Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

31 transcription factors

AHR 1 dataset

ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 311 bp overlap

BRD4 2 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 147 bp overlap

ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 335 bp overlap

CBX1 1 dataset

ChIP Hep-G2 ENCSR819WZE.CBX1.Hep-G2 188 bp overlap

CBX2 1 dataset

ChIP K-562 ENCSR000ATU.CBX2.K-562 297 bp overlap

CTBP2 1 dataset

ChIP MCF-7 GSE107013.CTBP2.MCF-7 111 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 71 bp overlap

ELF1 2 datasets

ChIP MCF-7 ENCFF305BNP 391 bp overlap

ChIP MCF-7 ENCSR000BSS.ELF1.MCF-7 205 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 138 bp overlap

ChIP hESC GSE26097.EOMES.hESC 188 bp overlap

ESR1 9 datasets

ChIP MCF-7 GSE68355.ESR1.MCF-7 411 bp overlap

ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 275 bp overlap

ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 310 bp overlap

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 387 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 212 bp overlap

ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 304 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 387 bp overlap

ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 205 bp overlap

ChIP T-47D_DMSO GSE148277.ESR1.T-47D_DMSO 224 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 666 bp overlap

ChIP DE DE-FOXA2-2 659 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 185 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 325 bp overlap

GATA2 2 datasets

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 144 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 282 bp overlap

GATA3 14 datasets

ChIP MCF-7 ENCFF178GBS 461 bp overlap

ChIP MCF-7 ENCFF178GBS 432 bp overlap

ChIP MCF-7 ENCFF352QVM 159 bp overlap

ChIP MCF-7 ENCFF437NQS 371 bp overlap

ChIP MCF-7 GSE51274.GATA3.MCF-7 287 bp overlap

ChIP MCF-7 GSE133072.GATA3.MCF-7 231 bp overlap

ChIP MCF-7 GSE122847.GATA3.MCF-7 268 bp overlap

ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 436 bp overlap

ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 142 bp overlap

ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 139 bp overlap

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 140 bp overlap

ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 266 bp overlap

ChIP T-47D GSE51274.GATA3.T-47D 315 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 152 bp overlap

GATA3_Cter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Cter.T-47D_CR3flp 205 bp overlap

GATA3_Nter 2 datasets

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 475 bp overlap

ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 238 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 773 bp overlap

ChIP DE DE-GATA4-2 840 bp overlap

ChIP foregut GSE117136.GATA4.foregut 769 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 560 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 522 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 751 bp overlap

ChIP DE DE-GATA6-2 831 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 586 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 307 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 840 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 641 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 391 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 693 bp overlap

ChIP foregut GSE117136.GATA6.foregut 776 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 747 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 574 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 363 bp overlap

HDAC1 1 dataset

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 459 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 461 bp overlap

LMO2 1 dataset

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 158 bp overlap

PGR 2 datasets

ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 360 bp overlap

ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 421 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 810 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 319 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 326 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 740 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 840 bp overlap

SMARCA4 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 121 bp overlap

SMARCB1 2 datasets

ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 298 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.SMARCB1.MCF-7_Fulvestrant 284 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 321 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 178 bp overlap

TFAP2C 2 datasets

ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 168 bp overlap

ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 159 bp overlap

TRPS1 1 dataset

ChIP MCF-7 GSE133072.TRPS1.MCF-7 165 bp overlap

ZNF579 2 datasets

ChIP MCF-7 ENCFF550XRS 315 bp overlap

ChIP MCF-7 ENCSR018MQH.ZNF579.MCF-7 200 bp overlap

Gene	Dist. to TSS	Distance	Link type
ENSG00000270000	989 bp	At TSS	Proximity
ENSG00000259005	3.5 kb	Proximal	Proximity
NPC2	22.5 kb	Distal	Multiome
ISCA2	22.9 kb	Distal	Multiome
VRTN	122.4 kb	Distal	Multiome+HiCAR
ABCD4	167.9 kb	Distal	Multiome+HiCAR
AREL1	242.2 kb	Distal	Multiome
FCF1	242.3 kb	Distal	Multiome
YLPM1	292.4 kb	Distal	Multiome

Genome Browser