chr5 : 40,916,304 – 40,916,691

387 bp 67 TFs 1 linked gene

This 387 bp open chromatin element is linked to C7 and is bound by 67 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
C7		6.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 177 bp overlap

CDX1 1 dataset

Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap

CDX4 1 dataset

Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 387 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 145 bp overlap

CTCF 2 datasets

ChIP K-562_WT GSE140868.CTCF.K-562_WT 96 bp overlap

ChIP endodermal cell ENCFF471YCZ 333 bp overlap

CTCFL 1 dataset

Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 222 bp overlap

ELL2 1 dataset

ChIP HeLa_DOX_EGF GSE40632.ELL2.HeLa_DOX_EGF 154 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 161 bp overlap

ERG 1 dataset

ChIP Jurkat GSE49091.ERG.Jurkat 124 bp overlap

FOXA1 1 dataset

Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 240 bp overlap

ChIP DE DE-FOXA2-2 220 bp overlap

FOXN3 2 datasets

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

Motif ES_0h ES_0h-FOXN3_MA1489.1 8 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 205 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 293 bp overlap

ChIP DE DE-GATA4-2 313 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 280 bp overlap

ChIP DE DE-GATA6-2 331 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 238 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 356 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 266 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 324 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 373 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 261 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 258 bp overlap

GLI3 1 dataset

Motif DE_12h DE_12h-GLI3_MA1491.3 15 bp overlap

Gli1 1 dataset

Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap

Gli2 1 dataset

Motif DE_12h DE_12h-Gli2_MA0734.4 9 bp overlap

HOXA10 1 dataset

Motif DE_12h DE_12h-HOXA10_MA0899.2 9 bp overlap

HOXB9 1 dataset

Motif DE_12h DE_12h-HOXB9_MA1503.2 9 bp overlap

HOXC10 1 dataset

Motif DE_12h DE_12h-HOXC10_MA0905.2 9 bp overlap

HOXC11 1 dataset

Motif DE_12h DE_12h-HOXC11_MA0651.3 11 bp overlap

HOXC12 1 dataset

Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap

HOXC13 1 dataset

Motif DE_12h DE_12h-HOXC13_MA0907.2 9 bp overlap

HOXC9 1 dataset

Motif DE_12h DE_12h-HOXC9_MA0485.3 9 bp overlap

HOXD10 1 dataset

Motif DE_12h DE_12h-HOXD10_MA1506.2 10 bp overlap

HOXD11 1 dataset

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

HOXD12 1 dataset

Motif DE_12h DE_12h-HOXD12_MA0873.2 10 bp overlap

HOXD9 1 dataset

Motif DE_12h DE_12h-HOXD9_MA0913.3 9 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

Hoxa11 1 dataset

Motif DE_12h DE_12h-Hoxa11_MA0911.2 9 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

INSM1 1 dataset

Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

NANOG 9 datasets

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 149 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 300 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 206 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 116 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 387 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 231 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 288 bp overlap

ChIP hESC GSE20650.NANOG.hESC 179 bp overlap

ChIP hESC GSE18292.NANOG.hESC 158 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1538.1 15 bp overlap

NR2F6 1 dataset

Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap

Nr2e3 1 dataset

Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap

POU5F1 3 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 282 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 308 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 146 bp overlap

Prdm15 1 dataset

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

RAD21 1 dataset

ChIP hiPSC_parental-line GSE106870.RAD21.hiPSC_parental-line 131 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

SIX1 1 dataset

Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 291 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 319 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 281 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 281 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 334 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 276 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 273 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 272 bp overlap

SMARCC1 3 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 245 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 184 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 240 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 151 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 283 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Six4 1 dataset

Motif DE_12h DE_12h-Six4_MA2001.2 7 bp overlap

Stat2 1 dataset

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 188 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0003.5 9 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap

ChIP HCC1954 GSE126897.TFAP2C.HCC1954 150 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 142 bp overlap

ZBTB7B 1 dataset

Motif DE_12h DE_12h-ZBTB7B_MA0694.2 10 bp overlap

ZBTB7C 1 dataset

Motif DE_12h DE_12h-ZBTB7C_MA0695.2 8 bp overlap

ZIM3 1 dataset

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

ZKSCAN1 1 dataset

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF136 2 datasets

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

Motif ES_0h ES_0h-ZNF136_MA1588.1 15 bp overlap

ZNF214 1 dataset

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF75D 1 dataset

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap