chr14 : 56,657,366 – 56,658,170
804 bp 55 TFs 4 linked genes
This 804 bp open chromatin element is linked to 4 target genes and is bound by 55 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000258428 8.7 kb Proximal Proximity
TMEM260 78.0 kb Distal Multiome
OTX2 147.9 kb Distal Multiome
OTX2-AS1 155.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:56,652,366 – 56,663,170
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
55 transcription factors
Source
Cell type
CEBPB 1 dataset
ChIP OCI-AML3_JQ1_500nM_24h GSE104745.CEBPB.OCI-AML3_JQ1_500nM_24h 160 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF093OYK 271 bp overlap
ChIP BLaER1 ENCFF335XTP 257 bp overlap
E2F6 2 datasets
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 492 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_24h DE_24h-EWSR1-FLI1_MA0149.1 18 bp overlap
FIGLA 2 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 761 bp overlap
ChIP DE DE-FOXA2-2 699 bp overlap
FOXN3 2 datasets
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 716 bp overlap
ChIP DE DE-GATA4-2 641 bp overlap
ChIP foregut GSE117136.GATA4.foregut 277 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 241 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 651 bp overlap
ChIP DE DE-GATA6-2 737 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 464 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 381 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 352 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 407 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 518 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 531 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 531 bp overlap
ChIP foregut GSE117136.GATA6.foregut 386 bp overlap
GRHL1 2 datasets
Motif DE_48h DE_48h-GRHL1_MA0647.2 10 bp overlap
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
GRHL2 2 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Gli1 1 dataset
Motif DE_24h DE_24h-Gli1_MA1990.2 10 bp overlap
HOXA3 1 dataset
Motif DE_24h DE_24h-HOXA3_MA2119.1 7 bp overlap
HOXA4 1 dataset
Motif DE_24h DE_24h-HOXA4_MA1496.2 7 bp overlap
HOXA5 1 dataset
Motif DE_24h DE_24h-HOXA5_MA0158.2 8 bp overlap
HOXB13 1 dataset
Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap
HOXB4 1 dataset
Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap
HOXD3 1 dataset
Motif DE_24h DE_24h-HOXD3_MA0912.2 8 bp overlap
HOXD4 1 dataset
Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap
IRF7 1 dataset
Motif DE_24h DE_24h-IRF7_MA0772.2 13 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 345 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 518 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 290 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 565 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 174 bp overlap
MAFF 2 datasets
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 417 bp overlap
MYNN 2 datasets
ChIP HEK293 ENCSR707BNG.MYNN.HEK293 222 bp overlap
ChIP HEK293 GSE76494.MYNN.HEK293 214 bp overlap
MYOD1 2 datasets
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 261 bp overlap
NFIA 1 dataset
Motif DE_24h DE_24h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif DE_24h DE_24h-NFIX_MA0671.2 6 bp overlap
POU5F1 1 dataset
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 181 bp overlap
Ptf1A 2 datasets
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
RBPJ 2 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
SCRT1 3 datasets
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 400 bp overlap
SCRT2 3 datasets
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
ChIP HEK293 ENCFF711QQB 324 bp overlap
SMAD2 4 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 341 bp overlap
ChIP hESC GSE29422.SMAD2.hESC 157 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 446 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 290 bp overlap
SMAD2-3 5 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 668 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 692 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 804 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 175 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 215 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 673 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 675 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 741 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 662 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 685 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 268 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 240 bp overlap
SMARCA4 2 datasets
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 374 bp overlap
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 270 bp overlap
SNAI2 2 datasets
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap
SNAI3 2 datasets
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 285 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 552 bp overlap
STAT3 1 dataset
ChIP HCC1187 GSE152203.STAT3.HCC1187 314 bp overlap
TBX18 2 datasets
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
Tbx6 2 datasets
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZEB1 2 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZIC1 2 datasets
Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
ZIC4 2 datasets
Motif DE_48h DE_48h-ZIC4_MA0751.2 14 bp overlap
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
ZNF205 1 dataset
ChIP HEK293T GSE78099.ZNF205.HEK293T 64 bp overlap
ZNF75A 2 datasets
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
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