Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

41 transcription factors

ASCL1 4 datasets

Motif DE_60h DE_60h-ASCL1_MA1100.3 8 bp overlap

Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap

Motif DE_72h DE_72h-ASCL1_MA1100.3 8 bp overlap

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

BNC2 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR754GYI.BNC2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 240 bp overlap

BRD4 8 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 248 bp overlap

ChIP MDA-MB-231_JQ1 GSE116879.BRD4.MDA-MB-231_JQ1 73 bp overlap

ChIP MDA-MB-231_JQ1_MGSK2801 GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801 80 bp overlap

ChIP MDA-MB-231_JQ1_MGSK2801_rDNA GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801_rDNA 80 bp overlap

ChIP MDA-MB-231_JQ1_rDNA GSE116879.BRD4.MDA-MB-231_JQ1_rDNA 73 bp overlap

ChIP MDA-MB-231_MGSK2801 GSE116879.BRD4.MDA-MB-231_MGSK2801 75 bp overlap

ChIP MDA-MB-231_MGSK2801_rDNA GSE116879.BRD4.MDA-MB-231_MGSK2801_rDNA 75 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 73 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_neural-crest-cell GSE108506.CHD7.hiPSC_derived_neural-crest-cell 90 bp overlap

Dux 2 datasets

Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap

Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 196 bp overlap

ESRRG 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR023KKB.ESRRG.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 176 bp overlap

EZH2 1 dataset

ChIP THP-1 GSE135024.EZH2.THP-1 205 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 155 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 147 bp overlap

ChIP DE DE-FOXA2-2 245 bp overlap

GATA2 6 datasets

ChIP SH-SY5Y ENCFF485YIB 349 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 285 bp overlap

ChIP SK-N-SH ENCFF764OZD 318 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 178 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 281 bp overlap

ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 199 bp overlap

GATA3 7 datasets

ChIP BE2C GSE65664.GATA3.BE2C 165 bp overlap

ChIP Kelly GSE65664.GATA3.Kelly 181 bp overlap

ChIP MCF-7 ENCFF437NQS 247 bp overlap

ChIP MCF-7 GSE133072.GATA3.MCF-7 102 bp overlap

ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 127 bp overlap

ChIP SK-N-SH ENCFF040SSB 107 bp overlap

ChIP breast_tumor_Male_15 GSE104399.GATA3.breast_tumor_Male_15 254 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 297 bp overlap

ChIP DE DE-GATA4-2 418 bp overlap

ChIP foregut GSE117136.GATA4.foregut 291 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 182 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 264 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 279 bp overlap

ChIP DE DE-GATA6-2 437 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 272 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 367 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 424 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 343 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 309 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 311 bp overlap

ChIP foregut GSE117136.GATA6.foregut 302 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 205 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 235 bp overlap

HIC2 2 datasets

Motif DE_60h DE_60h-HIC2_MA0738.2 6 bp overlap

Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap

Hic1 2 datasets

Motif DE_60h DE_60h-Hic1_MA0739.2 8 bp overlap

Motif DE_72h DE_72h-Hic1_MA0739.2 8 bp overlap

ISL1 1 dataset

ChIP SK-N-SH ENCFF285GEQ 211 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 254 bp overlap

JUND 1 dataset

ChIP SK-N-SH ENCSR000BSK.JUND.SK-N-SH 59 bp overlap

MYOD1 2 datasets

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap

NKX2-1 1 dataset

ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 136 bp overlap

RELB 2 datasets

Motif DE_60h DE_60h-RELB_MA1117.2 7 bp overlap

Motif DE_72h DE_72h-RELB_MA1117.2 7 bp overlap

Rfx6 1 dataset

Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 347 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 318 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 373 bp overlap

SMARCA4 1 dataset

ChIP TTC-1240 GSE124903.SMARCA4.TTC-1240 110 bp overlap

SNAI1 2 datasets

Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap

Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap

SNAI2 2 datasets

Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap

Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap

SNAI3 2 datasets

Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap

Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap

TCF12 2 datasets

Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap

Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap

TCF3 2 datasets

Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap

Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap

TCF4 2 datasets

Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TFAP4 1 dataset

ChIP DLD-1 GSE46935.TFAP4.DLD-1 251 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZFP3 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 414 bp overlap

ZNF331 1 dataset

Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap

ZNF777 1 dataset

ChIP HEK293T GSE78099.ZNF777.HEK293T 253 bp overlap

ZSCAN4 1 dataset

Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap

Genome Browser