chr4 : 134,936,097 – 134,936,344

247 bp 54 TFs 1 linked gene

This 247 bp open chromatin element is linked to ENSG00000249847 and is bound by 54 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000249847		2.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

54 transcription factors

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA0461.3 8 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 138 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 228 bp overlap

Crx 1 dataset

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

EP300 1 dataset

ChIP hESC GSE17917.EP300.hESC 199 bp overlap

GSC 1 dataset

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

Hand1 1 dataset

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 247 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 230 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000EBZ.JUND.WA01 162 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 2 datasets

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

MZF1 1 dataset

Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap

NANOG 7 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 247 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 195 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 139 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 247 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 247 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 247 bp overlap

ChIP hESC GSE18292.NANOG.hESC 202 bp overlap

NR3C1 1 dataset

ChIP Ishikawa ENCSR000BJC.NR3C1.Ishikawa 129 bp overlap

OTX1 1 dataset

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 6 datasets

ChIP GM23338 ENCFF333SNB 214 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 247 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 174 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 127 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 247 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 148 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm15 1 dataset

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

Rfx6 1 dataset

Motif DE_12h DE_12h-Rfx6_MA1724.2 9 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 246 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 177 bp overlap

SMARCA4 3 datasets

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 215 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 244 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 230 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 225 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 213 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 197 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 247 bp overlap

SREBF2 1 dataset

Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TCF7L2 1 dataset

ChIP MDA-MB-453 GSE45201.TCF7L2.MDA-MB-453 215 bp overlap

TP53 1 dataset

Motif DE_12h DE_12h-TP53_MA0106.3 18 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZBTB24 1 dataset

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

ZBTB7B 1 dataset

Motif DE_12h DE_12h-ZBTB7B_MA0694.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap