Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

ASCL1 2 datasets

Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

CDX2 4 datasets

ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 226 bp overlap

ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 248 bp overlap

ChIP LS180_125 GSE31939.CDX2.LS180_125 117 bp overlap

ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 218 bp overlap

CTCF 1 dataset

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 461 bp overlap

EOMES 2 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 186 bp overlap

EP300 1 dataset

ChIP upper lobe of left lung ENCFF024QBJ 202 bp overlap

ESR1_pS118 3 datasets

ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 81 bp overlap

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 149 bp overlap

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 148 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 352 bp overlap

ChIP DE DE-GATA4-2 464 bp overlap

ChIP foregut GSE117136.GATA4.foregut 357 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 442 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 250 bp overlap

GATA5 2 datasets

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 360 bp overlap

ChIP DE DE-GATA6-2 503 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 287 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 291 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 308 bp overlap

ChIP foregut GSE117136.GATA6.foregut 335 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 287 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 346 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 274 bp overlap

GFI1 2 datasets

Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

Gata3 2 datasets

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 425 bp overlap

HNF4A 2 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 214 bp overlap

ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 139 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 505 bp overlap

MYOD1 2 datasets

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap

NANOG 2 datasets

ChIP WA01 ENCSR000BMT.NANOG.WA01 181 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 316 bp overlap

Nr5A2 2 datasets

Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap

Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap

PDX1 1 dataset

ChIP hiPSC GSE125768.PDX1.hiPSC 254 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 508 bp overlap

Rfx6 2 datasets

Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap

Motif DE_72h DE_72h-Rfx6_MA1724.2 9 bp overlap

SMAD2 2 datasets

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 368 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 174 bp overlap

SMARCA4 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 342 bp overlap

SMARCC1 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-T910M 321 bp overlap

SP4 1 dataset

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

SS18 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SS18.BIN-67_lentivirus-SMARCA4-T910M 215 bp overlap

STAT1 2 datasets

Motif DE_60h DE_60h-STAT1_MA0137.4 9 bp overlap

Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap

STAT3 2 datasets

Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap

Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 105 bp overlap

Stat5a 1 dataset

Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX20 1 dataset

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TCF4 2 datasets

Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TEAD1 3 datasets

Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 151 bp overlap

TEAD2 2 datasets

Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD3 2 datasets

Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 207 bp overlap

TRPS1 2 datasets

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Tbx6 1 dataset

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZIM3 1 dataset

Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap

ZNF263 1 dataset

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap

Genome Browser