chr2 : 201,139,950 – 201,140,164

214 bp 47 TFs 2 linked genes

This 214 bp open chromatin element is linked to IMPDH1P10 and CFLAR and is bound by 47 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
IMPDH1P10		at TSS	At TSS	Proximity
CFLAR		8.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

47 transcription factors

ARNT::HIF1A 1 dataset

Motif ES_0h ES_0h-ARNTHIF1A_MA0259.2 5 bp overlap

ASCL1 2 datasets

Motif ES_0h ES_0h-ASCL1_MA1100.3 8 bp overlap

Motif ES_0h ES_0h-ASCL1_MA1631.2 9 bp overlap

Ascl2 1 dataset

Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap

BARHL1 1 dataset

Motif ES_0h ES_0h-BARHL1_MA0877.4 6 bp overlap

BARHL2 1 dataset

Motif ES_0h ES_0h-BARHL2_MA0635.2 6 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap

BHLHE22 1 dataset

Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap

CDK9 1 dataset

ChIP HCT-116 GSE72622.CDK9.HCT-116 100 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 141 bp overlap

EP300 1 dataset

ChIP MCF-7 GSE128445.EP300.MCF-7 153 bp overlap

ERF::NHLH1 1 dataset

Motif ES_0h ES_0h-ERFNHLH1_MA1938.2 16 bp overlap

ESR1 4 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 193 bp overlap

ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 214 bp overlap

ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 214 bp overlap

ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 123 bp overlap

FERD3L 1 dataset

Motif ES_0h ES_0h-FERD3L_MA1485.1 14 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 154 bp overlap

HMGB1 1 dataset

ChIP HUVEC-C GSE98245.HMGB1.HUVEC-C 130 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 120 bp overlap

KDM4A 2 datasets

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 214 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 175 bp overlap

MEN1 1 dataset

ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 214 bp overlap

MYOG 1 dataset

Motif ES_0h ES_0h-MYOG_MA0500.3 8 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 195 bp overlap

NHLH1 1 dataset

Motif ES_0h ES_0h-NHLH1_MA0048.3 9 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 214 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 214 bp overlap

Neurod2 1 dataset

Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap

POLR2A 2 datasets

ChIP GM12878 ENCFF521FXC 214 bp overlap

ChIP spleen ENCFF706IUS 214 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 214 bp overlap

ChIP K562 ENCFF648YPL 214 bp overlap

POU5F1 3 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 61 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 192 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 168 bp overlap

RAD21 1 dataset

ChIP hiPSC_parental-line GSE106870.RAD21.hiPSC_parental-line 127 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 187 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 187 bp overlap

RBM22 1 dataset

ChIP K-562 GSE120104.RBM22.K-562 169 bp overlap

REST 2 datasets

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 193 bp overlap

ChIP hiPSC_IID12 GSE106870.REST.hiPSC_IID12 211 bp overlap

RNF2 1 dataset

ChIP WA09 GSE105028.RNF2.WA09 172 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 208 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 214 bp overlap

SIN3A 1 dataset

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 143 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 188 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 214 bp overlap

STAT1 1 dataset

ChIP CD14_INFG_LPS GSE43036.STAT1.CD14_INFG_LPS 143 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 214 bp overlap

TCF7 1 dataset

ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 208 bp overlap

TP63 2 datasets

ChIP keratinocyte GSE33571.TP63.keratinocyte 68 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 90 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 194 bp overlap

Tcf12 1 dataset

Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap

WDR5 1 dataset

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 214 bp overlap

ZBTB33 2 datasets

Motif ES_0h ES_0h-ZBTB33_MA0527.2 10 bp overlap

ChIP K562 ENCFF427SDV 214 bp overlap

ZFP57 1 dataset

ChIP hESC GSE115387.ZFP57.hESC 214 bp overlap

ZNF460 1 dataset

Motif ES_0h ES_0h-ZNF460_MA1596.1 16 bp overlap

ZNF93 2 datasets

Motif ES_0h ES_0h-ZNF93_MA1721.2 14 bp overlap