chr4 : 86,309,328 – 86,310,316
988 bp 57 TFs 2 linked genes
This 988 bp open chromatin element is linked to MAPK10 and PTPN13 and is bound by 57 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MAPK10 284.1 kb Distal Multiome
PTPN13 284.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:86,304,328 – 86,315,316
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
57 transcription factors
Source
Cell type
BARHL1 2 datasets
Motif DE_48h DE_48h-BARHL1_MA0877.4 6 bp overlap
Motif DE_72h DE_72h-BARHL1_MA0877.4 6 bp overlap
BARHL2 2 datasets
Motif DE_48h DE_48h-BARHL2_MA0635.2 6 bp overlap
Motif DE_72h DE_72h-BARHL2_MA0635.2 6 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF274GAT 251 bp overlap
DMRTA1 4 datasets
Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap
DMRTC2 2 datasets
Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 316 bp overlap
ETV5::DRGX 3 datasets
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::HOXA2 3 datasets
Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_60h DE_60h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_72h DE_72h-ETV5HOXA2_MA1948.2 12 bp overlap
FLI1::DRGX 3 datasets
Motif DE_48h DE_48h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_60h DE_60h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_72h DE_72h-FLI1DRGX_MA1949.2 14 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 932 bp overlap
ChIP DE DE-FOXA2-2 855 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 773 bp overlap
ChIP DE DE-GATA4-2 952 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
GATA6 4 datasets
ChIP DE DE-GATA6-1 650 bp overlap
ChIP DE DE-GATA6-2 959 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 809 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 549 bp overlap
GRHL1 2 datasets
Motif DE_48h DE_48h-GRHL1_MA0647.2 10 bp overlap
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
GRHL2 2 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
HNF4A 3 datasets
Motif DE_48h DE_48h-HNF4A_MA1494.2 14 bp overlap
Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap
Motif DE_72h DE_72h-HNF4A_MA1494.2 14 bp overlap
Hnf1A 3 datasets
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
IRF9 2 datasets
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
LIN54 3 datasets
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap
Lef1 3 datasets
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap
MYBL2 3 datasets
Motif DE_48h DE_48h-MYBL2_MA0777.1 15 bp overlap
Motif DE_60h DE_60h-MYBL2_MA0777.1 15 bp overlap
Motif DE_72h DE_72h-MYBL2_MA0777.1 15 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 334 bp overlap
NFATC3 3 datasets
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
NR1H2::RXRA 3 datasets
Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap
NR1I2 3 datasets
Motif DE_48h DE_48h-NR1I2_MA1533.2 15 bp overlap
Motif DE_60h DE_60h-NR1I2_MA1533.2 15 bp overlap
Motif DE_72h DE_72h-NR1I2_MA1533.2 15 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
NR3C1 3 datasets
Motif DE_48h DE_48h-NR3C1_MA0113.4 15 bp overlap
Motif DE_60h DE_60h-NR3C1_MA0113.4 15 bp overlap
Motif DE_72h DE_72h-NR3C1_MA0113.4 15 bp overlap
NR3C2 3 datasets
Motif DE_48h DE_48h-NR3C2_MA0727.2 15 bp overlap
Motif DE_60h DE_60h-NR3C2_MA0727.2 15 bp overlap
Motif DE_72h DE_72h-NR3C2_MA0727.2 15 bp overlap
Nanog 3 datasets
Motif DE_48h DE_48h-Nanog_MA2339.1 7 bp overlap
Motif DE_60h DE_60h-Nanog_MA2339.1 7 bp overlap
Motif DE_72h DE_72h-Nanog_MA2339.1 7 bp overlap
Nfat5 2 datasets
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 3 datasets
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Nr2e3 2 datasets
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_72h DE_72h-Nr2e3_MA0164.2 6 bp overlap
Nr2f6 3 datasets
Motif DE_48h DE_48h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_72h DE_72h-Nr2f6_MA0677.2 13 bp overlap
ONECUT3 2 datasets
Motif DE_48h DE_48h-ONECUT3_MA0757.2 12 bp overlap
Motif DE_60h DE_60h-ONECUT3_MA0757.2 12 bp overlap
PAX6 2 datasets
Motif DE_48h DE_48h-PAX6_MA0069.1 14 bp overlap
Motif DE_60h DE_60h-PAX6_MA0069.1 14 bp overlap
PGR 3 datasets
Motif DE_48h DE_48h-PGR_MA2327.1 9 bp overlap
Motif DE_60h DE_60h-PGR_MA2327.1 9 bp overlap
Motif DE_72h DE_72h-PGR_MA2327.1 9 bp overlap
PPARD 3 datasets
Motif DE_48h DE_48h-PPARD_MA1550.2 14 bp overlap
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap
Prdm4 2 datasets
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
Prdm5 3 datasets
Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap
Motif DE_60h DE_60h-Prdm5_MA1999.2 11 bp overlap
Motif DE_72h DE_72h-Prdm5_MA1999.2 11 bp overlap
RXRA::VDR 3 datasets
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap
RXRB 3 datasets
Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 3 datasets
Motif DE_48h DE_48h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Rxra 3 datasets
Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 175 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 544 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 374 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 482 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 198 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 154 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 480 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 813 bp overlap
SOX8 3 datasets
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 203 bp overlap
TCF7L1 3 datasets
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 3 datasets
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
THRB 3 datasets
Motif DE_48h DE_48h-THRB_MA1574.2 13 bp overlap
Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
ZNF324 3 datasets
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap
Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap
ZSCAN21 5 datasets
Motif DE_48h DE_48h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_48h DE_48h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap
Znf423 2 datasets
Motif DE_48h DE_48h-Znf423_MA0116.1 15 bp overlap
Motif DE_72h DE_72h-Znf423_MA0116.1 15 bp overlap
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