Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

ARID2 1 dataset

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 341 bp overlap

BRD4 1 dataset

ChIP HEK293_sgMYOD GSE129407.BRD4.HEK293_sgMYOD 226 bp overlap

CTCF 14 datasets

ChIP A-549 ENCSR000DPF.CTCF.A-549 140 bp overlap

Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap

ChIP GM04648 GSE148179.CTCF.GM04648 228 bp overlap

ChIP GM12864 ENCFF357DQE 285 bp overlap

ChIP HEC-1-B_WT GSE140868.CTCF.HEC-1-B_WT 304 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 320 bp overlap

ChIP MCF-7 ENCSR000DWH.CTCF.MCF-7 146 bp overlap

ChIP colon_transverse ENCSR833FWC.CTCF.colon_transverse 273 bp overlap

ChIP endodermal cell ENCFF471YCZ 131 bp overlap

ChIP endodermal cell ENCFF471YCZ 461 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 117 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DVP.CTCF.endothelial_umbilical-vein 117 bp overlap

ChIP epithelial cell of esophagus ENCFF946GGT 305 bp overlap

ChIP fibroblast of lung ENCFF356FDN 317 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 251 bp overlap

DNMT3B 1 dataset

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 308 bp overlap

EGR1 1 dataset

ChIP HepG2 ENCFF674RQO 211 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 236 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 313 bp overlap

FOXA2 5 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 219 bp overlap

ChIP Caco-2 GSE66218.FOXA2.Caco-2 157 bp overlap

ChIP DE DE-FOXA2-1 543 bp overlap

ChIP DE DE-FOXA2-2 557 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 299 bp overlap

FOXN3 1 dataset

Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap

FOXP2 1 dataset

Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap

Foxl2 1 dataset

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA4 6 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 197 bp overlap

ChIP DE DE-GATA4-1 521 bp overlap

ChIP DE DE-GATA4-2 610 bp overlap

ChIP foregut GSE117136.GATA4.foregut 457 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 527 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 422 bp overlap

GATA6 10 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 265 bp overlap

ChIP DE DE-GATA6-1 615 bp overlap

ChIP DE DE-GATA6-2 545 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 552 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 243 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 146 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 325 bp overlap

ChIP foregut GSE117136.GATA6.foregut 453 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 466 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 401 bp overlap

HMGXB4 1 dataset

ChIP K562 ENCFF620JLK 241 bp overlap

ID3 1 dataset

ChIP K-562 ENCSR005NMT.ID3.K-562 309 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 196 bp overlap

JUNB 1 dataset

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 279 bp overlap

KLF4 1 dataset

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 144 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 145 bp overlap

NKX2-4 1 dataset

Motif DE_72h DE_72h-NKX2-4_MA2003.2 8 bp overlap

PML 1 dataset

ChIP K-562 ENCSR000BQY.PML.K-562 160 bp overlap

POLR2A 7 datasets

ChIP GM12878 ENCFF412KAE 399 bp overlap

ChIP GM12891 ENCFF127ICP 295 bp overlap

ChIP HepG2 ENCFF350RIU 331 bp overlap

ChIP HepG2 ENCFF718XAJ 338 bp overlap

ChIP K562 ENCFF214YGX 507 bp overlap

ChIP K562 ENCFF262YXJ 321 bp overlap

ChIP spleen ENCFF446ZGT 190 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBFOX2 3 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 283 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 283 bp overlap

ChIP K562 ENCFF967GRF 553 bp overlap

RBM22 4 datasets

ChIP HepG2 ENCFF292RVQ 182 bp overlap

ChIP HepG2 ENCFF561IAJ 117 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 111 bp overlap

ChIP K-562 GSE120104.RBM22.K-562 109 bp overlap

SIRT6 1 dataset

ChIP K-562 ENCSR000AUB.SIRT6.K-562 53 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 400 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 246 bp overlap

SMAD5 3 datasets

ChIP K-562 ENCSR000FCD.SMAD5.K-562 287 bp overlap

ChIP K562 ENCFF941FJJ 280 bp overlap

ChIP K562 ENCFF941FJJ 481 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 477 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 661 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 217 bp overlap

SUPT5H 2 datasets

ChIP K562 ENCFF902PAW 228 bp overlap

ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 104 bp overlap

THRA 1 dataset

Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap

YY1 1 dataset

ChIP Huh-7 GSE97411.YY1.Huh-7 230 bp overlap

ZBTB7A 1 dataset

ChIP HepG2 ENCFF492YYQ 364 bp overlap

ZNF143 1 dataset

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 162 bp overlap

ZNF184 1 dataset

Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap

ZNF257 1 dataset

Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 198 bp overlap

ZNF343 1 dataset

Motif DE_72h DE_72h-ZNF343_MA1711.2 16 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 220 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 187 bp overlap

ZNF883 1 dataset

ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 219 bp overlap

ZSCAN21 1 dataset

Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap

Zic1::Zic2 1 dataset

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap

Gene	Dist. to TSS	Distance	Link type
SEC13	4.3 kb	Proximal	Proximity
TATDN2	68.1 kb	Distal	Multiome
VHL	174.7 kb	Distal	Multiome
BRK1	200.9 kb	Distal	Multiome
FANCD2	290.1 kb	Distal	Multiome
ENSG00000291078	290.2 kb	Distal	Multiome

Genome Browser