chr3:170,817,407–170,818,229

chr3 : 170,817,407 – 170,818,229

822 bp 68 TFs 5 linked genes

This 822 bp open chromatin element is linked to 5 target genes and is bound by 68 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RPL22L1		52.4 kb	Distal	Multiome
EIF5A2		90.8 kb	Distal	Multiome
SLC7A14		231.7 kb	Distal	Multiome+HiCAR
SLC7A14-AS1		350.5 kb	Distal	Multiome+HiCAR
CLDN11		398.9 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

ChIP H-1_DE GSE126661.BRD3.H-1_DE 86 bp overlap

Motif DE_36h DE_36h-CDX2_MA0465.3 8 bp overlap

CTCF 3 datasets

Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap

Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap

Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 311 bp overlap

E2F7 4 datasets

Motif DE_36h DE_36h-E2F7_MA0758.1 14 bp overlap

Motif DE_48h DE_48h-E2F7_MA0758.1 14 bp overlap

Motif DE_60h DE_60h-E2F7_MA0758.1 14 bp overlap

Motif DE_72h DE_72h-E2F7_MA0758.1 14 bp overlap

E2F8 4 datasets

Motif DE_36h DE_36h-E2F8_MA0865.3 9 bp overlap

Motif DE_48h DE_48h-E2F8_MA0865.3 9 bp overlap

Motif DE_60h DE_60h-E2F8_MA0865.3 9 bp overlap

Motif DE_72h DE_72h-E2F8_MA0865.3 9 bp overlap

FEZF2 2 datasets

Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap

Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap

FIGLA 1 dataset

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 788 bp overlap

ChIP DE DE-FOXA2-2 794 bp overlap

FOXD2 1 dataset

Motif DE_36h DE_36h-FOXD2_MA0847.4 11 bp overlap

FOXF2 1 dataset

Motif DE_36h DE_36h-FOXF2_MA0030.2 9 bp overlap

FOXH1 1 dataset

Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap

FOXK1 1 dataset

Motif DE_36h DE_36h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_36h DE_36h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_36h DE_36h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_36h DE_36h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_36h DE_36h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_36h DE_36h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_36h DE_36h-Foxf1_MA1606.2 7 bp overlap

Foxo1 1 dataset

Motif DE_36h DE_36h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_36h DE_36h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_36h DE_36h-Foxq1_MA0040.2 10 bp overlap

GATA2 3 datasets

Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

GATA4 9 datasets

ChIP DE DE-GATA4-1 655 bp overlap

ChIP DE DE-GATA4-2 822 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

GATA5 3 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 737 bp overlap

ChIP DE DE-GATA6-2 822 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 726 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 822 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 822 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 822 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 443 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 444 bp overlap

Motif DE_36h DE_36h-GLI3_MA1491.3 15 bp overlap

GRHL2 1 dataset

Motif DE_36h DE_36h-GRHL2_MA1105.3 8 bp overlap

Gata3 3 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

Motif DE_36h DE_36h-Gli1_MA1990.2 10 bp overlap

Motif DE_36h DE_36h-Gli2_MA0734.4 9 bp overlap

HOXB13 4 datasets

Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap

Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap

Motif DE_60h DE_60h-HOXB13_MA0901.3 9 bp overlap

Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap

Hoxa13 4 datasets

Motif DE_36h DE_36h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_60h DE_60h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 614 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 788 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 731 bp overlap

KLF13 4 datasets

Motif DE_36h DE_36h-KLF13_MA0657.2 17 bp overlap

Motif DE_48h DE_48h-KLF13_MA0657.2 17 bp overlap

Motif DE_60h DE_60h-KLF13_MA0657.2 17 bp overlap

Motif DE_72h DE_72h-KLF13_MA0657.2 17 bp overlap

NR2F1 4 datasets

Motif DE_36h DE_36h-NR2F1_MA0017.3 12 bp overlap

Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap

Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap

Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap

Nfat5 4 datasets

Motif DE_36h DE_36h-Nfat5_MA0606.3 8 bp overlap

Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap

Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap

Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap

Nfatc2 4 datasets

Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap

Nr2F6 4 datasets

Motif DE_36h DE_36h-Nr2F6_MA0728.1 15 bp overlap

Motif DE_48h DE_48h-Nr2F6_MA0728.1 15 bp overlap

Motif DE_60h DE_60h-Nr2F6_MA0728.1 15 bp overlap

Motif DE_72h DE_72h-Nr2F6_MA0728.1 15 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 503 bp overlap

PRDM1 2 datasets

Motif DE_36h DE_36h-PRDM1_MA0508.4 7 bp overlap

Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap

RARA 4 datasets

Motif DE_36h DE_36h-RARA_MA0730.1 17 bp overlap

Motif DE_48h DE_48h-RARA_MA0730.1 17 bp overlap

Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap

Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap

Rarg 4 datasets

Motif DE_36h DE_36h-Rarg_MA0859.2 15 bp overlap

Motif DE_48h DE_48h-Rarg_MA0859.2 15 bp overlap

Motif DE_60h DE_60h-Rarg_MA0859.2 15 bp overlap

Motif DE_72h DE_72h-Rarg_MA0859.2 15 bp overlap

SCRT2 2 datasets

ChIP HEK293 ENCFF711QQB 275 bp overlap

ChIP HEK293 ENCFF711QQB 475 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 439 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 623 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 778 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 722 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 740 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 815 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 278 bp overlap

SOX10 1 dataset

Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 404 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 492 bp overlap

Motif DE_36h DE_36h-TBP_MA0108.3 7 bp overlap

Motif DE_48h DE_48h-TBP_MA0108.3 7 bp overlap

Motif DE_60h DE_60h-TBP_MA0108.3 7 bp overlap

Motif DE_72h DE_72h-TBP_MA0108.3 7 bp overlap

TRPS1 3 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

VEZF1 4 datasets

Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap

Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap

Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap

Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap

Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap

Motif DE_72h DE_72h-Yy1_MA0095.4 8 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF875HLX 294 bp overlap

ZBTB7B 1 dataset

Motif DE_36h DE_36h-ZBTB7B_MA0694.2 10 bp overlap

ZBTB7C 1 dataset

Motif DE_36h DE_36h-ZBTB7C_MA0695.2 8 bp overlap

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZFP42 5 datasets

Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap

Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap

Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap

Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap

Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap

ZNF16 2 datasets

Motif DE_36h DE_36h-ZNF16_MA1654.2 21 bp overlap

Motif DE_72h DE_72h-ZNF16_MA1654.2 21 bp overlap

ZNF316 2 datasets

ChIP K562 ENCFF281INV 376 bp overlap

ChIP K562 ENCFF281INV 457 bp overlap

ZNF341 1 dataset

Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap

ZNF667 4 datasets

Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap

Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap

ZNF768 2 datasets

Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap

Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap

ZNF8 4 datasets

Motif DE_36h DE_36h-ZNF8_MA1718.1 20 bp overlap

Motif DE_48h DE_48h-ZNF8_MA1718.1 20 bp overlap

Motif DE_60h DE_60h-ZNF8_MA1718.1 20 bp overlap

Motif DE_72h DE_72h-ZNF8_MA1718.1 20 bp overlap

ZSCAN16 1 dataset

Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap

Zfp335 2 datasets

Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap

Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap