chr3 : 69,659,258 – 69,659,932
674 bp 65 TFs 1 linked gene
This 674 bp open chromatin element is linked to FRMD4B and is bound by 65 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FRMD4B 116.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:69,654,258 – 69,664,932
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
65 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP GSE80256.AR.LNCaP 184 bp overlap
Atoh1 2 datasets
Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap
Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap
BRF1 1 dataset
ChIP H9_Activin GSE94418.BRF1.H9_Activin 148 bp overlap
CBFA2T3 1 dataset
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 200 bp overlap
CHD2 1 dataset
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 210 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF335XTP 281 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 216 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 604 bp overlap
EP300 2 datasets
ChIP SK-N-SH ENCFF829RWA 291 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 252 bp overlap
ERG 1 dataset
ChIP VCaP GSE49091.ERG.VCaP 135 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 200 bp overlap
FOS 2 datasets
Motif DE_48h DE_48h-FOS_MA1951.2 13 bp overlap
Motif DE_60h DE_60h-FOS_MA1951.2 13 bp overlap
FOSB::JUN 2 datasets
Motif DE_48h DE_48h-FOSBJUN_MA1127.1 11 bp overlap
Motif DE_60h DE_60h-FOSBJUN_MA1127.1 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 674 bp overlap
ChIP DE DE-FOXA2-2 674 bp overlap
GATA1 5 datasets
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 156 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 192 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 148 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 337 bp overlap
GATA1::TAL1 2 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 7 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 283 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP SH-SY5Y ENCFF485YIB 221 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 350 bp overlap
ChIP SK-N-SH ENCFF764OZD 204 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 248 bp overlap
GATA3 7 datasets
ChIP BE2C GSE65664.GATA3.BE2C 180 bp overlap
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 268 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 146 bp overlap
ChIP SH-SY5Y ENCFF475HYF 334 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 261 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 203 bp overlap
ChIP SK-N-SH ENCFF040SSB 120 bp overlap
GATA4 11 datasets
ChIP DE DE-GATA4-1 674 bp overlap
ChIP DE DE-GATA4-2 674 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP G296S GSE85628.GATA4.G296S 188 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 188 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 281 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 258 bp overlap
ChIP foregut GSE117136.GATA4.foregut 318 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 271 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 235 bp overlap
GATA5 4 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 280 bp overlap
ChIP AGS GSE51936.GATA6.AGS 91 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 205 bp overlap
ChIP DE DE-GATA6-1 674 bp overlap
ChIP DE DE-GATA6-2 674 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 224 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 269 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 674 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 302 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 392 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 674 bp overlap
ChIP foregut GSE117136.GATA6.foregut 307 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 262 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 279 bp overlap
GRHL2 2 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Gata3 4 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 4 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 228 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 257 bp overlap
HNF4A 2 datasets
Motif DE_48h DE_48h-HNF4A_MA0114.5 9 bp overlap
Motif DE_60h DE_60h-HNF4A_MA0114.5 9 bp overlap
HNF4G 2 datasets
Motif DE_48h DE_48h-HNF4G_MA0484.3 9 bp overlap
Motif DE_60h DE_60h-HNF4G_MA0484.3 9 bp overlap
Hoxd13 2 datasets
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_60h DE_60h-Hoxd13_MA0909.4 7 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 232 bp overlap
KDM1A 2 datasets
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 235 bp overlap
ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 224 bp overlap
KLF17 2 datasets
Motif DE_48h DE_48h-KLF17_MA1514.2 14 bp overlap
Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap
LDB1 1 dataset
ChIP HEP GSE52637.LDB1.HEP 196 bp overlap
LIN54 2 datasets
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
NEUROD1 4 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 186 bp overlap
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 122 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 2 datasets
Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 274 bp overlap
NKX2-5 2 datasets
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 395 bp overlap
ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 198 bp overlap
NR2C2 2 datasets
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
Neurod2 2 datasets
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Nr2e1 2 datasets
Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 275 bp overlap
PGR 1 dataset
ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 331 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 225 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 361 bp overlap
Pparg::Rxra 2 datasets
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
RCOR1 2 datasets
ChIP SK-N-SH ENCFF518EXB 192 bp overlap
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 282 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 672 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 674 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 674 bp overlap
SMARCA4 1 dataset
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 299 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 441 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 674 bp overlap
SPIC 2 datasets
Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap
Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap
Spz1 2 datasets
Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap
Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap
TAL1 4 datasets
ChIP CD34 GSE52924.TAL1.CD34 150 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 159 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 142 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 234 bp overlap
TCF4 2 datasets
ChIP SH-SY5Y GSE96915.TCF4.SH-SY5Y 243 bp overlap
ChIP SK-N-SH ENCFF270OWF 192 bp overlap
TFAP2B 1 dataset
ChIP SK-N-SH ENCFF869XXQ 312 bp overlap
TOX2 2 datasets
ChIP SK-N-SH ENCFF415OYE 231 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR226NRS.TOX2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 180 bp overlap
TRPS1 4 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 201 bp overlap
TWIST1 2 datasets
Motif DE_48h DE_48h-TWIST1_MA1123.3 8 bp overlap
Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap
XRCC5 1 dataset
ChIP K-562 GSE120104.XRCC5.K-562 146 bp overlap
ZBTB26 2 datasets
Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB26_MA1579.2 8 bp overlap
ZFP42 2 datasets
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
ZNF416 2 datasets
Motif DE_48h DE_48h-ZNF416_MA1979.2 10 bp overlap
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
ZNF652 2 datasets
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
Zfp809 2 datasets
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
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