.1 9 bp overlap

POU4F1 1 dataset

Motif DE_24h DE_24h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_24h DE_24h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_24h DE_24h-POU4F3_MA0791.2 12 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 240 bp overlap

POU5F1B 1 dataset

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 247 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm15 1 dataset

Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap

RELA 1 dataset

ChIP LNCaP_SIFOXA1_TNFA GSE83860.RELA.LNCaP_SIFOXA1_TNFA 144 bp overlap

RELB 3 datasets

ChIP GM12878 ENCFF217ADF 276 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 252 bp overlap

REST 1 dataset

Motif DE_24h DE_24h-REST_MA0138.3 20 bp overlap

SKIL 3 datasets

ChIP GM12878 ENCFF171OVM 270 bp overlap

ChIP GM12878 ENCFF171OVM 199 bp overlap

ChIP GM12878 ENCSR212YKD.SKIL.GM12878 276 bp overlap

SMAD2 1 dataset

Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 276 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 276 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 276 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 255 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 276 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 276 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 276 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 276 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 276 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 190 bp overlap

TCF7L1 1 dataset

Motif DE_24h DE_24h-TCF7L1_MA1421.1 12 bp overlap

TRPS1 1 dataset

Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap