chr4 : 139,157,868 – 139,158,375
507 bp 74 TFs 1 linked gene
This 507 bp open chromatin element is linked to Metazoa_SRP and is bound by 74 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
Metazoa_SRP 2.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:139,152,868 – 139,163,375
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
74 transcription factors
Source
Cell type
ARNT::HIF1A 1 dataset
Motif DE_24h DE_24h-ARNTHIF1A_MA0259.2 5 bp overlap
ASCL1 3 datasets
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
Motif DE_24h DE_24h-ASCL1_MA1631.2 9 bp overlap
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
BCL6B 3 datasets
Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap
Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap
Motif DE_36h DE_36h-BCL6B_MA0731.1 17 bp overlap
CTCF 4 datasets
Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap
Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap
CUX1 2 datasets
Motif DE_12h DE_12h-CUX1_MA0754.3 9 bp overlap
Motif DE_24h DE_24h-CUX1_MA0754.3 9 bp overlap
CUX2 2 datasets
Motif DE_12h DE_12h-CUX2_MA0755.2 9 bp overlap
Motif DE_24h DE_24h-CUX2_MA0755.2 9 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF335XTP 55 bp overlap
ChIP BLaER1 ENCFF364PUR 254 bp overlap
DUX4 2 datasets
ChIP HEK293 GSE75791.DUX4.HEK293 93 bp overlap
ChIP WA01 GSE94322.DUX4.WA01 136 bp overlap
E2F6 2 datasets
Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap
Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap
E2F8 2 datasets
Motif DE_12h DE_12h-E2F8_MA0865.3 9 bp overlap
Motif DE_24h DE_24h-E2F8_MA0865.3 9 bp overlap
ETV6 1 dataset
ChIP WTC11 ENCFF812SCD 269 bp overlap
FIGLA 4 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
FOS 2 datasets
Motif DE_12h DE_12h-FOS_MA1951.2 13 bp overlap
Motif DE_24h DE_24h-FOS_MA1951.2 13 bp overlap
GATA4 1 dataset
ChIP DE DE-GATA4-2 340 bp overlap
GATA6 5 datasets
ChIP DE DE-GATA6-2 507 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 507 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 507 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 504 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 262 bp overlap
HIF1A 1 dataset
Motif DE_24h DE_24h-HIF1A_MA1106.2 6 bp overlap
HOXB13 3 datasets
Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap
Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap
Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap
Hmx1 2 datasets
Motif DE_12h DE_12h-Hmx1_MA0896.2 9 bp overlap
Motif DE_24h DE_24h-Hmx1_MA0896.2 9 bp overlap
Hmx2 2 datasets
Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap
Motif DE_24h DE_24h-Hmx2_MA0897.2 15 bp overlap
Hmx3 2 datasets
Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap
Motif DE_24h DE_24h-Hmx3_MA0898.2 9 bp overlap
Hoxa13 3 datasets
Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_36h DE_36h-Hoxa13_MA0650.4 8 bp overlap
Irf1 2 datasets
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
Motif DE_24h DE_24h-Irf1_MA0050.4 11 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 342 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 468 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 395 bp overlap
KLF1 2 datasets
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
KLF10 2 datasets
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
KLF14 2 datasets
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
KLF16 2 datasets
Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap
Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap
KLF2 2 datasets
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
KLF5 2 datasets
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
MAFK 1 dataset
Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap
MGA::EVX1 2 datasets
Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_24h DE_24h-MGAEVX1_MA1960.2 11 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 236 bp overlap
NFATC3 3 datasets
Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap
Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
NFATC4 3 datasets
Motif DE_12h DE_12h-NFATC4_MA1525.3 9 bp overlap
Motif DE_24h DE_24h-NFATC4_MA1525.3 9 bp overlap
Motif DE_36h DE_36h-NFATC4_MA1525.3 9 bp overlap
NR2C1 1 dataset
Motif DE_24h DE_24h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap
Motif DE_24h DE_24h-NR2C2_MA0504.2 14 bp overlap
Motif DE_24h DE_24h-NR2C2_MA1536.2 6 bp overlap
Nfat5 3 datasets
Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap
Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap
Motif DE_36h DE_36h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 3 datasets
Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 3 datasets
Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap
Nr1H2 1 dataset
Motif DE_24h DE_24h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_24h DE_24h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_24h DE_24h-Nr1h3_MA2337.1 6 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_24h DE_24h-Nr1h3Rxra_MA0494.2 16 bp overlap
PATZ1 2 datasets
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
PAX3 2 datasets
Motif DE_12h DE_12h-PAX3_MA0780.1 10 bp overlap
Motif DE_24h DE_24h-PAX3_MA0780.1 10 bp overlap
POLR2A 1 dataset
ChIP H1 ENCFF566JSR 498 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 306 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 303 bp overlap
PPARG 3 datasets
Motif DE_12h DE_12h-PPARG_MA0066.2 19 bp overlap
Motif DE_24h DE_24h-PPARG_MA0066.2 19 bp overlap
Motif DE_36h DE_36h-PPARG_MA0066.2 19 bp overlap
RARA 2 datasets
Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap
Motif DE_24h DE_24h-RARA_MA0729.1 18 bp overlap
RBPJ 2 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
SCRT1 3 datasets
Motif DE_12h DE_12h-SCRT1_MA0743.3 10 bp overlap
Motif DE_24h DE_24h-SCRT1_MA0743.3 10 bp overlap
Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 326 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 441 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 507 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 405 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 318 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 254 bp overlap
SPIB 2 datasets
Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap
Motif DE_24h DE_24h-SPIB_MA0081.3 13 bp overlap
TAF1 1 dataset
ChIP H1 ENCFF478SZO 448 bp overlap
TAF7 1 dataset
ChIP H1 ENCFF061XZZ 184 bp overlap
TBP 3 datasets
Motif DE_12h DE_12h-TBP_MA0108.3 7 bp overlap
Motif DE_24h DE_24h-TBP_MA0108.3 7 bp overlap
Motif DE_36h DE_36h-TBP_MA0108.3 7 bp overlap
TBX19 2 datasets
Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap
Motif DE_24h DE_24h-TBX19_MA0804.2 17 bp overlap
TCF4 3 datasets
Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap
Motif DE_24h DE_24h-TCF4_MA0830.3 8 bp overlap
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
Tbx6 2 datasets
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
VENTX 2 datasets
Motif DE_12h DE_12h-VENTX_MA0724.1 9 bp overlap
Motif DE_24h DE_24h-VENTX_MA0724.1 9 bp overlap
Wt1 3 datasets
Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap
Motif DE_24h DE_24h-Wt1_MA1627.2 10 bp overlap
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
Yy1 2 datasets
Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap
Motif DE_24h DE_24h-Yy1_MA0095.4 8 bp overlap
ZBTB17 2 datasets
Motif DE_12h DE_12h-ZBTB17_MA2102.1 8 bp overlap
Motif DE_24h DE_24h-ZBTB17_MA2102.1 8 bp overlap
ZBTB33 2 datasets
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 191 bp overlap
ChIP K562 ENCFF875HLX 188 bp overlap
ZEB1 4 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
ZIC4 3 datasets
Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap
Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap
Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap
ZIC5 3 datasets
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap
Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap
ZNF667 3 datasets
Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap
Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
ZNF768 1 dataset
Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap
ZNF784 3 datasets
Motif DE_12h DE_12h-ZNF784_MA1717.2 8 bp overlap
Motif DE_24h DE_24h-ZNF784_MA1717.2 8 bp overlap
Motif DE_36h DE_36h-ZNF784_MA1717.2 8 bp overlap
Huangfu Lab · Publications · Resources · Contact