chr12 : 42,459,344 – 42,460,044
700 bp 40 TFs 1 linked gene
This 700 bp open chromatin element is linked to ENSG00000257225 and is bound by 40 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000257225 at TSS At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:42,454,344 – 42,465,044
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
40 transcription factors
Source
Cell type
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 112 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 395 bp overlap
BCL6 1 dataset
ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 244 bp overlap
BCOR 2 datasets
ChIP WA01 GSE104690.BCOR.WA01 236 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 300 bp overlap
CLOCK 1 dataset
ChIP U2OS GSE44236.CLOCK.U2OS 169 bp overlap
CTCF 1 dataset
ChIP GSC23 GSE139416.CTCF.GSC23 227 bp overlap
CTNNB1 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 293 bp overlap
EP300 1 dataset
ChIP MCF-7 GSE128445.EP300.MCF-7 126 bp overlap
ESR1 98 datasets
ChIP MCF-7 ENCFF004AKH 217 bp overlap
ChIP MCF-7 GSE148277.ESR1.MCF-7 541 bp overlap
ChIP MCF-7 GSE117492.ESR1.MCF-7 234 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 270 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 325 bp overlap
ChIP MCF-7 GSE128445.ESR1.MCF-7 142 bp overlap
ChIP MCF-7 GSE136302.ESR1.MCF-7 180 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 306 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 178 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 112 bp overlap
ChIP MCF-7 GSE95302.ESR1.MCF-7 143 bp overlap
ChIP MCF-7-Luc_E2 GSE78284.ESR1.MCF-7-Luc_E2 138 bp overlap
ChIP MCF-7_1-6-HD GSE117492.ESR1.MCF-7_1-6-HD 198 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT_clone14 190 bp overlap
ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 128 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 132 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 394 bp overlap
ChIP MCF-7_DMSO GSE148277.ESR1.MCF-7_DMSO 187 bp overlap
ChIP MCF-7_E2 GSE81510.ESR1.MCF-7_E2 128 bp overlap
ChIP MCF-7_E2 GSE60270.ESR1.MCF-7_E2 321 bp overlap
ChIP MCF-7_E2 GSE59530.ESR1.MCF-7_E2 113 bp overlap
ChIP MCF-7_E2 GSE115607.ESR1.MCF-7_E2 113 bp overlap
ChIP MCF-7_E2 GSE71276.ESR1.MCF-7_E2 245 bp overlap
ChIP MCF-7_E2 GSE73956.ESR1.MCF-7_E2 249 bp overlap
ChIP MCF-7_E2 GSE72249.ESR1.MCF-7_E2 199 bp overlap
ChIP MCF-7_E2 GSE68356.ESR1.MCF-7_E2 281 bp overlap
ChIP MCF-7_E2 GSE86538.ESR1.MCF-7_E2 163 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 189 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 227 bp overlap
ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 192 bp overlap
ChIP MCF-7_E2 ERP000380.ESR1.MCF-7_E2 132 bp overlap
ChIP MCF-7_E2+4OHT GSE119702.ESR1.MCF-7_E2+4OHT 143 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 191 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 195 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 279 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 169 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 157 bp overlap
ChIP MCF-7_E2PG GSE68356.ESR1.MCF-7_E2PG 208 bp overlap
ChIP MCF-7_E2_30min GSE108883.ESR1.MCF-7_E2_30min 167 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 266 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 172 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 218 bp overlap
ChIP MCF-7_E2_Dex GSE81510.ESR1.MCF-7_E2_Dex 244 bp overlap
ChIP MCF-7_E2_TNF GSE59530.ESR1.MCF-7_E2_TNF 171 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 63 bp overlap
ChIP MCF-7_Fulv GSE115607.ESR1.MCF-7_Fulv 219 bp overlap
ChIP MCF-7_GLYC ERP002305.ESR1.MCF-7_GLYC 137 bp overlap
ChIP MCF-7_HC11 GSE102882.ESR1.MCF-7_HC11 180 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 152 bp overlap
ChIP MCF-7_IL1b-ICI GSE67295.ESR1.MCF-7_IL1b-ICI 169 bp overlap
ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 160 bp overlap
ChIP MCF-7_LTED_E2 GSE86538.ESR1.MCF-7_LTED_E2 206 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 348 bp overlap
ChIP MCF-7_OHT GSE119702.ESR1.MCF-7_OHT 143 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 155 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 133 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 173 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 261 bp overlap
ChIP MCF-7_SHCTR_E2 GSE60270.ESR1.MCF-7_SHCTR_E2 302 bp overlap
ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 337 bp overlap
ChIP MCF-7_SHFOXA1_E2_TNF GSE59530.ESR1.MCF-7_SHFOXA1_E2_TNF 67 bp overlap
ChIP MCF-7_SHGATA3_E2 GSE60270.ESR1.MCF-7_SHGATA3_E2 271 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 136 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 116 bp overlap
ChIP MCF-7_Sat-H3B-6545 GSE115607.ESR1.MCF-7_Sat-H3B-6545 121 bp overlap
ChIP MCF-7_TAMR GSE86538.ESR1.MCF-7_TAMR 128 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 210 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 167 bp overlap
ChIP MCF-7_WT GSE136302.ESR1.MCF-7_WT 132 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 214 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 231 bp overlap
ChIP MCF-7_estradiol-Dex_75min GSE99626.ESR1.MCF-7_estradiol-Dex_75min 74 bp overlap
ChIP MCF-7_estradiol-R5020_45min GSE99626.ESR1.MCF-7_estradiol-R5020_45min 170 bp overlap
ChIP MCF-7_estradiol-aldosterone_4h GSE99626.ESR1.MCF-7_estradiol-aldosterone_4h 166 bp overlap
ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 232 bp overlap
ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 184 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 234 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 243 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 236 bp overlap
ChIP MCF-7_jc5853 GSE126004.ESR1.MCF-7_jc5853 159 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 261 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 307 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 88 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 154 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 332 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 357 bp overlap
ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 261 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 283 bp overlap
ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 145 bp overlap
ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 237 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 284 bp overlap
ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 320 bp overlap
ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 325 bp overlap
ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 396 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 141 bp overlap
ChIP VCaP_E2_ERA GSE43985.ESR1.VCaP_E2_ERA 306 bp overlap
ChIP ZR751_E2 GSE72249.ESR1.ZR751_E2 144 bp overlap
ChIP breast_tumor_Male_5 GSE104399.ESR1.breast_tumor_Male_5 156 bp overlap
ESR1_D538G 1 dataset
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 322 bp overlap
ESR1_Y537C 1 dataset
ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 420 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 292 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 284 bp overlap
ESR1_Y537S 4 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 160 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 245 bp overlap
ChIP T-47D_dox GSE94493.ESR1_Y537S.T-47D_dox 219 bp overlap
ChIP T-47D_dox_E2 GSE94493.ESR1_Y537S.T-47D_dox_E2 207 bp overlap
ESR1_pS118 2 datasets
ChIP MCF-7_E2_ab GSE117569.ESR1_pS118.MCF-7_E2_ab 247 bp overlap
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 267 bp overlap
EZH2 1 dataset
ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 77 bp overlap
FOXA1 9 datasets
ChIP 22Rv1 GSE96652.FOXA1.22Rv1 206 bp overlap
ChIP MCF-7 ERP001226.FOXA1.MCF-7 103 bp overlap
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 419 bp overlap
ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 63 bp overlap
ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 152 bp overlap
ChIP MCF-7_ETOH GSE23852.FOXA1.MCF-7_ETOH 161 bp overlap
ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 199 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 230 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 263 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 423 bp overlap
ChIP DE DE-FOXA2-2 341 bp overlap
NANOG 10 datasets
ChIP GM23338 ENCFF065NZG 170 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 328 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 476 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 488 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 153 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 700 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 700 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 503 bp overlap
ChIP hESC GSE20650.NANOG.hESC 283 bp overlap
ChIP hESC GSE18292.NANOG.hESC 174 bp overlap
NCOA2 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 106 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 115 bp overlap
NIPBL 4 datasets
ChIP hESC GSE64758.NIPBL.hESC 221 bp overlap
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 233 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 299 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 340 bp overlap
NR3C1 2 datasets
ChIP A-549 ENCSR000BJR.NR3C1.A-549 185 bp overlap
ChIP A-549 ENCSR000BHF.NR3C1.A-549 129 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 131 bp overlap
PGR 1 dataset
ChIP T-47D_PG GSE68356.PGR.T-47D_PG 166 bp overlap
POU5F1 9 datasets
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 383 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 297 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 633 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 248 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 211 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 596 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 553 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 305 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 213 bp overlap
RNF2 1 dataset
ChIP WA09 GSE105028.RNF2.WA09 394 bp overlap
SMAD2 3 datasets
ChIP hESC GSE29422.SMAD2.hESC 119 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 664 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 295 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 524 bp overlap
SMAD3 2 datasets
ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap
ChIP hESC GSE29422.SMAD3.hESC 184 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 214 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 191 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 234 bp overlap
SOX2 2 datasets
ChIP hESC GSE18292.SOX2.hESC 102 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 333 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 161 bp overlap
TEAD4 1 dataset
ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 205 bp overlap
TFAP2C 2 datasets
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 180 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 279 bp overlap
YY1AP1 1 dataset
ChIP MCF-7_E2 GSE125594.YY1AP1.MCF-7_E2 140 bp overlap
ZNF143 2 datasets
ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 271 bp overlap
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 274 bp overlap
ZNF528 1 dataset
ChIP HEK293 GSE76494.ZNF528.HEK293 59 bp overlap
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