Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

BHLHE22 1 dataset

ChIP CAL-1 GSE43876.BHLHE22.CAL-1 507 bp overlap

BRD4 3 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 285 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 132 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD4.MV4-11_DMSO 133 bp overlap

CBX8 2 datasets

ChIP A-549 ENCSR616MOB.CBX8.A-549 788 bp overlap

ChIP A549 ENCFF656LMW 477 bp overlap

CLOCK 1 dataset

ChIP BA10_2 GSE96659.CLOCK.BA10_2 153 bp overlap

CTCF 1 dataset

ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 337 bp overlap

EHF 1 dataset

ChIP RWPE-1 GSE114241.EHF.RWPE-1 275 bp overlap

ESR1 2 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 206 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 120 bp overlap

EZH2 11 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 820 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 399 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 304 bp overlap

ChIP GM23248 ENCSR131FFJ.EZH2.GM23248 54 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 545 bp overlap

ChIP SK-N-MC ENCFF434OHW 506 bp overlap

ChIP SK-N-MC ENCFF434OHW 279 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 496 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 223 bp overlap

ChIP neural progenitor cell ENCFF472NFV 117 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 266 bp overlap

FOS 1 dataset

ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 214 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 296 bp overlap

FOXA2 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 279 bp overlap

GATA4 3 datasets

ChIP foregut GSE117136.GATA4.foregut 335 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 628 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 573 bp overlap

GATA6 7 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 276 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 526 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 348 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 452 bp overlap

ChIP foregut GSE117136.GATA6.foregut 342 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 516 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 454 bp overlap

HMGA2 1 dataset

ChIP WTC11 ENCFF535JLP 157 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IKZF3 2 datasets

ChIP HEK293 ENCFF518OXG 303 bp overlap

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 169 bp overlap

JUN 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 249 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 685 bp overlap

KDM5B 1 dataset

ChIP SUM185 GSE46055.KDM5B.SUM185 126 bp overlap

L3MBTL2 1 dataset

ChIP HEK293T ENCFF482NJV 60 bp overlap

MZF1 1 dataset

ChIP HEK293 ENCSR298QUH.MZF1.HEK293 233 bp overlap

NR1D1 1 dataset

Motif DE_12h DE_12h-NR1D1_MA1531.2 14 bp overlap

OSR2 1 dataset

Motif DE_12h DE_12h-OSR2_MA1646.2 8 bp overlap

PDX1 4 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 381 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 203 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 243 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 265 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 371 bp overlap

PRDM1 2 datasets

ChIP HEK293 ENCFF302TBP 369 bp overlap

ChIP HEK293 GSE76494.PRDM1.HEK293 152 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 445 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 439 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

RELA 2 datasets

ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 134 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 202 bp overlap

REPIN1 2 datasets

ChIP HEK293 ENCFF457XPY 54 bp overlap

ChIP HEK293 ENCSR146NLL.REPIN1.HEK293 170 bp overlap

RNF2 6 datasets

ChIP A-549 ENCSR798EGJ.RNF2.A-549 513 bp overlap

ChIP A549 ENCFF650XYA 343 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 206 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 247 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 455 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 246 bp overlap

SCRT1 1 dataset

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 247 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 521 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 192 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 314 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 420 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 170 bp overlap

SUZ12 3 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 282 bp overlap

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 231 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 254 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 207 bp overlap

TCF4 2 datasets

ChIP CAL-1 GSE76147.TCF4.CAL-1 704 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 441 bp overlap

TEAD1 1 dataset

ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 176 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 255 bp overlap

ZBTB42 1 dataset

ChIP HEK293 GSE76494.ZBTB42.HEK293 146 bp overlap

ZNF189 2 datasets

ChIP HEK293 ENCFF638TIB 277 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 395 bp overlap

ZNF24 1 dataset

ChIP HEK293 ENCFF308WOW 238 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 232 bp overlap

ZNF366 2 datasets

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 554 bp overlap

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 112 bp overlap

ZNF394 2 datasets

ChIP HEK293 ENCFF236OPX 417 bp overlap

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 332 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 461 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 257 bp overlap

Genome Browser