Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

ASCL1 1 dataset

Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap

DUX4 2 datasets

Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap

Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap

Dux 2 datasets

Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap

Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 341 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 208 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 317 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 318 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 424 bp overlap

ChIP DE DE-GATA4-2 428 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 407 bp overlap

ChIP DE DE-GATA6-2 429 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 314 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 429 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 334 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 403 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 429 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 330 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 426 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 414 bp overlap

HES6 1 dataset

Motif DE_48h DE_48h-HES6_MA1493.1 10 bp overlap

HOXB4 2 datasets

Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap

Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap

Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap

HOXD4 2 datasets

Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap

Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap

IRF2 1 dataset

Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap

IRF3 1 dataset

Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap

MAX 1 dataset

ChIP WA01 ENCSR000EUP.MAX.WA01 161 bp overlap

MGA::EVX1 2 datasets

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap

MXI1 2 datasets

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 332 bp overlap

ChIP hESC GSE18292.NANOG.hESC 99 bp overlap

NKX6-3 2 datasets

Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap

Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap

POU6F1 2 datasets

Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap

Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap

POU6F2 2 datasets

Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap

Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap

Ptf1A 1 dataset

Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 205 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 306 bp overlap

RBPJ 2 datasets

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 297 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 239 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 358 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 186 bp overlap

SNAI1 1 dataset

Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap

SNAI3 1 dataset

Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 316 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 320 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 322 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 135 bp overlap

STAT1 2 datasets

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

Motif DE_60h DE_60h-STAT1_MA0137.4 9 bp overlap

STAT3 2 datasets

Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap

Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap

Sox11 1 dataset

Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap

Sox6 1 dataset

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

Stat2 2 datasets

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

Stat4 2 datasets

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Motif DE_60h DE_60h-Stat4_MA0518.2 10 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_60h DE_60h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap

Motif DE_60h DE_60h-Stat5b_MA1625.2 9 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 249 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 262 bp overlap

TCF12 2 datasets

Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 123 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 175 bp overlap

TCF3 1 dataset

Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap

TCF4 1 dataset

Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap

TFAP4 2 datasets

Motif DE_48h DE_48h-TFAP4_MA1570.1 10 bp overlap

Motif DE_60h DE_60h-TFAP4_MA1570.1 10 bp overlap

USF1 4 datasets

Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap

Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap

ChIP H1 ENCFF090WVU 238 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 274 bp overlap

ZEB1 1 dataset

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF24 2 datasets

Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap

Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap

ZNF341 1 dataset

Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap

ZNF354A 2 datasets

Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap

Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap

ZNF701 1 dataset

Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap

ZNF707 2 datasets

Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap

Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap

ZNF75D 1 dataset

Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap

Zfp335 2 datasets

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap

Genome Browser