Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

38 transcription factors

CTCF 2 datasets

Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap

Motif DE_72h DE_72h-CTCF_MA0139.2 15 bp overlap

DMRTA1 2 datasets

Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap

Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap

DMRTA2 2 datasets

Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap

Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap

Ddit3::Cebpa 1 dataset

Motif DE_60h DE_60h-Ddit3Cebpa_MA0019.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 209 bp overlap

ERF::FOXO1 2 datasets

Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap

Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap

ERF::NHLH1 2 datasets

Motif DE_60h DE_60h-ERFNHLH1_MA1938.2 16 bp overlap

Motif DE_72h DE_72h-ERFNHLH1_MA1938.2 16 bp overlap

ESR1 1 dataset

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap

ETV5::FOXO1 2 datasets

Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap

Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 368 bp overlap

ChIP DE DE-FOXA2-2 460 bp overlap

FOXO1::FLI1 2 datasets

Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap

Motif DE_72h DE_72h-FOXO1FLI1_MA1956.2 13 bp overlap

FOXP2 2 datasets

Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap

Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap

Foxl2 2 datasets

Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA1::TAL1 2 datasets

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 3 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 161 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 250 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 260 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 615 bp overlap

ChIP DE DE-GATA4-2 808 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 518 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 330 bp overlap

GATA5 2 datasets

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 608 bp overlap

ChIP DE DE-GATA6-2 826 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 351 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 522 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 356 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 491 bp overlap

ChIP foregut GSE117136.GATA6.foregut 481 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 323 bp overlap

GLIS2 2 datasets

Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap

Motif DE_72h DE_72h-GLIS2_MA0736.1 14 bp overlap

GRHL1 2 datasets

Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap

Motif DE_72h DE_72h-GRHL1_MA0647.2 10 bp overlap

GRHL2 2 datasets

Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap

Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap

Gata3 2 datasets

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

MTF1 2 datasets

Motif DE_60h DE_60h-MTF1_MA0863.1 14 bp overlap

Motif DE_72h DE_72h-MTF1_MA0863.1 14 bp overlap

MYC 1 dataset

ChIP CD34 GSE85488.MYC.CD34 113 bp overlap

MZF1 1 dataset

Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap

Mecom 2 datasets

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap

NFKB1 4 datasets

ChIP CD4 GSE116695.NFKB1.CD4 305 bp overlap

ChIP CD4-pos GSE126505.NFKB1.CD4-pos 397 bp overlap

ChIP CD4-pos_ID206 GSE126505.NFKB1.CD4-pos_ID206 270 bp overlap

ChIP L1236 GSE63736.NFKB1.L1236 161 bp overlap

POU2F1 2 datasets

Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap

Motif DE_72h DE_72h-POU2F1_MA0785.2 9 bp overlap

POU5F1 2 datasets

Motif DE_60h DE_60h-POU5F1_MA1115.2 7 bp overlap

Motif DE_72h DE_72h-POU5F1_MA1115.2 7 bp overlap

REST 2 datasets

Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap

Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 593 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 754 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 178 bp overlap

TRPS1 2 datasets

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZIC1 2 datasets

Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

ZIC4 2 datasets

Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

ZIC5 3 datasets

Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap

Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap

ChIP HCT-116_WT-CT289 GSE127960.ZIC5.HCT-116_WT-CT289 189 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 123 bp overlap

Gene	Dist. to TSS	Distance	Link type
KLRG1	81.0 kb	Distal	Multiome+HiCAR
M6PR	81.3 kb	Distal	Multiome+HiCAR
PHC1	117.1 kb	Distal	Multiome+HiCAR
A2ML1	207.5 kb	Distal	Multiome
LINC02972	242.8 kb	Distal	Multiome

Genome Browser