chr13 : 100,736,518 – 100,737,276
758 bp 67 TFs 1 linked gene
This 758 bp open chromatin element is linked to TMTC4 and is bound by 67 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TMTC4 62.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr13:100,731,518 – 100,742,276
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
67 transcription factors
Source
Cell type
ATF4 1 dataset
Motif DE_72h DE_72h-ATF4_MA0833.3 10 bp overlap
BARHL1 3 datasets
Motif DE_48h DE_48h-BARHL1_MA0877.4 6 bp overlap
Motif DE_60h DE_60h-BARHL1_MA0877.4 6 bp overlap
Motif DE_72h DE_72h-BARHL1_MA0877.4 6 bp overlap
BARHL2 3 datasets
Motif DE_48h DE_48h-BARHL2_MA0635.2 6 bp overlap
Motif DE_60h DE_60h-BARHL2_MA0635.2 6 bp overlap
Motif DE_72h DE_72h-BARHL2_MA0635.2 6 bp overlap
BHLHE22 3 datasets
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
Bach1::Mafk 3 datasets
Motif DE_48h DE_48h-Bach1Mafk_MA0591.2 12 bp overlap
Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap
Motif DE_72h DE_72h-Bach1Mafk_MA0591.2 12 bp overlap
Bcl11B 3 datasets
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CEBPB 1 dataset
ChIP Hep-G2 ENCSR000BQI.CEBPB.Hep-G2 100 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 363 bp overlap
ETV2::DRGX 1 dataset
Motif DE_72h DE_72h-ETV2DRGX_MA1940.2 12 bp overlap
ETV5::DRGX 1 dataset
Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::HOXA2 1 dataset
Motif DE_72h DE_72h-ETV5HOXA2_MA1948.2 12 bp overlap
FLI1::DRGX 1 dataset
Motif DE_72h DE_72h-FLI1DRGX_MA1949.2 14 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 758 bp overlap
ChIP DE DE-FOXA2-2 693 bp overlap
GATA2 2 datasets
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 758 bp overlap
ChIP DE DE-GATA4-2 739 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 603 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 497 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 266 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 64 bp overlap
GATA6 12 datasets
ChIP AGS GSE51705.GATA6.AGS 224 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 239 bp overlap
ChIP DE DE-GATA6-1 754 bp overlap
ChIP DE DE-GATA6-2 758 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 758 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 530 bp overlap
ChIP foregut GSE117136.GATA6.foregut 578 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 279 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 401 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 293 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HOXB4 3 datasets
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 3 datasets
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 3 datasets
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
HSF1 3 datasets
Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap
Motif DE_60h DE_60h-HSF1_MA0486.2 13 bp overlap
Motif DE_72h DE_72h-HSF1_MA0486.2 13 bp overlap
HSF4 3 datasets
Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap
Motif DE_60h DE_60h-HSF4_MA0771.1 13 bp overlap
Motif DE_72h DE_72h-HSF4_MA0771.1 13 bp overlap
IKZF2 2 datasets
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
INSM1 2 datasets
Motif DE_60h DE_60h-INSM1_MA0155.1 12 bp overlap
Motif DE_72h DE_72h-INSM1_MA0155.1 12 bp overlap
IRF2 3 datasets
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
Motif DE_72h DE_72h-IRF2_MA0051.2 16 bp overlap
Irf1 3 datasets
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
MAF 3 datasets
Motif DE_48h DE_48h-MAF_MA1520.2 13 bp overlap
Motif DE_60h DE_60h-MAF_MA1520.2 13 bp overlap
Motif DE_72h DE_72h-MAF_MA1520.2 13 bp overlap
MAFA 3 datasets
Motif DE_48h DE_48h-MAFA_MA1521.2 13 bp overlap
Motif DE_60h DE_60h-MAFA_MA1521.2 13 bp overlap
Motif DE_72h DE_72h-MAFA_MA1521.2 13 bp overlap
MAFG::NFE2L1 3 datasets
Motif DE_48h DE_48h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_60h DE_60h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap
MAFK 3 datasets
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap
MEF2C 2 datasets
Motif DE_60h DE_60h-MEF2C_MA0497.2 11 bp overlap
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MGA::EVX1 3 datasets
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
MTF1 2 datasets
Motif DE_48h DE_48h-MTF1_MA0863.1 14 bp overlap
Motif DE_60h DE_60h-MTF1_MA0863.1 14 bp overlap
MXI1 2 datasets
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
Mafg 3 datasets
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap
Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap
NFATC3 3 datasets
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NKX2-2 2 datasets
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
Neurod2 3 datasets
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
Nfat5 6 datasets
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 3 datasets
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 3 datasets
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap
Olig2 3 datasets
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
PBX3 2 datasets
Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap
Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap
RUNX2 3 datasets
Motif DE_48h DE_48h-RUNX2_MA0511.2 9 bp overlap
Motif DE_60h DE_60h-RUNX2_MA0511.2 9 bp overlap
Motif DE_72h DE_72h-RUNX2_MA0511.2 9 bp overlap
RUNX3 3 datasets
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
Runx1 5 datasets
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap
Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 637 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 270 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 512 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 325 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 536 bp overlap
SREBF1 3 datasets
Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap
Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap
Sox11 2 datasets
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 217 bp overlap
TCF7L1 2 datasets
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TFAP4 3 datasets
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap
TRPS1 2 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Tcf12 3 datasets
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Twist2 3 datasets
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
ZBTB33 1 dataset
ChIP HepG2 ENCFF778UKV 208 bp overlap
ZNF418 2 datasets
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
ZNF449 2 datasets
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap
ZNF454 1 dataset
Motif DE_60h DE_60h-ZNF454_MA1712.2 17 bp overlap
ZNF680 3 datasets
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF766 3 datasets
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
ZNF85 2 datasets
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap
ZSCAN21 1 dataset
Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap
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