chr11 : 44,496,366 – 44,496,899

533 bp 57 TFs 1 linked gene

This 533 bp open chromatin element is linked to TSPAN18 and is bound by 57 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TSPAN18		230.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

57 transcription factors

BMPR1A 1 dataset

ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 237 bp overlap

CHD8 1 dataset

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 157 bp overlap

CRX 3 datasets

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 178 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 284 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 290 bp overlap

CTCF 1 dataset

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 193 bp overlap

CTCFL 2 datasets

Motif DE_48h DE_48h-CTCFL_MA1102.3 8 bp overlap

Motif DE_60h DE_60h-CTCFL_MA1102.3 8 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DUX4 2 datasets

ChIP HEK293 GSE75791.DUX4.HEK293 235 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 290 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 410 bp overlap

ESR1 1 dataset

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 236 bp overlap

FIGLA 2 datasets

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 212 bp overlap

ChIP DE DE-FOXA2-1 456 bp overlap

ChIP DE DE-FOXA2-2 466 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 175 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 490 bp overlap

ChIP DE DE-GATA4-2 510 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 457 bp overlap

ChIP DE DE-GATA6-2 533 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 375 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 458 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 469 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 472 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 417 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 441 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 439 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

MAZ 2 datasets

Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap

Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap

MEF2D 1 dataset

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 236 bp overlap

MYOD1 2 datasets

Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

MZF1 1 dataset

Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap

NANOG 1 dataset

ChIP WA01 ENCSR000BMT.NANOG.WA01 167 bp overlap

NEUROD1 4 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 421 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 341 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 201 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 165 bp overlap

OLIG1 1 dataset

Motif DE_60h DE_60h-OLIG1_MA0826.1 10 bp overlap

OLIG2 1 dataset

Motif DE_60h DE_60h-OLIG2_MA0678.1 10 bp overlap

OLIG3 1 dataset

Motif DE_60h DE_60h-OLIG3_MA0827.1 10 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 311 bp overlap

PATZ1 2 datasets

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 89 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

Ptf1A 2 datasets

Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

RORB 1 dataset

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 240 bp overlap

SCRT1 2 datasets

Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap

Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap

SCRT2 2 datasets

Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap

Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap

SIX1 1 dataset

Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap

SIX2 1 dataset

Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 460 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 347 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 401 bp overlap

SNAI2 2 datasets

Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap

Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 252 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 399 bp overlap

Six4 1 dataset

Motif DE_60h DE_60h-Six4_MA2001.2 7 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 291 bp overlap

TP63 1 dataset

ChIP breast-organoid GSE113909.TP63.breast-organoid 116 bp overlap

ZBTB12 1 dataset

Motif DE_60h DE_60h-ZBTB12_MA1649.2 7 bp overlap

ZEB1 2 datasets

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZNF148 2 datasets

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

ZNF257 2 datasets

Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap

Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 102 bp overlap

ZNF281 2 datasets

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

ZNF320 1 dataset

Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap

ZNF460 1 dataset

Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap

ZNF768 1 dataset

Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap