chr2 : 221,388,384 – 221,389,191
807 bp 51 TFs 1 linked gene
This 807 bp open chromatin element is linked to EPHA4 and is bound by 51 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EPHA4 183.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:221,383,384 – 221,394,191
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
51 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP NGP GSE134626.ARID1A.NGP 387 bp overlap
ASCL1 1 dataset
ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 276 bp overlap
BRD4 2 datasets
ChIP NCI-H2171 GSE101821.BRD4.NCI-H2171 175 bp overlap
ChIP NCI-H2171_DMSO GSE49224.BRD4.NCI-H2171_DMSO 403 bp overlap
CREB3L1 2 datasets
Motif DE_48h DE_48h-CREB3L1_MA0839.2 13 bp overlap
Motif DE_60h DE_60h-CREB3L1_MA0839.2 13 bp overlap
CTCF 1 dataset
ChIP endodermal cell ENCFF471YCZ 148 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 321 bp overlap
Elf5 3 datasets
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
FIGLA 1 dataset
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 266 bp overlap
ChIP DE DE-FOXA2-1 723 bp overlap
ChIP DE DE-FOXA2-2 690 bp overlap
GATA2 3 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 111 bp overlap
GATA4 8 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 360 bp overlap
ChIP DE DE-GATA4-1 734 bp overlap
ChIP DE DE-GATA4-2 764 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 450 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 380 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 289 bp overlap
GATA5 1 dataset
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP AGS GSE51705.GATA6.AGS 143 bp overlap
ChIP DE DE-GATA6-1 606 bp overlap
ChIP DE DE-GATA6-2 767 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 568 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 540 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 611 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 717 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 644 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 586 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 642 bp overlap
ChIP foregut GSE117136.GATA6.foregut 393 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 298 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 311 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 691 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 326 bp overlap
Gata3 2 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HAND2 1 dataset
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 269 bp overlap
IKZF2 4 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
IRF2 1 dataset
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
IRF4 1 dataset
Motif DE_48h DE_48h-IRF4_MA1419.2 14 bp overlap
IRF7 1 dataset
Motif DE_48h DE_48h-IRF7_MA0772.2 13 bp overlap
IRF9 1 dataset
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
MAX 2 datasets
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 364 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 294 bp overlap
MED1 1 dataset
ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 291 bp overlap
MEIS1 1 dataset
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MYC 2 datasets
ChIP NCI-H128 GSE41105.MYC.NCI-H128 200 bp overlap
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 307 bp overlap
Mecom 1 dataset
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
NCOR2 1 dataset
ChIP LS180_125 GSE39277.NCOR2.LS180_125 94 bp overlap
NEUROD1 3 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 276 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 325 bp overlap
ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 151 bp overlap
NFYA 1 dataset
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
NFYC 1 dataset
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
NKX2-1 1 dataset
ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 121 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 183 bp overlap
SCRT1 1 dataset
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
SCRT2 1 dataset
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 135 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 721 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 477 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 295 bp overlap
SMAD3 1 dataset
ChIP BG03 GSE21614.SMAD3.BG03 122 bp overlap
SMARCA4 2 datasets
ChIP NGP GSE134626.SMARCA4.NGP 146 bp overlap
ChIP NGP GSE134626.SMARCA4.NGP 284 bp overlap
SNAI2 1 dataset
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 319 bp overlap
STAT1::STAT2 1 dataset
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Stat2 1 dataset
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
TRPS1 2 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZEB1 1 dataset
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZIM3 1 dataset
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
ZNF362 1 dataset
ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 333 bp overlap
ZNF384 1 dataset
Motif DE_48h DE_48h-ZNF384_MA1125.2 8 bp overlap
ZNF766 1 dataset
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
ZNF792 1 dataset
ChIP HEK293T GSE78099.ZNF792.HEK293T 208 bp overlap
ZNF90 1 dataset
ChIP HEK293T GSE78099.ZNF90.HEK293T 294 bp overlap
Huangfu Lab · Publications · Resources · Contact