chr17 : 72,816,220 – 72,816,808

588 bp 55 TFs 1 linked gene

This 588 bp open chromatin element is linked to SLC39A11 and is bound by 55 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
SLC39A11		276.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap

ARNTL 2 datasets

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 218 bp overlap

ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 241 bp overlap

CDX1 1 dataset

Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF460KDD 269 bp overlap

ChIP BLaER1 ENCFF680YXW 129 bp overlap

Crx 1 dataset

Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 316 bp overlap

FEZF2 1 dataset

Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 463 bp overlap

ChIP DE DE-FOXA2-2 470 bp overlap

FOXD2 1 dataset

Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 474 bp overlap

ChIP DE DE-GATA4-2 493 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 417 bp overlap

ChIP DE DE-GATA6-2 569 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 430 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 271 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 462 bp overlap

GSC 1 dataset

Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap

HES6 1 dataset

Motif DE_48h DE_48h-HES6_MA1493.1 10 bp overlap

MEIS1 1 dataset

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

MEIS2 1 dataset

Motif DE_48h DE_48h-MEIS2_MA0774.1 8 bp overlap

MEIS3 1 dataset

Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap

MZF1 1 dataset

Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap

NEUROD1 2 datasets

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 225 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 252 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap

OTX1 1 dataset

Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap

PAX5 1 dataset

Motif DE_48h DE_48h-PAX5_MA0014.4 8 bp overlap

PBX3 1 dataset

Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap

PDX1 1 dataset

ChIP islet ERP001456.PDX1.islet 143 bp overlap

PITX1 1 dataset

Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap

PKNOX1 1 dataset

Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap

PRDM1 1 dataset

Motif DE_48h DE_48h-PRDM1_MA0508.4 7 bp overlap

Prdm15 1 dataset

Motif DE_48h DE_48h-Prdm15_MA1616.2 11 bp overlap

Ptf1A 1 dataset

Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap

RHOXF1 1 dataset

Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap

RORA 1 dataset

Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap

RREB1 1 dataset

Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 174 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 544 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 341 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 311 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 463 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 588 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 153 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 210 bp overlap

SOX10 1 dataset

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 318 bp overlap

Sox11 1 dataset

Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 299 bp overlap

Thap11 1 dataset

Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap

ZBTB18 1 dataset

Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap

ZEB1 1 dataset

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZIM3 2 datasets

ChIP HEK293 GSE76494.ZIM3.HEK293 177 bp overlap

ChIP HEK293T GSE78099.ZIM3.HEK293T 237 bp overlap

ZKSCAN3 1 dataset

Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF184 1 dataset

Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap

ZNF558 1 dataset

Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap

ZNF768 2 datasets

Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap