chr10 : 48,586,969 – 48,587,710
741 bp 50 TFs 1 linked gene
This 741 bp open chromatin element is linked to MAPK8 and is bound by 50 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MAPK8 280.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:48,581,969 – 48,592,710
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
50 transcription factors
Source
Cell type
AR 5 datasets
ChIP DU145 GSE47987.AR.DU145 87 bp overlap
ChIP DU145_ARQ6540X GSE47987.AR.DU145_ARQ6540X 157 bp overlap
ChIP PC-3_R1881 GSE54110.AR.PC-3_R1881 155 bp overlap
ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 152 bp overlap
ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 110 bp overlap
BCL6 1 dataset
ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 162 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 280 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 346 bp overlap
ChIP DE DE-FOXA2-2 328 bp overlap
FOXN3 2 datasets
Motif DE_36h DE_36h-FOXN3_MA1489.1 8 bp overlap
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
GATA2 2 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 683 bp overlap
ChIP DE DE-GATA4-2 726 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 713 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 496 bp overlap
ChIP DE DE-GATA6-2 658 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 741 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 738 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 669 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 741 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 741 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 741 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 741 bp overlap
ChIP foregut GSE117136.GATA6.foregut 741 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 740 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HSF1 2 datasets
ChIP MCF-7_hyperthermia-15min GSE137558.HSF1.MCF-7_hyperthermia-15min 125 bp overlap
ChIP MO91 GSE45852.HSF1.MO91 51 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Hnf1A 2 datasets
Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Lef1 2 datasets
Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
MED1 1 dataset
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 270 bp overlap
MEIS1 2 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MYC 1 dataset
ChIP OVCAR-3 GSE154941.MYC.OVCAR-3 168 bp overlap
MYF6 2 datasets
Motif DE_36h DE_36h-MYF6_MA0667.1 10 bp overlap
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
Mecom 2 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NCAPH2 1 dataset
ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 214 bp overlap
NR3C1 7 datasets
ChIP IMR-90 ERP007093.NR3C1.IMR-90 142 bp overlap
ChIP IMR-90_GLUCC ERP007081.NR3C1.IMR-90_GLUCC 142 bp overlap
ChIP MCF-7_E2_Dex GSE81510.NR3C1.MCF-7_E2_Dex 124 bp overlap
ChIP MCF-7_ICI_Dex GSE81510.NR3C1.MCF-7_ICI_Dex 169 bp overlap
ChIP MDA-MB-231 GSE152203.NR3C1.MDA-MB-231 178 bp overlap
ChIP SUM159PT GSE152203.NR3C1.SUM159PT 159 bp overlap
ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 190 bp overlap
PGR 2 datasets
ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 135 bp overlap
ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 108 bp overlap
PKNOX2 2 datasets
Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
PRDM9 2 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
SCRT1 1 dataset
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 164 bp overlap
SCRT2 1 dataset
ChIP HEK293 ENCFF711QQB 273 bp overlap
SMAD2 2 datasets
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 436 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 621 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 343 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 270 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 487 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 286 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 486 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 570 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 145 bp overlap
SOX11 1 dataset
ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 441 bp overlap
SP5 2 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SRSF7 1 dataset
ChIP Hep-G2 GSE120104.SRSF7.Hep-G2 239 bp overlap
SUPT16H 1 dataset
ChIP hiF-T GSE98758.SUPT16H.hiF-T 390 bp overlap
TCF7 2 datasets
Motif DE_36h DE_36h-TCF7_MA0769.3 7 bp overlap
Motif DE_60h DE_60h-TCF7_MA0769.3 7 bp overlap
TEAD1 2 datasets
ChIP H69 GSE62274.TEAD1.H69 75 bp overlap
ChIP H69 GSE62274.TEAD1.H69 151 bp overlap
TGIF1 2 datasets
Motif DE_36h DE_36h-TGIF1_MA0796.1 12 bp overlap
Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap
TGIF2 2 datasets
Motif DE_36h DE_36h-TGIF2_MA0797.1 12 bp overlap
Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap
TRIM25 1 dataset
ChIP MDA-MB-231 GSE79588.TRIM25.MDA-MB-231 314 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Thap11 2 datasets
Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap
Motif DE_60h DE_60h-Thap11_MA1573.2 14 bp overlap
ZBTB24 2 datasets
Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_60h DE_60h-ZBTB24_MA2330.1 10 bp overlap
ZFP14 2 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap
ZNF135 2 datasets
Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
ZNF257 2 datasets
Motif DE_36h DE_36h-ZNF257_MA1710.2 10 bp overlap
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
ZNF416 2 datasets
Motif DE_36h DE_36h-ZNF416_MA1979.2 10 bp overlap
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
ZNF460 2 datasets
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZSCAN16 2 datasets
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
Znf423 2 datasets
Motif DE_36h DE_36h-Znf423_MA0116.1 15 bp overlap
Motif DE_60h DE_60h-Znf423_MA0116.1 15 bp overlap
Huangfu Lab · Publications · Resources · Contact