chr12 : 19,166,948 – 19,167,262

314 bp 58 TFs 1 linked gene

This 314 bp open chromatin element is linked to RN7SL459P and is bound by 58 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
RN7SL459P		9.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 232 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 194 bp overlap

EOMES 2 datasets

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 285 bp overlap

ESR1 1 dataset

ChIP Ishikawa_C1-5 GSE147141.ESR1.Ishikawa_C1-5 211 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 293 bp overlap

FOXA1 1 dataset

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 151 bp overlap

FOXA2 5 datasets

ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 146 bp overlap

ChIP DE DE-FOXA2-1 314 bp overlap

ChIP DE DE-FOXA2-2 314 bp overlap

Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap

Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap

FOXA3 2 datasets

Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap

Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap

FOXC2 2 datasets

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXD3 2 datasets

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

FOXF2 2 datasets

Motif DE_12h DE_12h-FOXF2_MA0030.2 9 bp overlap

Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap

FOXI1 2 datasets

Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap

Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap

FOXN3 2 datasets

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap

FOXP1 2 datasets

Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap

Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap

FOXP4 2 datasets

Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap

Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap

Foxj3 2 datasets

Motif DE_12h DE_12h-Foxj3_MA0851.2 9 bp overlap

Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 160 bp overlap

ChIP DE DE-GATA4-1 314 bp overlap

ChIP DE DE-GATA4-2 314 bp overlap

ChIP foregut GSE117136.GATA4.foregut 314 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 314 bp overlap

ChIP DE DE-GATA6-2 314 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 287 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 256 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 304 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 314 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 280 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 307 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HNF4A 1 dataset

ChIP liver ENCFF449HPV 58 bp overlap

HOXB4 3 datasets

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap

HOXC4 3 datasets

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap

HOXD4 3 datasets

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

KLF4 2 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 151 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 265 bp overlap

NANOG 1 dataset

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 188 bp overlap

NEUROD1 1 dataset

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 179 bp overlap

NKX2-4 1 dataset

Motif DE_12h DE_12h-NKX2-4_MA2003.2 8 bp overlap

NKX6-3 2 datasets

Motif DE_12h DE_12h-NKX6-3_MA1530.2 8 bp overlap

Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU6F1 2 datasets

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap

POU6F2 3 datasets

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap

PRDM4 1 dataset

ChIP HEK293 ENCFF069PHD 210 bp overlap

PRDM9 2 datasets

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 314 bp overlap

SCRT1 1 dataset

Motif DE_12h DE_12h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_12h DE_12h-SCRT2_MA0744.3 10 bp overlap

SIX2 1 dataset

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 164 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 256 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 222 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 243 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 288 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 235 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 192 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 287 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 306 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 100 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 269 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

ZBTB6 1 dataset

ChIP HEK293 GSE76494.ZBTB6.HEK293 142 bp overlap

ZNF320 2 datasets

Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap

Motif DE_48h DE_48h-ZNF320_MA1976.2 20 bp overlap

ZNF652 1 dataset

Motif DE_12h DE_12h-ZNF652_MA1657.2 9 bp overlap

ZNF680 1 dataset

ChIP HEK293 GSE76494.ZNF680.HEK293 181 bp overlap

ZSCAN31 1 dataset

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap