chr5 : 126,317,233 – 126,317,918
685 bp 47 TFs 4 linked genes
This 685 bp open chromatin element is linked to 4 target genes and is bound by 47 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000248752 51.2 kb Distal Multiome
GRAMD2B 105.8 kb Distal Multiome
ALDH7A1 277.6 kb Distal Multiome
PHAX 283.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:126,312,233 – 126,322,918
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
47 transcription factors
Source
Cell type
Ahr::Arnt 3 datasets
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BARX2 2 datasets
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap
BCL6B 2 datasets
Motif DE_60h DE_60h-BCL6B_MA0731.1 17 bp overlap
Motif DE_72h DE_72h-BCL6B_MA0731.1 17 bp overlap
CRX 2 datasets
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 211 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 353 bp overlap
Dmrt1 1 dataset
Motif DE_72h DE_72h-Dmrt1_MA1603.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 420 bp overlap
ERF::FOXO1 2 datasets
Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 217 bp overlap
ChIP DE DE-FOXA2-1 663 bp overlap
ChIP DE DE-FOXA2-2 632 bp overlap
GABPA 1 dataset
ChIP VCaP_R1881 GSE49091.GABPA.VCaP_R1881 142 bp overlap
GATA1::TAL1 3 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 2 datasets
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 8 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 205 bp overlap
ChIP DE DE-GATA4-1 685 bp overlap
ChIP DE DE-GATA4-2 676 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 214 bp overlap
ChIP foregut GSE117136.GATA4.foregut 440 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 319 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 665 bp overlap
ChIP DE DE-GATA6-2 685 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 434 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 429 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 613 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 445 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 460 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 604 bp overlap
ChIP foregut GSE117136.GATA6.foregut 290 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 400 bp overlap
Gata3 4 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Gfi1B 3 datasets
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MYBL1 2 datasets
Motif DE_48h DE_48h-MYBL1_MA0776.1 12 bp overlap
Motif DE_60h DE_60h-MYBL1_MA0776.1 12 bp overlap
MYBL2 2 datasets
Motif DE_48h DE_48h-MYBL2_MA0777.1 15 bp overlap
Motif DE_60h DE_60h-MYBL2_MA0777.1 15 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 247 bp overlap
OVOL1 2 datasets
Motif DE_48h DE_48h-OVOL1_MA1544.2 10 bp overlap
Motif DE_60h DE_60h-OVOL1_MA1544.2 10 bp overlap
OVOL2 2 datasets
Motif DE_48h DE_48h-OVOL2_MA1545.2 7 bp overlap
Motif DE_60h DE_60h-OVOL2_MA1545.2 7 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
RBPJ 2 datasets
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RXRA::VDR 2 datasets
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 643 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 258 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 599 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 529 bp overlap
SMAD3 2 datasets
Motif DE_60h DE_60h-SMAD3_MA0795.1 10 bp overlap
Motif DE_72h DE_72h-SMAD3_MA0795.1 10 bp overlap
SMAD5 2 datasets
Motif DE_60h DE_60h-SMAD5_MA1557.1 10 bp overlap
Motif DE_72h DE_72h-SMAD5_MA1557.1 10 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 333 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 499 bp overlap
SOX4 2 datasets
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
STAT1::STAT2 2 datasets
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
STAT3 2 datasets
Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
Smad4 2 datasets
Motif DE_60h DE_60h-Smad4_MA1153.2 7 bp overlap
Motif DE_72h DE_72h-Smad4_MA1153.2 7 bp overlap
Sox11 2 datasets
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Stat2 2 datasets
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 264 bp overlap
TCF7L2 2 datasets
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 4 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZIM3 3 datasets
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap
ZNF416 2 datasets
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap
ZNF582 3 datasets
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap
Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap
ZNF677 2 datasets
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF85 3 datasets
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap
Zfp809 2 datasets
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
Huangfu Lab · Publications · Resources · Contact