chr3 : 120,028,696 – 120,029,024

328 bp 52 TFs 1 linked gene

This 328 bp open chromatin element is linked to PARLP1 and is bound by 52 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PARLP1		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

AR 2 datasets

ChIP MCF-7 GSE48930.AR.MCF-7 232 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 176 bp overlap

ASCL1 1 dataset

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

Ahr::Arnt 1 dataset

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD4 1 dataset

ChIP IMR-90_SENES GSE74238.BRD4.IMR-90_SENES 200 bp overlap

CBFB 2 datasets

ChIP ME-1 GSE46044.CBFB.ME-1 202 bp overlap

ChIP SKNO-1 GSE23730.CBFB.SKNO-1 197 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 180 bp overlap

CTCF 2 datasets

Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 187 bp overlap

ERF::NHLH1 1 dataset

Motif DE_12h DE_12h-ERFNHLH1_MA1938.2 16 bp overlap

ERG 3 datasets

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 192 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 209 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 195 bp overlap

ESR1 1 dataset

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 235 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

EZH2 1 dataset

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 133 bp overlap

FLI1 2 datasets

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 237 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 237 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 176 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-2 90 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

ISL1 1 dataset

ChIP Huh-7 GSE77957.ISL1.Huh-7 92 bp overlap

KLF3 1 dataset

Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 210 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 199 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 325 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 215 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 306 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 126 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

RXR 1 dataset

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 228 bp overlap

SMAD2 3 datasets

ChIP hESC GSE29422.SMAD2.hESC 229 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 328 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 269 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 328 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 328 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 328 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 328 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 328 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 281 bp overlap

SMAD3 1 dataset

ChIP hESC GSE29422.SMAD3.hESC 152 bp overlap

SMAD4 1 dataset

ChIP hESC GSE29422.SMAD4.hESC 137 bp overlap

SMARCA4 1 dataset

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 67 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 175 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 220 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

ZBED4 1 dataset

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 209 bp overlap

ZEB1 1 dataset

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 125 bp overlap

ZNF214 1 dataset

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 143 bp overlap

ZNF519 1 dataset

ChIP HEK293T GSE78099.ZNF519.HEK293T 162 bp overlap

ZNF530 1 dataset

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap