chr2 : 84,461,804 – 84,462,404

600 bp 54 TFs 2 linked genes

This 600 bp open chromatin element is linked to ENSG00000289076 and SUCLG1 and is bound by 54 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000289076		2.2 kb	Proximal	Proximity
SUCLG1		2.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

54 transcription factors

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF1 4 datasets

ChIP Hep-G2 ENCSR000BMZ.ELF1.Hep-G2 105 bp overlap

ChIP Hep-G2 ENCSR321VGW.ELF1.Hep-G2 103 bp overlap

ChIP HepG2 ENCFF367ZWV 257 bp overlap

ChIP HepG2 ENCFF838BCU 176 bp overlap

ELF3 1 dataset

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ERF 1 dataset

Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ETS1 1 dataset

Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ETV2 1 dataset

Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FIGLA 2 datasets

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

FLI1 1 dataset

Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 362 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 594 bp overlap

ChIP DE DE-GATA4-2 593 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 600 bp overlap

ChIP DE DE-GATA6-2 600 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 600 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 600 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 600 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 558 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 600 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 600 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 175 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 584 bp overlap

HAND2 2 datasets

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 548 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 438 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 384 bp overlap

MYOD1 2 datasets

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

Motif DE_24h DE_24h-MYOD1_MA0499.3 9 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 233 bp overlap

NEUROD1 2 datasets

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

Motif DE_24h DE_24h-NEUROD1_MA1109.2 8 bp overlap

NHLH2 2 datasets

Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap

Motif DE_24h DE_24h-NHLH2_MA1529.2 16 bp overlap

Nanog 2 datasets

Motif DE_12h DE_12h-Nanog_MA2339.1 7 bp overlap

Motif DE_24h DE_24h-Nanog_MA2339.1 7 bp overlap

Neurod2 2 datasets

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

Motif DE_24h DE_24h-Neurod2_MA0668.3 8 bp overlap

ONECUT1 2 datasets

ChIP Hep-G2 ENCSR956OSX.ONECUT1.Hep-G2 133 bp overlap

ChIP HepG2 ENCFF243FIR 115 bp overlap

ONECUT2 1 dataset

ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 122 bp overlap

POU4F1 2 datasets

Motif DE_12h DE_12h-POU4F1_MA0790.2 12 bp overlap

Motif DE_24h DE_24h-POU4F1_MA0790.2 12 bp overlap

POU4F2 2 datasets

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

Motif DE_24h DE_24h-POU4F2_MA0683.2 15 bp overlap

POU4F3 2 datasets

Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap

Motif DE_24h DE_24h-POU4F3_MA0791.2 12 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 258 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 410 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 414 bp overlap

Ptf1A 2 datasets

Motif DE_12h DE_12h-Ptf1A_MA1618.2 9 bp overlap

Motif DE_24h DE_24h-Ptf1A_MA1618.2 9 bp overlap

RELA 1 dataset

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

SMAD2 2 datasets

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 600 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 495 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 600 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 600 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 600 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 600 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 600 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 600 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 600 bp overlap

SOX13 1 dataset

ChIP HepG2 ENCFF062VSQ 234 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 201 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 276 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SREBF1 2 datasets

Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap

Motif DE_24h DE_24h-SREBF1_MA0829.3 10 bp overlap

TEAD1 1 dataset

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Wt1 1 dataset

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

ZEB1 2 datasets

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

ZNF136 1 dataset

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF335 1 dataset

ChIP HepG2 ENCFF539IIQ 462 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap