chr8 : 6,553,721 – 6,554,476
755 bp 42 TFs 1 linked gene
This 755 bp open chromatin element is linked to ANGPT2 and is bound by 42 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ANGPT2 8.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:6,548,721 – 6,559,476
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
42 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP RMG-I GSE104545.ARID1A.RMG-I 213 bp overlap
Arid3a 2 datasets
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
CREBBP_M768 1 dataset
ChIP NCI-H3396_ETOH GSE32349.CREBBP_M768.NCI-H3396_ETOH 89 bp overlap
Dux 2 datasets
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap
EOMES 2 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 350 bp overlap
FIGLA 2 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 488 bp overlap
ChIP DE DE-FOXA2-2 545 bp overlap
GATA4 7 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 188 bp overlap
ChIP DE DE-GATA4-1 560 bp overlap
ChIP DE DE-GATA4-2 654 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 614 bp overlap
ChIP DE DE-GATA6-2 610 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 603 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 609 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 592 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 670 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 618 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 680 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 626 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Gli1 2 datasets
Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Gli2 2 datasets
Motif DE_48h DE_48h-Gli2_MA0734.4 9 bp overlap
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
HIC2 1 dataset
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
ISL2 1 dataset
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap
MEF2B 1 dataset
Motif DE_60h DE_60h-MEF2B_MA0660.1 12 bp overlap
MEF2D 1 dataset
Motif DE_60h DE_60h-MEF2D_MA0773.1 12 bp overlap
MEIS1 1 dataset
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MGA 1 dataset
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Mecom 2 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Msgn1 1 dataset
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
POU3F3 1 dataset
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
SATB1 2 datasets
Motif DE_48h DE_48h-SATB1_MA1963.2 7 bp overlap
Motif DE_60h DE_60h-SATB1_MA1963.2 7 bp overlap
SMAD2-3 3 datasets
ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 182 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 354 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 303 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 569 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 290 bp overlap
SREBF1 2 datasets
Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap
SS18 1 dataset
ChIP SYO-1 GSE108025.SS18.SYO-1 387 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 257 bp overlap
TBR1 1 dataset
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
TBX4 1 dataset
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tfcp2l1 2 datasets
Motif DE_36h DE_36h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_60h DE_60h-Tfcp2l1_MA0145.2 14 bp overlap
ZEB1 2 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZKSCAN3 1 dataset
Motif DE_60h DE_60h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF16 2 datasets
Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap
Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap
ZNF211 2 datasets
Motif DE_48h DE_48h-ZNF211_MA1974.2 10 bp overlap
Motif DE_60h DE_60h-ZNF211_MA1974.2 10 bp overlap
ZNF22 1 dataset
ChIP HEK293 GSE76494.ZNF22.HEK293 174 bp overlap
ZNF320 1 dataset
ChIP HEK293 GSE76494.ZNF320.HEK293 119 bp overlap
ZNF675 1 dataset
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
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