Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

43 transcription factors

BRD4 2 datasets

ChIP MCF-10A ERP003925.BRD4.MCF-10A 53 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 124 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 205 bp overlap

CDK8 1 dataset

ChIP SW480 GSE53602.CDK8.SW480 213 bp overlap

DNMT3B 1 dataset

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 106 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 360 bp overlap

ChIP H1 ENCFF785DWK 153 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 535 bp overlap

ESR1 3 datasets

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 497 bp overlap

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 247 bp overlap

ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 380 bp overlap

EZH2 3 datasets

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 222 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 161 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 204 bp overlap

FOXA2 3 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 239 bp overlap

ChIP DE DE-FOXA2-1 438 bp overlap

ChIP DE DE-FOXA2-2 413 bp overlap

GATA2 5 datasets

ChIP K-562 ENCSR000EWG.GATA2.K-562 152 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 317 bp overlap

ChIP SH-SY5Y ENCFF485YIB 405 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 221 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

GATA3 1 dataset

ChIP NGP GSE65664.GATA3.NGP 154 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 208 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 503 bp overlap

ChIP DE DE-GATA4-2 506 bp overlap

ChIP foregut GSE117136.GATA4.foregut 359 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 390 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 440 bp overlap

GATA6 14 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 210 bp overlap

ChIP DE DE-GATA6-1 415 bp overlap

ChIP DE DE-GATA6-2 518 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 519 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 491 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 535 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 387 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 535 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 535 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 428 bp overlap

ChIP foregut GSE117136.GATA6.foregut 299 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 371 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 297 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 221 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 370 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 535 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 264 bp overlap

JUN 2 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 291 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 370 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 515 bp overlap

KMT2A 1 dataset

ChIP RS4-11_DMSO-D3-180402 GSE127507.KMT2A.RS4-11_DMSO-D3-180402 202 bp overlap

MAX 2 datasets

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 350 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 300 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 262 bp overlap

PATZ1 1 dataset

ChIP HepG2 ENCFF723PFC 401 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 221 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 483 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 457 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 327 bp overlap

RARA 1 dataset

ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 228 bp overlap

RELA 1 dataset

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 207 bp overlap

RNF2 1 dataset

ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 349 bp overlap

RXR 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 210 bp overlap

SIX2 3 datasets

ChIP HEK GSE73865.SIX2.HEK 333 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 304 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 274 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 460 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 486 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 535 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 415 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 397 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 457 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 284 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 233 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 535 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 443 bp overlap

SMC1 1 dataset

ChIP DKO GSE131606.SMC1.DKO 186 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 322 bp overlap

SS18 1 dataset

ChIP Aska-SS GSE108025.SS18.Aska-SS 241 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 360 bp overlap

TBX3 2 datasets

ChIP HepG2 ENCFF178RIL 397 bp overlap

ChIP HepG2 ENCFF178RIL 216 bp overlap

TCF7L2 4 datasets

ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 146 bp overlap

ChIP HCT-116_C16 GSE127960.TCF7L2.HCT-116_C16 209 bp overlap

ChIP PANC-1 ENCSR000EXL.TCF7L2.PANC-1 382 bp overlap

ChIP Panc1 ENCFF829HHL 462 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 210 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 83 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 303 bp overlap

Genome Browser