chr13 : 60,167,221 – 60,167,961

740 bp 51 TFs 1 linked gene

This 740 bp open chromatin element is linked to DIAPH3 and is bound by 51 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
DIAPH3		3.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

51 transcription factors

BRD4 1 dataset

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 242 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 295 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 424 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 426 bp overlap

ChIP DE DE-FOXA2-2 480 bp overlap

FOXC2 1 dataset

Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap

FOXD2 1 dataset

Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap

FOXF2 1 dataset

Motif DE_60h DE_60h-FOXF2_MA0030.2 9 bp overlap

FOXK1 1 dataset

Motif DE_60h DE_60h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_60h DE_60h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_60h DE_60h-FOXL1_MA0033.2 7 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO4 1 dataset

Motif DE_60h DE_60h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_60h DE_60h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_60h DE_60h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_60h DE_60h-Foxf1_MA1606.2 7 bp overlap

Foxl2 1 dataset

Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_60h DE_60h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_60h DE_60h-Foxo3_MA0157.4 7 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 229 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 590 bp overlap

ChIP DE DE-GATA4-2 616 bp overlap

ChIP foregut GSE117136.GATA4.foregut 483 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 241 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 502 bp overlap

ChIP DE DE-GATA6-2 740 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 546 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 482 bp overlap

ChIP foregut GSE117136.GATA6.foregut 418 bp overlap

HAND2 1 dataset

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

Hand1 1 dataset

Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

KLF17 1 dataset

Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap

MEIS1 2 datasets

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Mecom 1 dataset

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

NKX2-4 1 dataset

Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap

NKX2-8 1 dataset

Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap

NR6A1 1 dataset

Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap

PDX1 1 dataset

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 286 bp overlap

PGR 7 datasets

ChIP T-47D-B_R5020 GSE80358.PGR.T-47D-B_R5020 218 bp overlap

ChIP T-47D_E2PG GSE68356.PGR.T-47D_E2PG 202 bp overlap

ChIP T-47D_PG GSE68356.PGR.T-47D_PG 246 bp overlap

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 309 bp overlap

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 300 bp overlap

ChIP T-47D_R5020-A1 GSE126859.PGR.T-47D_R5020-A1 337 bp overlap

ChIP T-47D_R5020-MTVL GSE126859.PGR.T-47D_R5020-MTVL 274 bp overlap

SCRT1 1 dataset

Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap

SMAD2 1 dataset

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 510 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 127 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 423 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 485 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 180 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 482 bp overlap

SP5 1 dataset

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

TEAD4 1 dataset

ChIP MKN28 GSE44416.TEAD4.MKN28 171 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 193 bp overlap

TP63 1 dataset

ChIP breast-organoid GSE113909.TP63.breast-organoid 130 bp overlap

TWIST1 1 dataset

Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap

ZFP14 1 dataset

Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap

ZNF140 1 dataset

Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap

ZNF341 1 dataset

Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap

ZNF460 1 dataset

Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap

ZNF558 1 dataset

Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap

ZNF667 2 datasets

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 241 bp overlap