chr5 : 133,786,502 – 133,787,082
580 bp 59 TFs 3 linked genes
This 580 bp open chromatin element is linked to FSTL4, C5orf15, and VDAC1 and is bound by 59 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FSTL4 174.2 kb Distal Multiome
C5orf15 181.9 kb Distal Multiome
VDAC1 217.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:133,781,502 – 133,792,082
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
59 transcription factors
Source
Cell type
BCL6B 2 datasets
Motif DE_36h DE_36h-BCL6B_MA0731.1 17 bp overlap
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
CTCF 4 datasets
Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 331 bp overlap
EHF 1 dataset
Motif DE_36h DE_36h-EHF_MA0598.4 9 bp overlap
ELF1 1 dataset
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
ELF3 1 dataset
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 368 bp overlap
ETV5::DRGX 3 datasets
Motif DE_36h DE_36h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::HOXA2 3 datasets
Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_60h DE_60h-ETV5HOXA2_MA1948.2 12 bp overlap
ETV6 1 dataset
Motif DE_36h DE_36h-ETV6_MA0645.2 9 bp overlap
ETV7 1 dataset
Motif DE_36h DE_36h-ETV7_MA1708.2 9 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 1 dataset
ChIP A-1847 GSE95643.EZH2.A-1847 153 bp overlap
Elf5 1 dataset
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
Erg 1 dataset
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
FIGLA 2 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 541 bp overlap
ChIP DE DE-FOXA2-2 471 bp overlap
GABPA 1 dataset
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 544 bp overlap
ChIP DE DE-GATA4-2 547 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 515 bp overlap
ChIP DE DE-GATA6-2 533 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 256 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 547 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 367 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 479 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 562 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Gli1 2 datasets
Motif DE_36h DE_36h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Gli2 2 datasets
Motif DE_36h DE_36h-Gli2_MA0734.4 9 bp overlap
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
IKZF2 2 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
ISL2 3 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Ikzf3 1 dataset
Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap
MEIS1 3 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
NFKB1 1 dataset
ChIP L1236 GSE63736.NFKB1.L1236 170 bp overlap
NRL 3 datasets
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Nkx3-2 3 datasets
Motif DE_36h DE_36h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
POU2F1::SOX2 3 datasets
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
RARA 1 dataset
Motif DE_36h DE_36h-RARA_MA0730.1 17 bp overlap
RBPJ 2 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
RELA 10 datasets
ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 175 bp overlap
ChIP HUVEC-C_TNF GSE53998.RELA.HUVEC-C_TNF 209 bp overlap
ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 271 bp overlap
ChIP LNCaP_SIFOXA1_TNFA GSE83860.RELA.LNCaP_SIFOXA1_TNFA 215 bp overlap
ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 211 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 290 bp overlap
ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 226 bp overlap
ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 165 bp overlap
ChIP aortic-endothelial-cell_IL1B_D40 GSE139377.RELA.aortic-endothelial-cell_IL1B_D40 243 bp overlap
ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 186 bp overlap
RREB1 2 datasets
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
Rarb 1 dataset
Motif DE_36h DE_36h-Rarb_MA0858.1 17 bp overlap
SIX2 2 datasets
Motif DE_36h DE_36h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
SMAD2 3 datasets
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 428 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 464 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 560 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 322 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 372 bp overlap
SPIB 1 dataset
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
SREBF1 2 datasets
Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap
Spi1 1 dataset
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 275 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZBTB11 1 dataset
Motif DE_36h DE_36h-ZBTB11_MA2329.1 9 bp overlap
ZEB1 2 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZKSCAN5 1 dataset
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF175 1 dataset
Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap
ZNF382 3 datasets
Motif DE_36h DE_36h-ZNF382_MA1594.1 24 bp overlap
Motif DE_48h DE_48h-ZNF382_MA1594.1 24 bp overlap
Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap
ZNF528 1 dataset
Motif DE_36h DE_36h-ZNF528_MA1597.1 17 bp overlap
ZNF768 2 datasets
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
ZNF85 2 datasets
Motif DE_36h DE_36h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
ZSCAN21 3 datasets
Motif DE_36h DE_36h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_48h DE_48h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap
Zfp335 3 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
Zfp809 2 datasets
Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
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