Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

33 transcription factors

AR 2 datasets

ChIP LNCaP_G87R_shFOXA1_Ethanol GSE128883.AR.LNCaP_G87R_shFOXA1_Ethanol 90 bp overlap

ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 86 bp overlap

ASCL1 2 datasets

ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 189 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 199 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 201 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 251 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 324 bp overlap

ESR1 15 datasets

ChIP MCF-7 GSE117492.ESR1.MCF-7 218 bp overlap

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 141 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 218 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 198 bp overlap

ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 55 bp overlap

ChIP MCF-7_shFbxo_E2_4OHT GSE119702.ESR1.MCF-7_shFbxo_E2_4OHT 271 bp overlap

ChIP MCF-7_shFbxo_OHT GSE119702.ESR1.MCF-7_shFbxo_OHT 271 bp overlap

ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 141 bp overlap

ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 193 bp overlap

ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 131 bp overlap

ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 85 bp overlap

ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 257 bp overlap

ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 300 bp overlap

ChIP T-47D_siFOXA1-IL6 GSE126004.ESR1.T-47D_siFOXA1-IL6 303 bp overlap

ChIP primary-breast-cancer_B2_DSG GSE114737.ESR1.primary-breast-cancer_B2_DSG 154 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 226 bp overlap

ChIP DE DE-FOXA2-1 287 bp overlap

ChIP DE DE-FOXA2-2 423 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 187 bp overlap

GATA2 3 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 186 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 239 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 186 bp overlap

GATA3 6 datasets

ChIP Kelly GSE65664.GATA3.Kelly 230 bp overlap

ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 231 bp overlap

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 240 bp overlap

ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 243 bp overlap

ChIP MCF-7_ICI GSE81510.GATA3.MCF-7_ICI 152 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 72 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 161 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 252 bp overlap

ChIP DE DE-GATA4-1 631 bp overlap

ChIP DE DE-GATA4-2 719 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 278 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 610 bp overlap

ChIP DE DE-GATA6-2 617 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 552 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 646 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 719 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 719 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 719 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 719 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 605 bp overlap

HAND2 1 dataset

ChIP Kelly GSE94822.HAND2.Kelly 209 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 316 bp overlap

NANOG 2 datasets

ChIP LNCaP_pNanog1_Dox GSE74799.NANOG.LNCaP_pNanog1_Dox 117 bp overlap

ChIP LNCaP_pNanog8_Dox GSE74799.NANOG.LNCaP_pNanog8_Dox 123 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 220 bp overlap

NR3C1 1 dataset

ChIP MCF-7_E2_Dex GSE81510.NR3C1.MCF-7_E2_Dex 234 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 556 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 424 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 512 bp overlap

RELA 1 dataset

ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 64 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 472 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 569 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 332 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 252 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 719 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 493 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 354 bp overlap

STAT3 15 datasets

ChIP HCC1187 GSE152203.STAT3.HCC1187 310 bp overlap

ChIP HCC70 GSE152203.STAT3.HCC70 272 bp overlap

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 64 bp overlap

ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 221 bp overlap

ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 292 bp overlap

ChIP T-47D_JC4737 GSE126004.STAT3.T-47D_JC4737 90 bp overlap

ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 372 bp overlap

ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 334 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 234 bp overlap

ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 194 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 457 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 423 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 484 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 424 bp overlap

ChIP breast-cancer_3487 GSE126004.STAT3.breast-cancer_3487 167 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 200 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 284 bp overlap

TEAD4 1 dataset

ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 219 bp overlap

TFAP2A 1 dataset

ChIP MCF-7_E2 GSE60270.TFAP2A.MCF-7_E2 95 bp overlap

ZBTB6 1 dataset

ChIP HEK293 GSE76494.ZBTB6.HEK293 152 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 149 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 172 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 99 bp overlap

Gene	Dist. to TSS	Distance	Link type
INSYN1	6.8 kb	Proximal	Proximity
CD276	49.1 kb	Distal	Multiome
NPTN	100.1 kb	Distal	Multiome
LOXL1	192.9 kb	Distal	Multiome
PML	261.2 kb	Distal	Multiome

Genome Browser