chr5 : 107,705,106 – 107,705,336

230 bp 58 TFs 1 linked gene

This 230 bp open chromatin element is linked to ENSG00000249959 and is bound by 58 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000249959		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

ASXL3 2 datasets

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 153 bp overlap

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 96 bp overlap

ATRX 1 dataset

ChIP metastatic-neuroblastoma_SKNFI GSE100148.ATRX.metastatic-neuroblastoma_SKNFI 230 bp overlap

BAP1 1 dataset

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 230 bp overlap

BRD4 7 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 128 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 117 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 230 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 93 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 230 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 230 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 88 bp overlap

Bach1::Mafk 1 dataset

Motif DE_12h DE_12h-Bach1Mafk_MA0591.2 12 bp overlap

CTCF 1 dataset

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 136 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap

ERG 1 dataset

ChIP aortic-endothelial-cell_D49 GSE139377.ERG.aortic-endothelial-cell_D49 126 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

GFI1 1 dataset

Motif DE_12h DE_12h-GFI1_MA0038.3 11 bp overlap

HAND2 2 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 230 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 230 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IRF3 1 dataset

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 230 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

KLF4 1 dataset

ChIP HAP1 GSE130417.KLF4.HAP1 95 bp overlap

MAF::NFE2 1 dataset

Motif DE_12h DE_12h-MAFNFE2_MA0501.2 11 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 230 bp overlap

MAFK 1 dataset

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

MYCN 1 dataset

ChIP CHP-134 GSE129588.MYCN.CHP-134 164 bp overlap

Mafg 1 dataset

Motif DE_12h DE_12h-Mafg_MA0659.4 12 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 175 bp overlap

Nfatc2 1 dataset

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Nfe2l2 1 dataset

Motif DE_12h DE_12h-Nfe2l2_MA0150.3 11 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 230 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 230 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 230 bp overlap

RAD21 2 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 221 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 76 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 137 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 230 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 230 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 230 bp overlap

SMARCA2 1 dataset

ChIP NPC_K755R-pos GSE122631.SMARCA2.NPC_K755R-pos 211 bp overlap

SMARCA4 3 datasets

ChIP Aska-SS_shSSX GSE108025.SMARCA4.Aska-SS_shSSX 108 bp overlap

ChIP NGP GSE134626.SMARCA4.NGP 114 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 60 bp overlap

SMARCC1 1 dataset

ChIP Aska-SS_shSSX GSE108025.SMARCC1.Aska-SS_shSSX 230 bp overlap

SOX8 1 dataset

ChIP RH4_DMSO-6H GSE116344.SOX8.RH4_DMSO-6H 120 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

SPIC 1 dataset

Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

Stat2 1 dataset

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

TBX2 1 dataset

ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 230 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

TEAD4 2 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 72 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 72 bp overlap

ZEB1 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 112 bp overlap

ZIM3 1 dataset

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

ZNF24 1 dataset

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

ZNF317 1 dataset

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF549 1 dataset

Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap

ZNF558 1 dataset

Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap

ZNF669 1 dataset

Motif DE_12h DE_12h-ZNF669_MA1985.1 15 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

Zfp335 1 dataset

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap