chr2 : 98,090,924 – 98,091,296

372 bp 50 TFs 1 linked gene

This 372 bp open chromatin element is linked to VWA3B and is bound by 50 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
VWA3B		3.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

BRD4 1 dataset

ChIP MV4-11-B_DMSO GSE101821.BRD4.MV4-11-B_DMSO 228 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 206 bp overlap

Crx 1 dataset

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

FEZF2 1 dataset

Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap

FOSL2 1 dataset

Motif DE_72h DE_72h-FOSL2_MA0478.2 10 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 295 bp overlap

GATA1 4 datasets

Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 363 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 154 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 162 bp overlap

GATA1::TAL1 1 dataset

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 356 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 372 bp overlap

ChIP DE DE-GATA4-2 372 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 372 bp overlap

ChIP DE DE-GATA6-2 372 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 326 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 350 bp overlap

GSC 1 dataset

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

HIF1A 1 dataset

Motif DE_72h DE_72h-HIF1A_MA1106.2 6 bp overlap

HNF1A 1 dataset

Motif DE_72h DE_72h-HNF1A_MA0046.3 13 bp overlap

HOXB4 1 dataset

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

IRF1 1 dataset

ChIP K-562_EPZ GSE129380.IRF1.K-562_EPZ 194 bp overlap

KDM1A 2 datasets

ChIP K-562 GSE117944.KDM1A.K-562 190 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 222 bp overlap

KMT2A 1 dataset

ChIP THP-1 GSE79899.KMT2A.THP-1 133 bp overlap

NKX6-3 1 dataset

Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap

Nr2e3 1 dataset

Motif DE_72h DE_72h-Nr2e3_MA0164.2 6 bp overlap

OTX1 1 dataset

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POU6F1 1 dataset

Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap

PPARG 1 dataset

Motif DE_72h DE_72h-PPARG_MA0066.2 19 bp overlap

Prdm15 1 dataset

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 195 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 372 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 278 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 244 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 258 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 182 bp overlap

TAL1 4 datasets

ChIP K-562 GSE107726.TAL1.K-562 231 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 174 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 155 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 205 bp overlap

TBP 1 dataset

ChIP K-562 ENCSR000EHA.TBP.K-562 109 bp overlap

TEAD1 2 datasets

Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

TEAD3 2 datasets

Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

ZBTB6 1 dataset

Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap

ZNF135 1 dataset

Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap

ZNF454 1 dataset

Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap

ZNF680 1 dataset

Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap

ZNF770 1 dataset

Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap