chr16:67,262,177–67,262,869

chr16 : 67,262,177 – 67,262,869

692 bp 24 TFs 17 linked genes

This 692 bp open chromatin element is linked to 17 target genes and is bound by 24 transcription factors.

Linked Genes

17 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000262691		1.1 kb	Proximal	Proximity
FHOD1		15.0 kb	Distal	Multiome
SLC9A5		15.6 kb	Distal	Multiome
PLEKHG4		17.0 kb	Distal	Multiome
TMEM208		35.3 kb	Distal	Multiome
KCTD19		64.3 kb	Distal	Multiome
E2F4		70.3 kb	Distal	Multiome
MATCAP1		78.5 kb	Distal	Multiome
NOL3		91.9 kb	Distal	Multiome
ZDHHC1		133.8 kb	Distal	Multiome+HiCAR
PHAF1		152.5 kb	Distal	Multiome
HSD11B2		168.2 kb	Distal	Multiome
ATP6V0D1		218.7 kb	Distal	Multiome
ATP6V0D1-DT		218.8 kb	Distal	Multiome
CBFB		233.1 kb	Distal	Multiome
RIPOR1		266.3 kb	Distal	Multiome
CTCF		300.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

24 transcription factors

ARID2 2 datasets

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 249 bp overlap

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 281 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 312 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 184 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 102 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 57 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 459 bp overlap

ChIP DE DE-FOXA2-1 535 bp overlap

ChIP DE DE-FOXA2-2 470 bp overlap

GATA1 4 datasets

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 175 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 132 bp overlap

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 143 bp overlap

ChIP erythroid-progenitor_EPrec GSE124163.GATA1.erythroid-progenitor_EPrec 141 bp overlap

GATA2 1 dataset

ChIP SH-SY5Y ENCFF485YIB 405 bp overlap

GATA4 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 400 bp overlap

ChIP DE DE-GATA4-1 692 bp overlap

ChIP DE DE-GATA4-2 692 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 692 bp overlap

ChIP DE DE-GATA6-2 692 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 560 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 612 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 499 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 692 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 651 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 562 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 638 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 93 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 291 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 285 bp overlap

MYOD1 3 datasets

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 154 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 156 bp overlap

ChIP myoblast GSE50413.MYOD1.myoblast 136 bp overlap

POLR2A 1 dataset

ChIP HeLa-S3 ENCFF773DNG 388 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 534 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 532 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 477 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 444 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 520 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 323 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 692 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 692 bp overlap

SMAD3 2 datasets

ChIP endoderm GSE29422.SMAD3.endoderm 200 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 536 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 154 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 692 bp overlap

STAT5A 1 dataset

ChIP MV4-11 GSE64862.STAT5A.MV4-11 208 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 53 bp overlap