chr12 : 129,163,411 – 129,164,328

917 bp 64 TFs 1 linked gene

This 917 bp open chromatin element is linked to TMEM132D and is bound by 64 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TMEM132D		740.2 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

BAP1 1 dataset

ChIP NCI-H1963_shASXL3 GSE145028.BAP1.NCI-H1963_shASXL3 533 bp overlap

BARX2 1 dataset

Motif DE_36h DE_36h-BARX2_MA1471.2 9 bp overlap

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 209 bp overlap

BRD4 2 datasets

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 167 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 668 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 257 bp overlap

CHD8 1 dataset

ChIP T-47D GSE62428.CHD8.T-47D 195 bp overlap

CTCF 1 dataset

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 229 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 540 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 520 bp overlap

ERF::HOXB13 1 dataset

Motif DE_36h DE_36h-ERFHOXB13_MA1937.2 13 bp overlap

ESR1 1 dataset

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 134 bp overlap

ETV2::DRGX 1 dataset

Motif DE_36h DE_36h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap

EZH2 4 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 87 bp overlap

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 459 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 297 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 367 bp overlap

FLI1::DRGX 1 dataset

Motif DE_36h DE_36h-FLI1DRGX_MA1949.2 14 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 716 bp overlap

ChIP DE DE-FOXA2-2 710 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 622 bp overlap

ChIP DE DE-GATA4-2 770 bp overlap

ChIP foregut GSE117136.GATA4.foregut 402 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 763 bp overlap

ChIP DE DE-GATA6-2 901 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 294 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 581 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 658 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 640 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 436 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 730 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_36h DE_36h-HOXB2ELK1_MA1957.1 14 bp overlap

HOXD12::ELK1 1 dataset

Motif DE_36h DE_36h-HOXD12ELK1_MA1958.2 13 bp overlap

Isl1 1 dataset

Motif DE_36h DE_36h-Isl1_MA1608.2 7 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 311 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 303 bp overlap

MGA::EVX1 1 dataset

Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap

NANOG 4 datasets

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 135 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 724 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 690 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 210 bp overlap

NKX6-3 1 dataset

Motif DE_36h DE_36h-NKX6-3_MA1530.2 8 bp overlap

PHF19 1 dataset

ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 223 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 237 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 313 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 275 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 915 bp overlap

PRPF4 2 datasets

ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 169 bp overlap

ChIP Hep-G2 GSE120104.PRPF4.Hep-G2 169 bp overlap

RBPJ 1 dataset

Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 187 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 617 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 493 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 641 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 526 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 231 bp overlap

SOX13 1 dataset

Motif DE_36h DE_36h-SOX13_MA1120.2 7 bp overlap

SOX14 1 dataset

Motif DE_36h DE_36h-SOX14_MA1562.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 702 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 766 bp overlap

SOX2 1 dataset

Motif DE_36h DE_36h-SOX2_MA0143.5 7 bp overlap

SOX4 1 dataset

Motif DE_36h DE_36h-SOX4_MA0867.3 8 bp overlap

SOX8 1 dataset

Motif DE_36h DE_36h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_36h DE_36h-SOX9_MA0077.2 8 bp overlap

SRY 1 dataset

Motif DE_36h DE_36h-SRY_MA0084.2 7 bp overlap

Sox17 1 dataset

Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap

Sox3 1 dataset

Motif DE_36h DE_36h-Sox3_MA0514.3 7 bp overlap

Sox5 1 dataset

Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 627 bp overlap

TBP 1 dataset

ChIP K-562 GSE55306.TBP.K-562 158 bp overlap

TBR1 1 dataset

Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap

TBX2 1 dataset

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX3 1 dataset

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 330 bp overlap

TFAP2A 1 dataset

Motif DE_36h DE_36h-TFAP2A_MA0810.2 11 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 277 bp overlap

Tbx6 1 dataset

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

VENTX 1 dataset

Motif DE_36h DE_36h-VENTX_MA0724.1 9 bp overlap

YY1 1 dataset

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 197 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 118 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 501 bp overlap

ZNF454 1 dataset

Motif DE_36h DE_36h-ZNF454_MA1712.2 17 bp overlap

ZNF528 2 datasets

Motif DE_36h DE_36h-ZNF528_MA1597.1 17 bp overlap

ChIP HEK293 GSE76494.ZNF528.HEK293 267 bp overlap

Znf423 1 dataset

Motif DE_36h DE_36h-Znf423_MA0116.1 15 bp overlap