chr7 : 108,521,893 – 108,522,657

764 bp 74 TFs 1 linked gene

This 764 bp open chromatin element is linked to PNPLA8 and is bound by 74 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PNPLA8		3.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

Arx 1 dataset

Motif DE_12h DE_12h-Arx_MA0874.2 10 bp overlap

BARX1 1 dataset

Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap

BRD4 1 dataset

ChIP HAP1 GSE108387.BRD4.HAP1 237 bp overlap

BSX 1 dataset

Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap

CDX1 1 dataset

Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap

CDX4 1 dataset

Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap

DLX1 1 dataset

Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_12h DE_12h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_12h DE_12h-Dlx5_MA1476.3 8 bp overlap

EN2 1 dataset

Motif DE_12h DE_12h-EN2_MA0642.3 7 bp overlap

ESR1_Y537N 2 datasets

ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 159 bp overlap

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 177 bp overlap

ESRRB 1 dataset

Motif DE_12h DE_12h-ESRRB_MA0141.4 10 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

GATA3 1 dataset

ChIP MCF-7 ENCFF352QVM 329 bp overlap

GBX1 1 dataset

Motif DE_12h DE_12h-GBX1_MA0889.2 7 bp overlap

GBX2 1 dataset

Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HESX1 1 dataset

Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap

HOXA10 1 dataset

Motif DE_12h DE_12h-HOXA10_MA0899.2 9 bp overlap

HOXA7 1 dataset

Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap

HOXB9 1 dataset

Motif DE_12h DE_12h-HOXB9_MA1503.2 9 bp overlap

HOXC10 1 dataset

Motif DE_12h DE_12h-HOXC10_MA0905.2 9 bp overlap

HOXC12 1 dataset

Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap

HOXC13 1 dataset

Motif DE_12h DE_12h-HOXC13_MA0907.2 9 bp overlap

HOXC9 1 dataset

Motif DE_12h DE_12h-HOXC9_MA0485.3 9 bp overlap

HOXD10 1 dataset

Motif DE_12h DE_12h-HOXD10_MA1506.2 10 bp overlap

HOXD11 1 dataset

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

HOXD12 1 dataset

Motif DE_12h DE_12h-HOXD12_MA0873.2 10 bp overlap

HOXD9 1 dataset

Motif DE_12h DE_12h-HOXD9_MA0913.3 9 bp overlap

Hoxa11 1 dataset

Motif DE_12h DE_12h-Hoxa11_MA0911.2 9 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

LBX1 1 dataset

Motif DE_12h DE_12h-LBX1_MA0618.2 7 bp overlap

LBX2 1 dataset

Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap

LHX9 1 dataset

Motif DE_12h DE_12h-LHX9_MA0701.3 7 bp overlap

Lhx1 1 dataset

Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap

MSX1 1 dataset

Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 406 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFIB 1 dataset

Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap

NFIC 1 dataset

Motif DE_12h DE_12h-NFIC_MA1527.2 15 bp overlap

NFIC::TLX1 1 dataset

Motif DE_12h DE_12h-NFICTLX1_MA0119.1 14 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Nobox 1 dataset

Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

PBX3 1 dataset

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 422 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 444 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 378 bp overlap

PRRX2 1 dataset

Motif DE_12h DE_12h-PRRX2_MA0075.4 7 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAX 1 dataset

Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 169 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 192 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 249 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

USF1 1 dataset

ChIP WA01 ENCSR000BIU.USF1.WA01 106 bp overlap

ZBTB6 1 dataset

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

ZMYM3 1 dataset

ChIP K562 ENCFF361LXT 292 bp overlap

ZNF136 1 dataset

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF652 1 dataset

Motif DE_12h DE_12h-ZNF652_MA1657.2 9 bp overlap

ZNF76 1 dataset

Motif DE_12h DE_12h-ZNF76_MA1716.2 17 bp overlap