Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

47 transcription factors

BRD3 1 dataset

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 176 bp overlap

BRD4 1 dataset

ChIP COLO-741 GSE73319.BRD4.COLO-741 210 bp overlap

CBFA2T2 1 dataset

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 218 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 338 bp overlap

ChIP K562 ENCFF673OEZ 171 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 180 bp overlap

Crx 1 dataset

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 159 bp overlap

ESR1 3 datasets

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 269 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 210 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 260 bp overlap

FLI1 1 dataset

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 83 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 135 bp overlap

GATA1 4 datasets

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 110 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 273 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 197 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 159 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 509 bp overlap

ChIP DE DE-GATA4-2 518 bp overlap

ChIP foregut GSE117136.GATA4.foregut 382 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 418 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 463 bp overlap

ChIP DE DE-GATA6-2 479 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 518 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 518 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 518 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 477 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 518 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 518 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 392 bp overlap

ChIP foregut GSE117136.GATA6.foregut 388 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 111 bp overlap

GSC 1 dataset

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

GTF2I 1 dataset

ChIP WTC11 ENCFF255XXZ 253 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 252 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 208 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 364 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 494 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 383 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 156 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 336 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 255 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 198 bp overlap

NCAPH2 2 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 484 bp overlap

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 376 bp overlap

NFYB 1 dataset

Motif DE_36h DE_36h-NFYB_MA0502.3 9 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 120 bp overlap

OTX1 1 dataset

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

POU5F1 5 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 314 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 360 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 200 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 240 bp overlap

RHOXF1 1 dataset

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

SMAD1 1 dataset

ChIP CD34_ERYTH_BMP GSE29194.SMAD1.CD34_ERYTH_BMP 132 bp overlap

SMAD2-3 4 datasets

ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 113 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 304 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 431 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 175 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 362 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 320 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 281 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 236 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 266 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 271 bp overlap

SP5 1 dataset

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

TAL1 5 datasets

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 110 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 178 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 223 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 205 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 238 bp overlap

TP53 1 dataset

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 255 bp overlap

VDR 4 datasets

ChIP LNCaP GSE64656.VDR.LNCaP 192 bp overlap

ChIP LX2_CALCIPOTRIOL_TGFB1 GSE38103.VDR.LX2_CALCIPOTRIOL_TGFB1 141 bp overlap

ChIP THP-1_1d_1-25-OH-2D3 GSE89431.VDR.THP-1_1d_1-25-OH-2D3 318 bp overlap

ChIP THP-1_EtOH_1d GSE89431.VDR.THP-1_EtOH_1d 263 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 132 bp overlap

ZFP14 1 dataset

Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 207 bp overlap

ZNF135 1 dataset

Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap

ZNF460 1 dataset

Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 210 bp overlap

Zfp809 1 dataset

Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap

Genome Browser