chr1:32,643,807–32,644,727

chr1 : 32,643,807 – 32,644,727

920 bp 70 TFs 9 linked genes

This 920 bp open chromatin element is linked to 9 target genes and is bound by 70 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ZBTB8OS		5.8 kb	Proximal	Proximity
RBBP4		6.5 kb	Proximal	Proximity
SYNC		58.6 kb	Distal	Multiome
ZBTB8A		104.8 kb	Distal	Multiome
YARS1		173.2 kb	Distal	Multiome
S100PBP		173.4 kb	Distal	Multiome
ZBTB8B		179.1 kb	Distal	Multiome
BSDC1		249.8 kb	Distal	Multiome
TMEM54		257.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

70 transcription factors

BARHL1 2 datasets

Motif DE_48h DE_48h-BARHL1_MA0877.4 6 bp overlap

Motif DE_72h DE_72h-BARHL1_MA0877.4 6 bp overlap

BARHL2 2 datasets

Motif DE_48h DE_48h-BARHL2_MA0635.2 6 bp overlap

Motif DE_72h DE_72h-BARHL2_MA0635.2 6 bp overlap

BARX1 1 dataset

Motif DE_72h DE_72h-BARX1_MA0875.2 6 bp overlap

BCL6B 2 datasets

Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap

Motif DE_72h DE_72h-BCL6B_MA0731.1 17 bp overlap

Motif DE_72h DE_72h-BSX_MA0876.2 6 bp overlap

ChIP adrenal-gland ENCSR899JSO.CTCF.adrenal-gland 132 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF274GAT 163 bp overlap

ChIP BLaER1 ENCFF335XTP 366 bp overlap

ChIP BLaER1 ENCFF364PUR 185 bp overlap

ChIP BLaER1 ENCFF680YXW 251 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 215 bp overlap

Motif DE_72h DE_72h-DLX1_MA0879.3 6 bp overlap

Motif DE_72h DE_72h-DLX6_MA0882.2 6 bp overlap

Motif DE_72h DE_72h-Dlx2_MA0885.3 8 bp overlap

Motif DE_72h DE_72h-Dlx3_MA0880.2 6 bp overlap

Motif DE_72h DE_72h-Dlx4_MA0881.2 6 bp overlap

Motif DE_72h DE_72h-Dlx5_MA1476.3 8 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 180 bp overlap

ETV2::HOXB13 1 dataset

Motif DE_72h DE_72h-ETV2HOXB13_MA1943.2 13 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_72h DE_72h-ETV5HOXA2_MA1948.2 12 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 884 bp overlap

ChIP DE DE-FOXA2-2 884 bp overlap

GATA1::TAL1 1 dataset

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 801 bp overlap

ChIP DE DE-GATA4-2 828 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 354 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 849 bp overlap

ChIP DE DE-GATA6-2 815 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 435 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 315 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 737 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 366 bp overlap

ChIP foregut GSE117136.GATA6.foregut 261 bp overlap

Motif DE_72h DE_72h-GBX2_MA0890.2 6 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HESX1 1 dataset

Motif DE_72h DE_72h-HESX1_MA0894.2 6 bp overlap

HNF4A 1 dataset

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 162 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 179 bp overlap

HOXA6 1 dataset

Motif DE_72h DE_72h-HOXA6_MA1497.2 7 bp overlap

HOXA7 1 dataset

Motif DE_72h DE_72h-HOXA7_MA1498.3 6 bp overlap

HOXB6 1 dataset

Motif DE_72h DE_72h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_72h DE_72h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_72h DE_72h-HOXB8_MA1502.2 7 bp overlap

HOXD8 1 dataset

Motif DE_72h DE_72h-HOXD8_MA0910.3 7 bp overlap

HOXD9 1 dataset

Motif DE_72h DE_72h-HOXD9_MA0913.3 9 bp overlap

Motif DE_72h DE_72h-Hmx1_MA0896.2 9 bp overlap

Motif DE_72h DE_72h-Hmx2_MA0897.2 15 bp overlap

Motif DE_72h DE_72h-Hmx3_MA0898.2 9 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 155 bp overlap

Motif DE_72h DE_72h-LBX2_MA0699.2 6 bp overlap

Motif DE_72h DE_72h-LHX2_MA0700.3 6 bp overlap

Motif DE_72h DE_72h-MSX1_MA0666.3 6 bp overlap

Motif DE_72h DE_72h-MSX2_MA0708.3 6 bp overlap

Mecom 1 dataset

Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap

Motif DE_72h DE_72h-Msx3_MA0709.2 6 bp overlap

Nobox 1 dataset

Motif DE_72h DE_72h-Nobox_MA0125.2 6 bp overlap

PHF21A 1 dataset

ChIP Hep-G2 ENCSR315VYZ.PHF21A.Hep-G2 185 bp overlap

PHOX2A 1 dataset

Motif DE_72h DE_72h-PHOX2A_MA0713.1 11 bp overlap

Motif DE_72h DE_72h-RAX_MA0718.2 6 bp overlap

RBPJ 2 datasets

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 485 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 550 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 590 bp overlap

SMAD4 1 dataset

ChIP K562 ENCFF628RBP 541 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 225 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 288 bp overlap

ChIP Hep-G2 ENCSR766TSU.SOX6.Hep-G2 206 bp overlap

Stat5a 1 dataset

Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap

Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap

Stat6 2 datasets

Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap

Motif DE_72h DE_72h-Stat6_MA0520.2 10 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZBTB12 1 dataset

Motif DE_72h DE_72h-ZBTB12_MA1649.2 7 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZNF136 1 dataset

Motif DE_72h DE_72h-ZNF136_MA1588.1 15 bp overlap

ZNF143 1 dataset

Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap

ZNF22 1 dataset

ChIP HEK293 GSE76494.ZNF22.HEK293 157 bp overlap

ZNF362 2 datasets

ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 208 bp overlap

ChIP HepG2 ENCFF256AZN 368 bp overlap

ZNF384 2 datasets

ChIP Hep-G2 ENCSR101FJU.ZNF384.Hep-G2 324 bp overlap

ChIP HepG2 ENCFF129PLC 178 bp overlap

ZNF592 1 dataset

ChIP K562 ENCFF547OSS 605 bp overlap