chr18 : 51,573,769 – 51,574,737

968 bp 64 TFs 2 linked genes

This 968 bp open chromatin element is linked to LINC01630 and MEX3C and is bound by 64 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LINC01630		182.2 kb	Distal	Multiome
MEX3C		377.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

Atoh1 1 dataset

Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap

Bach1::Mafk 1 dataset

Motif DE_48h DE_48h-Bach1Mafk_MA0591.2 12 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 250 bp overlap

ELF4 1 dataset

ChIP K562 ENCFF200OMJ 230 bp overlap

EOMES 1 dataset

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

ETV2::FIGLA 2 datasets

Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap

Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap

EZH2 2 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 136 bp overlap

ChIP HeLa-S3 ENCFF318LHU 614 bp overlap

Elf5 1 dataset

Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap

FIGLA 1 dataset

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 955 bp overlap

ChIP DE DE-FOXA2-2 849 bp overlap

GABPA 1 dataset

Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 964 bp overlap

ChIP DE DE-GATA4-2 968 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 968 bp overlap

ChIP DE DE-GATA6-2 968 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 968 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 377 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 446 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 968 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 968 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 144 bp overlap

HAND2 1 dataset

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

Hand1 1 dataset

Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap

IKZF1 1 dataset

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

IRF3 2 datasets

Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap

Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap

IRF4 2 datasets

Motif DE_60h DE_60h-IRF4_MA1419.2 14 bp overlap

Motif DE_72h DE_72h-IRF4_MA1419.2 14 bp overlap

IRF8 2 datasets

Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap

Motif DE_72h DE_72h-IRF8_MA0652.2 13 bp overlap

IRF9 2 datasets

Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap

Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap

Irf1 2 datasets

Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap

Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap

JUN 2 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 346 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 300 bp overlap

MAFG::NFE2L1 1 dataset

Motif DE_48h DE_48h-MAFGNFE2L1_MA0089.3 11 bp overlap

MAFK 1 dataset

Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap

MGA 1 dataset

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

MSC 1 dataset

Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap

MYF6 1 dataset

Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

NEUROD1 1 dataset

Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap

Neurod2 1 dataset

Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 320 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

SCRT1 1 dataset

Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 454 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 359 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 524 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 671 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 634 bp overlap

SNAI2 1 dataset

Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 722 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 640 bp overlap

SP5 1 dataset

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

SPIB 1 dataset

Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap

Spi1 1 dataset

Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap

TFAP4::FLI1 2 datasets

Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap

Motif DE_72h DE_72h-TFAP4FLI1_MA1967.2 14 bp overlap

TWIST1 1 dataset

Motif DE_48h DE_48h-TWIST1_MA1123.3 8 bp overlap

Tbx6 1 dataset

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

Wt1 1 dataset

Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap

ZBTB12 2 datasets

Motif DE_60h DE_60h-ZBTB12_MA1649.2 7 bp overlap

Motif DE_72h DE_72h-ZBTB12_MA1649.2 7 bp overlap

ZBTB32 2 datasets

Motif DE_60h DE_60h-ZBTB32_MA1580.1 10 bp overlap

Motif DE_72h DE_72h-ZBTB32_MA1580.1 10 bp overlap

ZEB1 1 dataset

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZNF148 1 dataset

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

ZNF184 1 dataset

Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap

ZNF281 1 dataset

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

ZNF740 1 dataset

Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap