chr1 : 205,502,456 – 205,503,022
566 bp 45 TFs 4 linked genes
This 566 bp open chromatin element is linked to 4 target genes and is bound by 45 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CDK18 1.6 kb Proximal Proximity
ELK4 129.3 kb Distal Multiome
NUCKS1 247.5 kb Distal Multiome
DSTYK 291.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:205,497,456 – 205,508,022
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
45 transcription factors
Source
Cell type
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 294 bp overlap
E2F6 3 datasets
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 285 bp overlap
ESR2 2 datasets
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FEZF2 2 datasets
Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 286 bp overlap
ChIP DE DE-FOXA2-2 409 bp overlap
GATA1 4 datasets
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 55 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 152 bp overlap
GATA2 6 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 348 bp overlap
ChIP K562 ENCFF830LLA 492 bp overlap
ChIP K562 ENCFF830LLA 432 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 216 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 495 bp overlap
ChIP DE DE-GATA4-2 554 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 419 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 499 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 241 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP AGS GSE51705.GATA6.AGS 132 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 183 bp overlap
ChIP DE DE-GATA6-1 438 bp overlap
ChIP DE DE-GATA6-2 566 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 431 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 381 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 398 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 489 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 444 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 454 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 445 bp overlap
ChIP foregut GSE117136.GATA6.foregut 502 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 347 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 372 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 334 bp overlap
GFI1 3 datasets
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap
Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 113 bp overlap
Gata3 2 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Gli1 1 dataset
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
Gli2 1 dataset
Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap
HSF2 2 datasets
Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap
Motif DE_72h DE_72h-HSF2_MA0770.1 13 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 263 bp overlap
MEIS1 2 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
NKX2-2 2 datasets
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
NR2F1 1 dataset
Motif DE_72h DE_72h-NR2F1_MA1538.1 15 bp overlap
PHF21A 1 dataset
ChIP HepG2 ENCFF525EUW 61 bp overlap
PRDM9 3 datasets
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
RXRG 2 datasets
Motif DE_60h DE_60h-RXRG_MA1556.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA1556.1 14 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 493 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 377 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 250 bp overlap
SP4 3 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SREBF2 2 datasets
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap
SUZ12 3 datasets
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 541 bp overlap
ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 393 bp overlap
ChIP MCF-7 ENCSR757EMK.SUZ12.MCF-7 84 bp overlap
TRPS1 2 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZBTB6 1 dataset
ChIP HEK293 GSE76494.ZBTB6.HEK293 194 bp overlap
ZFX 2 datasets
ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 286 bp overlap
ChIP HepG2 ENCFF016NZF 566 bp overlap
ZKSCAN5 3 datasets
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF207 1 dataset
ChIP MCF-7 ENCSR096KWU.ZNF207.MCF-7 230 bp overlap
ZNF257 3 datasets
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF263 3 datasets
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap
ZNF3 1 dataset
ChIP HepG2 ENCFF299MFD 103 bp overlap
ZNF600 1 dataset
ChIP HEK293 ENCFF785JSX 185 bp overlap
ZNF93 2 datasets
Motif DE_48h DE_48h-ZNF93_MA1721.2 14 bp overlap
Motif DE_72h DE_72h-ZNF93_MA1721.2 14 bp overlap
ZSCAN21 2 datasets
Motif DE_48h DE_48h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap
Zic1::Zic2 3 datasets
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 3 datasets
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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